PLoS ONE
Articles in this Issue
Temporal shifts in prognostic factors for 90- and 180-day outcomes after stroke thrombolysis: A machine learning analysis
Introduction Prognostication at 90 and 180 days after thrombolysis for acute ischemic stroke (AIS) is critical, yet the temporal evolution of key predictors remains inadequately un...
Fast-track pathway for giant cell arteritis: Improved visual outcomes and reduced healthcare costs
Background Giant cell arteritis (GCA) is the leading vasculitis threatening vision in adults aged ≥ 50 years; permanent vision loss may occur within the first few days after sympto...
Numerical simulation study of gas-solid two-phase flow characteristics in borehole sampling of coal cuttings
During the process of coal sampling through drilling and determining the gas content, the movement characteristics of coal particles within the borehole will affect the exposure time of the collected...
Urban Indian healthcare referral system: A qualitative exploration from the physicians’ perspectives
Background The Indian healthcare system continues to remain unstructured leading to sub-optimal health outcomes, not just in rural but even in urban areas. While physicians play a...
Limitations of multiexponential T1 mapping of cortical myeloarchitecture
Neuropsychiatric malignancies frequently manifest at the level of individual cortical layers. The resolutions currently available for medical magnetic resonance imaging (MRI) prevent the study of thes...
Lung infection in orally inoculated SARS-CoV-2 hamsters
The digestive tropism of SARS-CoV-2 due to the presence of the same ACE2 receptor in the digestive system as in the respiratory system raised the question of the role of fecal-oral transmission in the...
Correction: Role of immune-related endoplasmic reticulum stress genes in sepsis-induced cardiomyopathy: Novel insights from bioinformatics analysis
Stability of arterial blood gas samples after delayed analysis and mechanical stress
Purpose To investigate the effect of prolonged time before analysis and mechanical manipulation on pre-analytical stability of biomarkers and the validity of blood gas analysis res...
How surface texture affects consumers’ willingness to pay: Evidence from smartphone covers
This study investigates the impact of tactile impressions on consumers’ willingness to pay (WTP) for smartphone covers with varying surface textures. While prior research has examined visual and audit...
Effect of long-term use of treated wastewater and clean water mixtures on soil heavy metal accumulation: An assessment using pollution indices
The growing scarcity of clean water resources has driven increased interest in the use of treated wastewater (WW) as an alternative source for agricultural irrigation. While WW provides essential nutr...
Study on the health impacts of childhood asthma in China caused by air pollution
Asthma is one of the major disease burdens in children. Ambient air pollution is associated with the prevalence and exacerbation of childhood asthma. Over recent decades, China has exhibited a persist...
Trend and burden of ischemic stroke attributable to high body mass index in China from 1990 to 2021, with projection to 2044
Background Ischemic stroke (IS) poses a significant public health burden in China, with high body mass index (BMI) identified as a key risk factor. Despite this, the temporal trend...
Rapid purification of brain protein complexes containing active and inactive forms of the G protein Gαo
Gα o is the alpha subunit of the most abundant heterotrimeric G protein of the brain and relays signals from G protein-coupled receptors to inhibit neural funct...
Rational design of novel Plasmodium falciparum glutamyl-tRNA synthetase inhibitors for the development of next-generation antimalarial drugs
A major obstacle in treating malaria is the emergence of antimalarial drug resistance. The aminoacyl-tRNA synthetases (aaRSs), which are essential enzymes for protein synthesis, have been identified a...
Information about task duration influences energetic cost during split-belt adaptation and retention of walking patterns post-adaptation
Studies of locomotor adaptation have shown that adaptation can occur in short bouts and can continue for long bouts or across days. Information about task duration might influence the adaptation of ga...
Abnormal brain network reconfiguration in neuropsychiatric disorders across cognitive decline, Depression, and Schizophrenia
Objective Neuropsychiatric disorders are characterized by high complexity and comorbidity, imposing a substantial burden on both patients and society. However, their elusive pathog...
Feasibility and acceptability of using the BabySaver resuscitation platform and NeoBeat together for neonatal resuscitation in a low-resource setting: A pre-post implementation study
Background BabySaver and NeoBeat devices have the potential to enable bedside neonatal resuscitation, with an intact cord in the presence of the mother. We assessed the feasibility...
Violent deaths following disasters: A retrospective analysis
Introduction Negative mental health outcomes associated with disaster exposure can increase risks of interpersonal and self-directed violence. However, the link between disaster ex...
The Advanced Organ Support (ADVOS) hemodialysis system fulfills its intended purpose: Analysis of data from 282 patients from the Registry on Extracorporeal Multiple Organ Support (EMOS)
Several case series have highlighted the ADVOS hemodialysis system’s efficacy in eliminating water-soluble and protein-bound substances across diverse patient populations, such as multiorgan failure,...
Predicting economic activity using atmospheric nitrogen dioxide (NO2) satellite data: Evidence from local economic indicators in Japan
Accurate and timely measurement of subnational economic activity is crucial for policymakers during economic crises, natural disasters and pandemics such as COVID-19. The availability of such measurem...
Factors influencing the implementation of cardiopulmonary resuscitation among college freshmen: Based on the Theory of Planned Behavior
Objective Cardiac arrest is a leading cause of global mortality, for which timely cardiopulmonary resuscitation (CPR) is a critical intervention. However, public competence in CPR...
Dietary supplementation with Bacillus velezensis and Pichia guilliermondii improves growth performance through intestinal morphology and functionality enhancement in weaning piglets
The post-weaning period in piglets is often associated with significant changes in intestinal structure and function, which can negatively affect growth and performance. This study aimed to evaluate t...
Pharmacologic neuroprotective agents for the treatment of perinatal asphyxia in low-income and lower-middle-income countries: A systematic review and meta-analysis of randomised controlled trials
Background Perinatal asphyxia (PA) is a major contributor to neonatal mortality and long-term neurodevelopmental impairment, particularly in low- and middle-income countries (LMICs...
Object location memories recruit distal CA1 and catecholaminergic inputs to proximodistal CA1
The hippocampus is thought to combine “what” and “where” information from the cortex so that objects and events can be represented within the spatial context in which they occur. Surprisingly then, th...
Parents’ aversion to the possibility of having a gay or lesbian child predicts gendered parenting
Gendered parenting refers to parents’ tendency to raise their sons and daughters in accordance with gender stereotypes. Previous research showed that parents’ binary conceptions of gender are associat...