PLoS ONE
Articles in this Issue
Bearing fault diagnosis method based on enhanced VMD and adaptive-optimized SDAE
Motor rolling bearing is a fundamental component of industrial production, and its vibration signal extraction and fault diagnosis are challenging because of the effect of operating characteristics an...
A blended modeling framework for real-time design and verification of safety-critical embedded systems
Embedded systems often require multiple representations for design, verification, and implementation, ranging from low-level programming languages to high-level formal models and domain-specific abstr...
Decoding brand sentiments: Leveraging customer reviews for insightful brand perception analysis using natural language processing and Tableau
Traditional survey-based feedback has given way to real-time online reviews, yet transforming this unstructured text into actionable knowledge remains difficult. Focusing on the highly competitive sma...
Where to invest in neonatal survival programs in Nepal? A modelling study using Lives Saved Tool through scaling key interventions
Background Neonatal survival remains a major public health priority in many low and middle-income countries including Nepal, where the neonatal mortality rate (NMR) is 21 per 1,000...
Renal and hepatic function is preserved following inducible knockout of kynurenine pathway enzymes KMO or QPRT in adult mice
The kynurenine pathway (KP) is the canonical route by which tryptophan is metabolised, almost all of which occurs in the liver, with significant expression of its enzymes also known in the kidney. We...
Effects of cotton straw biochar on methane emissions using rumen simulations
Context Cotton stalk valorization is limited by high lignification, resulting in waste and environmental issues. Biochar, a pyrolysis-derived material, shows promise in reducing ru...
Tardiness hair in transitional zone: Analysis between age and frontal forehead hairline in children aged below 5 years old
Objective This study aimed to investigate the morphological characteristics and distribution of frontal hairline patterns among Chinese infants and young children aged 0–5 years an...
Temperature-mediated shifts in feeding behaviour and metabolism in an omnivorous rock pool prawn
Temperature is a key factor influencing metabolic processes and ecological interactions in ectothermic organisms, and can determine pathways of energy flow in food webs. In this study, we tested the h...
Forced oscillation response of the dynamic surface tension of molten titanium
Background This study employed the molecular dynamics simulation method to systematically investigate the dynamic response behavior of the molten titanium liquid-vapor interface un...
Harnessing technology in education: The function of RIPPLES model in ICT utilization in public secondary schools of Amhara, Ethiopia
This study examined factors influencing the utility of ICT in enhancing teaching and learning effectiveness in secondary schools in the state of Amhara, Ethiopia. It specifically explored the effects...
Artificial intelligence based personalized student feedback system -Sisu Athwala’ to enhance exam performance of medical undergraduates
Background In medical education, mentoring and feedback play crucial roles. Providing feedback on exam performance is a vital component as it allows students to improve. Feedback h...
Lysine p-nitroanilide impairs cellular energetics and potentiates statin-induced cytotoxicity in RD rhabdomyosarcoma cells
Statins are clinically effective drugs for treating dyslipidemia and have been proposed as promising antineoplastic and adjuvant agents in cancer therapy for years due to their impact on dysregulated...
A feature recognition and detection algorithm for pine wilt disease trees based on FLMP-YOLOv8
Pine wilt disease, a highly contagious forest disease caused by the pine wood nematode and primarily transmitted via its insect vector, the pine sawyer beetle (Monochamus spp.), poses a significant th...
Influence of inter-fractional respiratory motion changes on dose delivery accuracy in dynamic conformal arc lung stereotactic body radiotherapy: A phantom study
Purpose To evaluate the influence of inter-fractional respiratory motion variation on dose delivery accuracy in dynamic conformal arc lung stereotactic body...
Central obesity rather than BMI is associated with chronic pain: A cross-sectional analysis of NHANES
Background Chronic pain is a prevalent and debilitating condition that poses a major public health burden. Most existing research on obesity and pain has focused on general obesity...
Polypharmacy and frailty among aging World Trade Center responders
Background During and after the 9/11 rescue and recovery efforts, World Trade Center (WTC) responders were exposed to environmental hazards that may accelerate aging and increase f...
Morphological diversity in the honeyeater hyolingual apparatus and its relationship with nectarivory
Honeyeaters (Aves, Meliphagidae) are a speciose clade of nectarivorous birds, and there is immense diversity in the degree to which different species within the family rely on nectar. Honeyeater tongu...
Correction: Automatic detection of expressed emotion from five-minute speech samples: Challenges and opportunities
Use of a new micropattern tape method to detect chirality shifts in differentiating C2C12 cells
Chirality is an intrinsic property of cells manifested as left-right (LR) asymmetry in terms of cellular morphology and organization, which influences cell behavior, migration, and tissue development....
Characterizing rurality using the All of Us Research Program data
Rural communities experience disproportionately higher rates of chronic diseases, less access to healthcare services, and poorer health outcomes compared to their urban counterparts in the United Stat...
Evolutionary dynamics of value co-creation within the industry-university-research network: A multi-agent game perspective
This paper investigates the evolutionary dynamics of value co-creation and defines the roles of multiple agents within the industry-university-research (IUR) network. A distinctive evolutionary game m...
Non-muscle myosin IIC predominantly expressed in the slow-twitch skeletal muscles impedes age-related muscle weakness
Skeletal muscle expresses three types of non-muscle myosin (NM) II in addition to skeletal type myosin. While immature myoblasts have been reported to express NMIIA and NMIIB, playing roles in cell mo...
Comprehensive analysis platform to understand, remedy, and eliminate amyotrophic lateral sclerosis (CAPTURE ALS): Study protocol for a Canadian multicenter, multimodal, longitudinal observational study
Background The marked heterogeneity of Amyotrophic Lateral Sclerosis (ALS) combined with a lack of biomarkers are key contributing factors to the lack of disease-modifying treatmen...
The role of active inference in conscious awareness
Active inference, a first-principles framework for modelling the behaviour of sentient agents, is beginning to be applied in consciousness research. One hypothesis arising from the framework is that a...
Impact of anodal tDCS and virtual reality on cognitive dysfunction in patients with Multiple Sclerosis: Protocol of a double blind, randomized, prospective, controlled study
Background Cognitive impairment (CI) affects a significant proportion of people with Multiple Sclerosis (PwMS), even in the early stages of the disease, increasing fatigue percepti...