PLoS ONE
Articles in this Issue
Developing theory and evidence based intervention content using the Behaviour Change Wheel, Theoretical Domains Framework, and the Person-Based Approach: A worked example for an intervention targeting sedentary behaviour with people living with obesity
Introduction Both sedentary behaviour and obesity are independent risk factors for poor health and quality of life. Reducing sedentary behaviour is an important public health strat...
Classification of chronic pain and spinal cord stimulation response using machine learning in magnetoencephalography data
Background Due to the complexity of pain, involving physical, psychological, emotional and social aspects, we are still unable to objectively quantify or fully understand this subj...
The impact of a longitudinal mentorship program on medical students: A mixed-methods study
Background Mentorship is a critical element of medical education, shaping specialty preferences, professional identity, and confidence. At VinUniversity in Hanoi, Vietnam, the Long...
Spinal cord lesions in relapsing-remitting multiple sclerosis: Prognostic value of intrathecal production of immunoglobulins
Background Controversy exists about the radiological follow-up of the spinal cord in MS, since cord lesions are mostly symptomatic, but there are also reports that 10% − 25% are as...
Depression and anxiety mediate the relationship between COVID-19 stay-at-home orders and tobacco and marijuana use
Background The COVID-19 pandemic had notable impacts on the mental health of the U.S. population. There were concerns about how the pandemic affected substance use in the populatio...
Antimicrobial resistance profiles of bacteria from clinical specimens at Amhara Public Health Institute, Bahir Dar, Ethiopia: A retrospective study
Background Antimicrobial resistance is a major public health problem worldwide, particularly in developing countries. The effectiveness of currently available antimicrobial is decr...
The impact of hyperglycemia on prognosis in chronic obstructive pulmonary disease patients with coronary heart disease: A five-year prospective study
Background There is a lack of research on the impact of hyperglycemia on the prognosis of patients with both chronic obstructive pulmonary disease (COPD) and coronary heart disease...
Functional role of 18 LysR-Type transcriptional regulators of Salmonella enterica serovar Typhi
Salmonella enterica serovar Typhi ( S. Typhi) is the etiological agent of typhoid fever in humans. The genomic organization of this bacteriu...
Applying a new mold temperature control strategy to improve the tensile strength of thin wall products in injection molding processes
Mold temperature control critically influences injection molding, impacting product quality and production efficiency. High mold temperatures enhance surface quality but prolong cooling, increasing cy...
The SII-PNI score: A novel composite biomarker for personalized mortality risk prediction in peritoneal dialysis patients
Objective Accurate risk stratification is crucial for personalized management in peritoneal dialysis (PD). This study aimed to develop and validate a novel biomarker, the SII-PNI s...
Human-derived fecal virome transplantation (FVT) reshapes the murine gut microbiota and virome, enhancing glucose regulation
The gut microbiome, comprising bacteria, viruses, archaea, fungi, and protists, plays a crucial role in regulating host metabolism and health. This study explored the effects of fecal virome transplan...
Eye health in farmers: The impact of environmental and occupational factors
Farmers face higher health risks due to constant exposure to environmental and occupational hazards. Prolonged sun exposure increases the risk of UV-related eye damage (e.g., cataracts and pterygium),...
Optimizing solar irradiance forecasting: ANN models enhanced with ADAM and Cuckoo search algorithm
Renewable energy sources (RES) are being used and integrated into the electrical grid as a result of the environment’s effects and the ever-increasing demand for energy. Reliable and accurate forecast...
Motor-cognitive analysis of dual task walking in chronic obstructive pulmonary disease patients: An observational study using functional near infrared spectroscopy
Chronic Obstructive Pulmonary Disease (COPD), characterized by airflow limitation, commonly manifests cognitive and physical impairments that are often managed separately. The aim of this paper was to...
Synthesis, antimicrobial, antioxidant studies of thermally stable nanocomposite films doped with CoO-NPs for active food packaging applications
This research work presents a fabrication and study to explore different features of Gelatin/ Polyethylene glycol/ Chitosan ternary composite films doped with cobalt oxide nanoparticles. Such films we...
Co-regulation of microglial subgroups in Alzheimer’s amyloid pathology: Implications for diagnosis and drug development
Alzheimer’s Disease (AD) is a progressive neurodegenerative disorder and the leading cause of dementia. Neuroinflammation drives AD progression and therefore represents a promising target for diagnosi...
Circular RNA FTO functions as a hsa-miR-141-3p sponge to regulate the growth and migration abilities of human retinal endothelial cells via up-regulating ZEB1
Proliferative diabetic retinopathy (PDR) is a microvascular complication of diabetes mellitus. Circular RNAs have been implicated in the pathogenesis of PDR. This study aimed to elucidate the specific...
Creatine kinase and its muscle/brain isoenzyme as potential biomarkers for cardiovascular disease risk: A cross-sectional analysis of a population-based cohort
Introduction This study examines the correlation between creatine kinase (CK) and its muscle/brain isoenzyme (CK-MB) in relation to cardiovascular risk factors, highlighting sex di...
Single sperm karyotyping of testicular sperm in non-obstructive and obstructive azoospermia using next generation sequencing
The sperm of infertile men have higher rates of chromosomal abnormalities than those of fertile men. Miscarriage rate is also higher following testicular sperm extraction combined with intracytoplasmi...
Painting observation changes balance in patients with bilateral vestibulopathy
Background Bilateral vestibulopathy (BVP) is a disorder characterized by significant impairments in vestibular function, leading to changes in the kinematics of standing body sway....
Analysis of horizontal dynamic response of single pile under vertical load-Rayleigh wave combined action
In practical engineering, pile foundation will be subject to the combined action of vertical and Rayleigh wave, and the existence of vertical dynamic load will cause the second-order effect that will...
Benefits of psychosocial support for adolescent mothers on infant development and maternal mental wellbeing in Rakai and Kyotera, Uganda: Quasi-experimental study
Twenty-four percent of Ugandan women give birth before the age of twenty, which is the highest proportion in East Africa. Recent literature shows that 65% of the adolescent pregnancies in Uganda are u...
Impact of online lottery sales prohibition on the structure of lottery consumers: A time cost perspective in China
Lottery public welfare funds constitute a significant source of government fiscal revenue. Consequently, it is of crucial importance to objectively analyze the impact of purchasing convenience on the...
Nasopharyngeal carriage of Streptococcus pneumoniae, its associated factors, and antimicrobial susceptibility patterns among school children in Babile district, eastern Ethiopia
Background Streptococcus pneumoniae colonization is a growing concern globally, including in Ethiopia. School-aged children are a key r...
A digital twins-based policy simulation framework for rural photovoltaic entrepreneurship in China
Rural photovoltaic entrepreneurship in China faces critical challenges in aligning rapid technological advancements with lagging market responses, where 63% of technology adoption failures originate f...