PLoS ONE
Articles in this Issue
The probability of reducing hospitalization rates for bronchiolitis with epinephrine and dexamethasone: A Bayesian analysis
Background Bronchiolitis exerts a high burden on children, their families and the healthcare system. The Canadian Bronchiolitis Epinephrine Steroid Trial (CanBEST) assessed whether administering epine...
Evaluation for the operational risk factors of public transportation process based on entropy weighted- DEMATEL method
Identifying and assessing the key factors that influence the operations of public transportation from an operational risk perspective is a critical challenge. In this paper, in order to tackle this is...
An efficient leukemia prediction method using machine learning and deep learning with selected features
Leukemia is a serious problem affecting both children and adults, leading to death if left untreated. Leukemia is a kind of blood cancer described by the rapid proliferation of abnormal blood cells. A...
Parent-mediated interventions versus usual care in children with autism spectrum disorders: A protocol for a systematic review with meta-analysis and Trial Sequential Analysis
Introduction Autism spectrum disorder encompasses diverse patterns of social communication and repetitive, restricted behaviours. Various interventions have been developed to reduce the negative conse...
Chemotherapy-related adverse drug reaction and associated factors among adult cancer patient attending Jimma medical center oncology unit, Southwest Ethiopia
Background In 2017, reports of adverse drug reactions worldwide reached an estimated 35 million.Chemotherapeutic agents were one of the most often implicated pharmacological classes in inducing advers...
The neuronal chaperone proSAAS is highly expressed in the retina
The many layers of the neuroretina contain a complex, interconnected network of specialized neurons that both process visual stimuli and conduct processed information to higher brain areas. Neural net...
Distribution analysis of the finless porpoises (Neophocaena sp.) and oceanic dolphins (Delphinidae) in the Korean Sea using environmental DNA
Environmental DNA (eDNA) serves as a non-invasive tool for monitoring the presence of specific organisms in challenging or hard-to-access areas. We attempted non-invasive monitoring of Korean cetacean...
What is the lifetime cost of alcohol consumption? an estimation of economic burden in Thailand
This study aimed to estimate the lifetime cost of alcohol consumption per individual drinker in Thailand to support policy formulation. Using an incidence-based cost-of-illness (COI) approach, a hybri...
Evaluating the effectiveness of a population-level health intervention to increment HCV treatment coverage in tuscany region, Italy: An interrupted time series analysis
Worldwide, an estimated 57.8 million people are chronically infected with the Hepatitis C virus (HCV). The advent of direct-acting antivirals (DAAs) has made possible the definition of elimination tar...
Characteristics and incidence trends of adults hospitalized with community-acquired pneumonia in Portugal, pre-pandemic
Community-acquired pneumonia (CAP) is a major cause of hospitalization that leads to substantial morbidity, mortality, and costs. Evaluating CAP trends over time is important to understand patterns an...
Evaluation of the coupling coordination effect of Hefei Rail transit station area based on supply and demand matching
The coupling of supply and demand in the rail transit station area is an important driving force for ensuring the balanced development between the traffic functions and the place performance of the ra...
Application of stochastic fractal search algorithm in novel harmonic blocking filter design for optimizing harmonic mitigation and hosting capacity in electric distribution systems
Power networks are being transformed by the incorporation of renewable energy sources (RES), such as photovoltaic systems and wind turbines, which also promote sustainability and lower carbon emission...
Evaluation of the performance of three pulse oximeters at different probe positions in awake rabbits
In rabbits, pulse oximetry plays a crucial role in monitoring oxygen saturation (SpO2) and pulse rate (PR), but it can be challenging due to their small size, variable anatomy, limited measurement sit...
A fast hyperspectral change detection algorithm for agricultural crops based on spatial reconstruction
Crop change detection plays a pivotal role in ensuring agricultural sustainability and environmental monitoring. Leveraging the high spectral resolution of hyperspectral imagery and bi-temporal analys...
Investigating the accuracy of Apple Watch VO2 max measurements: A validation study
VO2 max is a measure of cardiorespiratory fitness and a key indicator of overall health. It is predictive of cardiovascular events and shows a strong inverse association with all-cause mortality. Incr...
The effect of different materials under the fencing piste on impact shock of the tibia during the fencing lunge on a concrete surface
Fencing has gained global popularity, with athletes often competing on hard surfaces, especially at United States national tournaments in convention centre with concrete floors. These surfaces may con...
Аmygdala DEGs are associated with the immune system function: A comparative transcriptomic study of high- and low-excitability rat strains
The aim of this study was to investigate differentially expressed genes (DEGs) in the amygdala of Rattus norvegicus with contrasting levels of nervous system excitability (high- and low-excitability)....
Blood urea nitrogen to albumin ratio as predictor of mortality among acute pancreatitis patients in ICU: A retrospective cohort study
Objective Blood urea nitrogen to albumin ratio (BAR) has served as a predictive marker for patients in the Intensive Care Unit (ICU), and has been studied in patients with sepsis, post-cardiac surgery...
Strategically creating maximally heterogeneous lab groups did not improve group performance in an introductory biology lab class
Collaboration is a critical skill for professionals in any field to master, and group work is a prominent component of many lab courses. However, there is conflicting guidance about the best method fo...
Microglia remodeling in the visual thalamus of the DBA/2J mouse model of glaucoma
Microglia are the resident immune cells of the central nervous system and mediate a broad array of adaptations during disease, injury, and development. Typically, microglia morphology is understood to...
Success and limitations in adaptation of Fast-TrACC tissue culture-independent transformation in coffee, cotton, and tree tobacco
Plant transformation is a critical process for generating transgenic and genome-edited plants for use in research and agriculture. For most plant species, this process has traditionally involved genom...
Financial market regulation and corporate social responsibility: Evidence from China’s new asset management regulation
This study explores how the financial market environment reshapes corporate social responsibility using a quasi-natural experiment provided by China’s New Asset Management Regulation. Our research foc...
Self-reported health, neuropsychological tests and biomarkers in fully recovered COVID-19 patients vs patients with post-COVID cognitive symptoms: A pilot study
Substantial numbers of individuals who contract COVID-19 experience long-lasting cognitive symptoms such as brain fog. Yet research to date has not compared these patients with healthy controls with a...
Prospective observational study of oxidative stress in the pathology of benign prostatic hyperplasia with bladder diverticulum
Background Oxidative stress contributes to benign prostatic hyperplasia (BPH) pathogenesis, but its role in BPH with bladder diverticulum is unclear. Methods This prospective cohort study compared 1...
Engaging boys as “Structured Allies” to prevent gender-based violence against girls: Results from the CARE Tipping Point Initiative in Nepal
Global efforts to end violence against women and girls (VAWG) include engaging men and boys. The CARE Tipping Point Initiative in Nepal engaged men and boys as structured allies in girl-centered movem...