PLoS ONE
Articles in this Issue
Factors associated with female infertility in Ethiopia: A systematic review and meta-analysis
Background Infertility is a significant public health issue that affects couples worldwide. The impacts of infertility is notably higher in Ethiopia due to various factors, such as cultural stigmas su...
Outpatient care changes and associated mortality among Veterans with heart failure during the COVID-19 pandemic
Background The mortality risk associated with loss of in-person outpatient visits or transition to virtual care in patients with heart failure (HF) during the COVID-19 pandemic is unknown. Objective...
Analysis of government subsidy strategies in the supply chain of science and technology innovation platform
In the current era of technological advancements and intense global competition, innovation in Science and Technology (S&T) has become a crucial aspect of every country’s development strategy, and...
Multivariable prediction of early malignancy detection among first-degree relatives of patients with hereditary colorectal cancer based on the health belief model: A cross-sectional study from the largest hereditary colorectal cancer cohort in China
Background First-degree relatives (FDRs) of hereditary colorectal cancer are at an increased risk of cancer and receiving early detection and surveillance on malignancies is an efficacious strategy to...
Menstrual disturbance associated with COVID-19 vaccines: A comprehensive systematic review and meta-analysis
Background The relationship between COVID-19 vaccines and menstrual disturbance is unclear, in part because researchers have measured different outcomes (e.g., delays vs. changes to cycle length) with...
Flourishing at work: Psychometric properties of the Polish version of the Workplace PERMA-Profiler
The main purpose of this study was to investigate the validity of the Polish version of the Workplace PERMA-Profiler (WPP). Our work was guided by Martin Seligman’s perspective on positive psychology,...
A comparative study on immune responses to demineralized and decellularized bone substitute following intraperitoneal implantation in mouse model
The immunological sensitization of implanted bone grafts is crucial for long-term success. This study aimed to investigate the immune responses following implantation of lyophilized demineralized (DMB...
A robust optimization model for allocation-routing problems under uncertain conditions
Post-earthquake emergency logistics faces significant challenges such as limited resources, uncertain casualty numbers, and time constraints. Developing a scientific and efficient rescue plan is cruci...
What factors enhance students’ achievement? A machine learning and interpretable methods approach
Prior research on student achievement has typically examined isolated factors or bivariate correlations, failing to capture the complex interplay between learning behaviors, pedagogical environments,...
Applying a system dynamics approach for decision-making in software testing projects
Enhancing software quality remains a main objective for software developers and engineers, with a specific emphasis on improving software stability to increase user satisfaction. Developers must balan...
Pre-transplant residual diuresis and oxalic acid concentration influence kidney graft survival
Background and hypothesis Oxalic acid, a toxic metabolic end product, accumulates when kidney function deteriorates. Apart from its direct tubulotoxicity, it crystallizes at concentrations above 30–40...
Efficacy and safety of rifaximin in preventing hepatic encephalopathy: A systematic review and meta-analysis
Rifaximin (RFX) is recommended for the treatment of hepatic encephalopathy (HE). However, evidence on whether RFX application could yield additional benefits for preventing HE in patients with cirrhos...
Studying the decontamination process of an irradiated beryllium reflector in a chlorine environment
Beryllium, possessing unique nuclear physical properties, is currently widely used as a material for reflector and neutron moderator blocks of research nuclear reactors. It can also be applied in fusi...
Protocol: Weight-adjusted effective volume of 0.5% ropivacaine for combined costoclavicular brachial plexus block–cervical plexus blocks undergoing arthroscopic shoulder surgery: A dose-finding study protocol
Introduction Rotator cuff injuries are common clinically, and arthroscopic repair is widely applied. Postoperative analgesia can be assisted by the interscalene brachial plexus block; however, it come...
Scoping review of evidence synthesis: Concepts, types and methods
Objectives To systematically explore the concepts, types, and methodologies related to literature reviews and evidence synthesis. Methods We conducted a scoping review using PubMed, Embase, Bibliote...
Bacterial profile and antimicrobial susceptibility pattern of community and hospital-acquired urinary tract infections among UTI suspected geriatrics in Gondar town, Northwest Ethiopia
Background Bacterial urinary tract infection (UTI) is the second most frequent infection next to respiratory tract infection within the geriatric population both in the community and hospital settings...
Expected length of stay in residential aged care facilities in Australia: Assessing the impact of dementia using machine learning
Effectiveness of care coordination interventions delivered to stroke survivors in low and middle-income countries: Systematic review and meta-analysis protocol
Background Stroke survivors have complex and long-term care needs requiring navigation of multiple care services and providers. Care coordination interventions provide wholistic care that meets the ne...
Correction: Recency and rarity effects in disambiguating the focus of utterance: A developmental study
Autonomous adaptive optimization of NMR experimental conditions for precise inference of minor conformational states of proteins based on chemical exchange saturation transfer
In scientific experiments where measurement sensitivity is a major limiting factor, the optimization of experimental conditions, such as measurement parameters, is essential to maximize the informatio...
Inhibition of VE-PTP rejuvenates Schlemm’s canal in aged mice and acts via Tie2
Purpose Glaucoma is the leading cause of irreversible blindness worldwide and is associated with high intraocular pressure (IOP). Schlemm’s canal (SC), a hybrid vessel present in the anterior part of...
Neutrophil-to-lymphocyte ratio as a potential biomarker in predicting in-stent restenosis: A systematic review and meta-analysis
Background In-stent restenosis (ISR) remains a significant challenge despite advancements in percutaneous interventions, often leading to adverse clinical outcomes. The neutrophil-to-lymphocyte ratio...
Image rain removal network based on checkerboard transformer and CNN hybrid mechanism
In this paper, a novel hybrid network called ChessFormer is proposed for the single image de-rain task. The network seamlessly integrates the advantages of Transformer and fitted neural network (CNN)...
Diagnosis, clinical features, and mortality risk factors in a Chinese cohort with pulmonary mucormycosis
Background Pulmonary mucormycosis is a rare and often fatal fungal infection. Identifying high-risk factors for pulmonary mucormycosis holds the potential to improve patient outcomes. This study aimed...
Identifying opioid agonist treatment prescriber networks from health administrative data: A validation study
Background Given the growth of collaborative care strategies for people with opioid use disorder and the changing composition of the illicit drug supply, there is a need to identify and analyze clinic...