PLoS ONE
Articles in this Issue
Temperature-humidity synergistic effects on predominant intestinal infectious diseases in Shenzhen, China: A predictive modeling framework for epidemiological early warning systems
The prevalence of intestinal infectious diseases (IIDs) in densely populated cities substantially escalates the burden of disease. An ecological study on the epidemiological trends of predominant IIDs...
Oxytocin administration during labor does not affect maternal serum oxytocin levels, early postpartum breastfeeding attitude and maternal attachment
The goal was to investigate the effects of synthetic oxytocin administration during labor on maternal and neonatal serum oxytocin levels, early breastfeeding attitudes, and postpartum maternal attachm...
Nano-curcumin enhances the sensitivity of tamoxifen-resistant breast cancer cells via the Cyclin D1-DILA1 axis and the PI3K/AKT/mTOR pathway downregulation
This research investigates the effects of nano-curcumin on the expression of Cyclin D1 and DILA1 genes, as well as on th...
Unravelling the therapeutic potential of dual TGFβ-1 and CXCR4 inhibition in breast cancer using computational strategies
Background and rationale The incidence and mortality of breast cancer (BC) continue to increase, making it a matter of public health concern worldwide. Despite the various strides...
Incidence and survival of Lung Cancer: A retrospective population-based cohort (Monastir, Tunisia: 2002–2022)
Introduction Lung cancer (LC) remains one of the most lethal malignancies worldwide. In Tunisia, LC population-level data is limited. This study aimed to estimate the incidence, mo...
Development and validation of a quantitative real-time PCR assay for the enumeration of Clostridium sporogenes in NaCl- and nitrite-reduced meat products
In the interest of enhancing consumer health and limiting the risks associated with excessive salt consumption and nitrosamine intake, there is an ongoing initiative to reduce the use of salt and nitr...
From attributes to value: Neural correlates of a front-of-package label on food decision-making – An fMRI study
Diet-related chronic illnesses, such as obesity and diabetes, pose major global health challenges. To promote healthier choices, policymakers have introduced nudges like front-of-package labels such a...
Phonological processing skills influence text-reading fluency in Russian-speaking adolescents
It is widely acknowledged that phonological processing skills are crucial for reading acquisition. While most research has focused on examining phonological processing in children, adolescents have re...
A GNSS receiver positioning algorithm based on weighting the statistical properties of discontinuous signals at lower rotation speeds
During relatively low-speed rotation, the receiver captures the signal only when the antenna is turned in the direction of the satellite due to the long signal loss, a process in which the signal may...
Development of an open-hardware semen homogenizer and application to serotonin effects on sperm motility
Proper homogenization of semen samples is crucial for assisted reproductive technology (ART) and analysis of sperm motility kinematics in experimental research. Accurate homogenization ensures a consi...
Origin of Mg-rich clay minerals in the first member of Maokou Formation in the middle Permian in the Central and Southern Sichuan Basin (China) and their implications on supergene and hypogene fluid regimes
The first member of Maokou Formation (MF1) in the Sichuan Basin is characterized by marl strata that serve as effective natural gas reservoirs. Notably, the development of MCMs (magnesium-rich clay mi...
A combined machine learning and finite element modelling tool for the surgical planning of craniosynostosis correction
Craniosynostosis is a medical condition that affects the growth of babies’ heads, caused by an early fusion of cranial sutures. In recent decades, surgical treatments for craniosynostosis have signifi...
Classification of LRS Bianchi-I spacetime in context of f(T) gravity via its self-similar symmetry
This study investigates self-similar vector fields of locally rotationally symmetric Bianchi type–I spacetimes within the framework of f ( T...
Mental health service delivery among adolescent girls and young women (AGYW) seeking HIV prevention and treatment services in central Kenya: A qualitative study of AGYW and healthcare providers’ perceptions
Introduction Common mental disorders (CMDs) are prevalent among adolescent girls and young women (AGYW) in high HIV-burden settings. However, mental health is underprioritized with...
Chloroplast genome analysis and phylogenetic position of Polygonatum sinopubescens and comparison with related species
The genus Polygonatum (Asparagaceae) comprises perennial herbaceous plants with significant economic and medicinal value. In this study, we analyzed the complet...
Internet fraud transaction detection based on temporal-aware heterogeneous graph oversampling and attention fusion network
This study proposes an advanced Internet fraud transaction detection method, the Temporal-aware Heterogeneous Graph Oversampling and Attention Fusion Network (THG-OAFN), designed to address the increa...
Biomechanical assessment of upright birthing positions using marker-based and markerless motion capture systems
Understanding the effects of birthing positions on labour is crucial for optimising maternal and foetal outcomes. Upright positions are encouraged but their biomechanics are not fully understood. Biom...
Trends in cognitive outcomes in middle-aged Americans across three birth cohorts
Middle age is a key life course period for targeting modifiable risk factors for late-life cognitive decline. Although the prevalence of chronic conditions that are risk factors for cognitive impairme...
Self-reported concussion prevalence, post-injury help-seeking behaviour, and associated risk factors among volleyball players
Background Volleyball is an under-researched sport, particularly in relation to risk factors for head impacts and sports-related concussion (SRC). This study aimed to estimate the...
Complications and oncologic outcome in bladder cancer patients receiving radical cystectomy after intravesical instillation treatment
Objective To evaluate the impact of previous intravesical treatment with Bacillus Calmette-Guérin (BCG) or mitomycin on postoperative complications and oncologic outcome in non-mus...
Availability and readiness of health facilities for non-communicable disease services in Ethiopia: Evidence from the nationally representative health facility survey 2022
Background In response to the escalating non-communicable disease (NCD) challenge, effective management of NCDs requires sustained investments in infrastructure, trained health wor...
Systematic analysis of non-melanoma skin cancer burden: A comparative study between China and the world from 1990 to 2021 and prediction to 2036
Objective To compare the characteristics and trends of the non-melanoma skin cancer (NMSC) burden in China and globally, and to provide a basis for the development of effective pre...
Manipulable preoperative factors affecting surgical outcomes of iStent inject W, particularly the type of antiglaucoma medications
To analyze the surgical outcomes of iStent inject W (ISIW) implantation and investigate the influence of preoperative factors. In total, 114 eyes of 114 patients (mean age, 73.22 ± 7.84 y) were enroll...
Nominal elastic modulus assessment in 3D-printed components under varying printing parameters using Bayesian methods and random forest surrogate modeling
The expanding range of materials available for 3D printing is driving its widespread adoption in advanced fields. As 3D printing becomes increasingly prevalent in the manufacturing of industrial compo...