PLoS ONE
Articles in this Issue
Urinary MCP-1 and VCAM-1 as non-invasive biomarkers for the diagnosis and activity assessment of lupus nephritis
Introduction Accurate diagnosis of lupus nephritis (LN) and effective assessment of its disease activity are essential for optimal management. This study aimed to evaluate the potential of novel urina...
Safety and efficacy of antigen-specific therapeutic approaches for multiple sclerosis: Systematic review
Introduction The objective of this systematic review is to evaluate the efficacy and safety of antigen-specific tolerance-inducing therapeutic approaches (products based on peptides, DNA and T cells)...
Validation of dietary whey protein substrate challenge absorption test as an indicator of proteolysis
Introduction Current methods to measure the effectiveness of pancreatic protease activity are inadequate. We explored the measurement of peptide-derived amino acids following ingestion of dietary whey...
Early neurological deterioration in patients with minor stroke: A single-center study conducted in Vietnam
A minor ischemic stroke is associated with a higher likelihood of poor clinical outcomes at 90 days when there is early neurological deterioration (END). The objective of this case-control study condu...
Research on target detection based on improved YOLOv7 in complex traffic scenarios
Target detection is an essential direction in artificial intelligence development, and it is a crucial step in realizing environmental awareness for intelligent vehicles and advanced driver assistance...
The global burden of Klebsiella pneumoniae-associated lower respiratory infection in 204 countries and territories, 1990–2021: Findings from the global burden of disease study 2021
This study investigates the global epidemiological burden of lower respiratory infections (LRI) attributable to Klebsiella pneumoniae from 1990–2021, using data from the Global Burden of Disease Study...
A critical realist analysis of nursing educators’ willingness to learn and teach patient safety in Sri Lanka: Study protocol
Introduction Nursing educators’ willingness to learn and teach patient safety is identified as a challenge in the process of implementing patient safety education in nursing programmes. However, the l...
New perspectives on university quality assessment: A Mamdani Fuzzy Inference System approach
Higher education has traditionally played the role of an overarching factor in economic growth and development. The implementation of the European Higher Education Area (EHEA) has already achieved imp...
A simple statistical model and physical device to estimate a woman-specific probability of skilled birth assistance and associated benefit of maternity waiting home stay
This paper presents a simple mathematical model and an associated physical device to predict (i) the risk that a woman’s active labour will begin without a skilled birth attendant based on her parity...
Pharmaceutical enterprises integrity supervision strategy when considering rent-seeking behavior and government reward and punishment mechanism
The integrity of pharmaceutical enterprises is crucial to public health, social stability, and national security, consistently garnering attention from both the government and society. The efficiency...
Exploring natural allies: Survey and identification of larval parasitoids of the American grape berry moth, Paralobesia viteana (Lepidoptera: Tortricidae) in northwestern Pennsylvania
The American grape berry moth (GBM), Paralobesia viteana (Clemens) (Lepidoptera: Tortricidae) is an economically important pest of grapes. The larvae of this insect burrow inside the fruit upon hatchi...
Enhanced MRI-PET fusion using Laplacian pyramid and empirical mode decomposition for improved oncology imaging
In the field of oncology imaging, the fusion of magnetic resonance imaging (MRI) and positron emission tomography (PET) modalities is crucial for enhancing diagnostic capabilities. This article introd...
AI-driven educational transformation in ICT: Improving adaptability, sentiment, and academic performance with advanced machine learning
This study significantly contributes to the sphere of educational technology by deploying state-of-the-art machine learning and deep learning strategies for meaningful changes in education. The hybrid...
Yeast-based attract-and-kill strategies for Drosophila suzukii management without disrupting honey bee activity
Attract-and-kill strategies are effective, sustainable pest control methods. Formulations combining the insecticide spinosad, at a lower dose than conventional methods, with the Drosophila-associated...
Paving the way for rural revitalization: Empirical analysis of the ‘Sihao Rural Road Policy’ and transport mode choice in Inner Mongolia, China
This study investigates the impact of the Sihao Rural Road (SHRR) Program on travel behavior in Qingshuihe County, Inner Mongolia, China focusing on travel mode choice, travel frequency, and travel di...
Biofilms and antibiotic resistance profile of Enterococcus faecalis in selected dairy cattle farm environments in Bangladesh
Enterococci are opportunistic zoonotic pathogens. Dairy cattle and farm environments are considered important sources of Enterococcus spp. Here, we detected biofilm-forming Enterococcus faecalis circu...
Granulocyte-macrophage colony-stimulating factor reduces lung bacterial load following traumatic brain injury and hemorrhage polytrauma in a juvenile rat model
Traumatic brain injury (TBI) in children is associated with high rates of morbidity and mortality. Nosocomial respiratory infections are common following severe TBI, especially with polytraumatic TBI....
Bank performance and Non-interest income diversification: Evidence from Chinese commercial banks
This paper aims to investigate the impact of non-interest income diversification on the performance of commercial banks in China. We conduct an empirical analysis using the panel data of 159 Chinese c...
Real estate valuation with multi-source image fusion and enhanced machine learning pipeline
The automated valuation model (AVM) has been widely used by real estate stakeholders to provide accurate property value estimations automatically. Traditional valuation models are subjective and inacc...
Target-tracking control method for autonomous vehicles based on hyperbolic-tangent line-of-sight guidance and odometry error compensation
The target-tracking accuracy of autonomous vehicles is closely related to that of onboard sensors. Methods such as image processing and base station positioning are susceptible to various types of int...
Comparison and bias analysis of medically attended acute gastroenteritis incidence estimates derived from electronic health record surveillance versus cross-sectional surveys
Disease burden studies commonly use data from electronic health records (EHRs) or community surveys. Quantitative bias assessments of these study designs are needed. We compared two studies on acute g...
How can multiple benefit drivers improve corporate ESG performance?—The effects of green technology innovation and peer pressure
To achieve the ‘carbon peaking and carbon neutrality’ objectives, there has been a growing interest in corporate environmental, social, and governance (ESG) performance from governmental and superviso...
Efficacy and safety of the early implementation of a multimodal rehabilitation program in mechanically ventilated patients: A randomized clinical trial protocol
Background Intensive care unit-acquired weakness (ICUAW) and post-intensive care syndrome (PICS) are significant complications among critically ill patients, leading to prolonged hospital stays, incre...
The effects of handling on mouse behavior: cupped hands versus familiar or novel huts or tunnels
Mice are commonly tail-handled, despite evidence that this is aversive. Alternatives include cupping and tunnel handling; both methods are associated with improved welfare outcomes, including reduced...
SMART (artificial intelligence enabled) DROP (diabetic retinopathy outcomes and pathways): Study protocol for diabetic retinopathy management
Introduction Delayed diagnosis of diabetic retinopathy (DR) remains a significant challenge, often leading to preventable blindness and visual impairment. Given that physicians are frequently the firs...