PLoS ONE
Articles in this Issue
GS-YOLO: A lightweight high-accuracy model for small target detection in drone aerial images
For the problems of weak feature representation, significant scale variation, and background interference in small target features of unmanned aerial vehicle (UAV) aerial images, existing detection me...
Can AI applied on MRI reliably predict shunt response in INPH? A comprehensive exploration of deep learning and radiomics approaches using preoperative MRI
Objective Idiopathic normal pressure hydrocephalus (INPH) is a treatable neurological condition, yet predicting which patients will benefit from a cerebrospinal fluid shunt remains...
Applying an extended Health Policy Analysis framework to digitally mediated health system reform: Evidence from Saudi Arabia’s Health Sector Transformation Program
Health policy analysis frameworks play a central role in understanding how reforms are designed, implemented, and experienced in practice. Walt and Gilson’s Health Policy Analysis Triangle has been wi...
Identity and mobility through personal ornaments in Upper Paleolithic cantabrian hunter-gatherer societies: Insights from Llonín cave (Asturias, Spain)
The use of personal ornaments is considered a milestone in human cognitive evolution and the development of complex behavior. The Cantabrian region in the north of the Iberian Peninsula served as a hu...
Rate of decline in residual kidney function and cognitive impairment in incident haemodialysis patients: A prospective, longitudinal analysis of the BISTRO trial cohort
Background Previous studies suggest loss of residual kidney function (RKF) on haemodialysis is associated with cognitive impairment (CI). This study investigated the association of...
Professionals’ perceptions of interprofessional collaboration within condition-based units
Introduction Hospitals can form condition-based units (CBUs) to support value-based healthcare (VBHC). Interprofessional collaboration is key to the success of CBUs, but insights i...
Study on the pollution law of complex working conditions in sand-filled fracture well washing operation
Aiming at the problem of wellbore leakage in the process of sand washing in horizontal wells, this study systematically analyzed the influence of temperature and pressure on the plugging behavior of f...
Evaluating physiological responses and forward head-neck posture in primary students in Thailand when carrying modified and traditional backpacks
Carrying backpacks daily imposes a physical burden on school-aged children, raising increasing public concern. This study compared the physiological responses and head–neck posture of primary school s...
Biochemical and molecular insights into anthracnose resistance in chilli
Hot pepper ( Capsicum annuum L.) is a globally important vegetable crop valued for its nutritional, economic, and culinary significance, yet its productivity is...
Edge-focused wire arc additive manufacturing: Method development with ANN-based stress–strain and mass-efficiency
This study evaluates Edge-Focused Wire Arc Additive Manufacturing (EF-WAAM) for CT38 steel using an ER70S-6 filler. EF-WAAM employs an edge-guided toolpath with a prescribed travel angle to localize h...
Clinicopathological features and ethnic disparities of melanoma in the United Arab Emirates: 2017–2025
Background Cutaneous melanoma incidence is rising globally, yet clinicopathological data from the high ultraviolet (UV) environment in the United Arab Emirates (UAE), with its dive...
Mental health and suicide literacy among school nurses in Japan: A cross-sectional study
Background School nurses (SN) are key providers of school health services and play a vital role in promoting adolescent mental health and preventing suicide. However, research into...
Navigating the digital era: The impact of digitalization and work-life harmony on well-being among solo self-employed individuals
In an era where technological advancements and work-life integration significantly shape the professional landscape, understanding their impact on individual job satisfaction and well-being is crucial...
Reliability-based mix design for concrete compressive strength using a physics-prior residual-learning surrogate with calibrated uncertainty
An integrated framework is presented for concrete compressive strength prediction and reliability-based mix design under data-scarce conditions, in which a physics-prior residual surrogate and uncerta...
Prevalence and determinants of metabolic syndrome among long-shift healthcare professionals in primary hospitals of Central Gondar Zone, Northwest Ethiopia
Background Metabolic syndrome (MetS) is a group of interrelated metabolic aberrations that significantly elevates the risk of poor cardiovascular outcomes and type 2 diabetes melli...
Clinical performance of the BioFire Blood Culture Identification 2 panel for microorganism species identification and resistance gene detection in blood culture-positive specimens
Introduction Bloodstream infections are life-threatening, and the rapid identification of pathogens and resistance genes is essential for the administration of appropriate antimicr...
Explainable IAOA-CNN-CBAM-SVR model for predicting air consumption of auxiliary nozzles with limited sample size
Air-jet looms are energy-intensive machines, with auxiliary nozzles accounting for nearly 80% of the total compressed air consumption. However, accurate prediction and visual analysis of nonlinear air...
Clinical characteristics and management strategies in adult foreign-body airway obstruction: A retrospective cohort study
Airway foreign-body aspiration in adults is uncommon but can be life-threatening.Flexible bronchoscopy is the standard first-line therapy,but critically ill patients may need extracorporeal life suppo...
Changes in tobacco sales before, during, and after the COVID-19 pandemic in Japan: An interrupted time series analysis
Objectives This study aimed to longitudinally examine nationwide changes in smoking behavior among the Japanese population in response to the COVID-19 pandemic....
Youth’s mental health journeys through the COVID-19 pandemic using arts-based methods in virtual environments
Already facing a crisis, youth mental health and well-being has been dramatically affected by the COVID-19 pandemic. Recognizing this decline in youth mental health is expected to last well into the f...
Multistate animal-contact-related nontyphoidal Salmonella enterica outbreaks in the United States, 2009–2022: Network and machine learning analyses of exposure sources, settings, and serovars
Background Nontyphoidal Salmonella enterica (NTS) is a major public‑health threat in the United States of America...
Large-scale statistical dissection of sequence-derived biochemical features distinguishing soluble and insoluble proteins
Protein solubility critically influences recombinant expression efficiency and downstream biotechnological applications. While deep learning models have improved predictive accuracy, the intrinsic mag...
Lived experiences of type 2 diabetes self-management in Jordan: A qualitative study of sociocultural, religious, and healthcare influences
Aim To explore the experiences of Jordanian adults living with T2DM and understand the influence of sociocultural, religious, emotional, and healthcare factors on their daily self-...
Deep learning models built from PSMA PET of the primary tumor can predict synchronous and metachronous prostate cancer metastases
Objective The objective was to develop prognostic models that included convolutional neural networks (CNN) derived from 18...
Decadal patterns of disaster damage and recovery-to-damage dynamics in South Korea (2015–2024) with a context-sensitive comparison to Japan
Understanding disaster recovery is essential for effective risk management, yet recovery processes are often implicitly assumed to scale proportionally with disaster damage. This study examines disast...