PLoS ONE

Vol. 20, Issue 12 Issue 12 2025
1540
Articles

Articles in this Issue

A study protocol to explore the effectiveness and implementation of mobile community outreach services for women who use drugs in Baltimore, Maryland: The SHOUT Study

Sewika Sulpe, Catherine Tomko, Emily Clouse et al. Dec 01, 2025 pp. e0336607 10.1371/journal.pone.0336607

The opioid overdose crisis has continued to affect women who use drugs (WWUD), particularly in urban cities such as Baltimore, Maryland, where fatal overdose rates rank among the highest in the nation...

HLA-B*44 is associated with a more than twentyfold increase in cyclic citrullinated peptide antibody serum level in Croatian patients with seropositive rheumatoid arthritis

Jure Aljinović, Darko Kero, Daniela Šošo et al. Dec 01, 2025 pp. e0334551 10.1371/journal.pone.0334551

Objectives To determine whether any of the HLA-A*, HLA-B* and HLA-DR* alleles in seropositive rheumatoid arthritis (RA) can be associated with the extreme serum levels of rheumatoi...

Study on the performance of Type II vertical rescue timber shores based on experiment and simulation

Feng Zhang, Xiangyang Lu, Hao Zhang Dec 01, 2025 pp. e0337699 10.1371/journal.pone.0337699

Structural instability poses significant risks at earthquake rescue sites, where Type II vertical timber shores play a pivotal bridging role in rapidly securing operational space safety. To systematic...

Performance optimization and mechanism study of asphalt mixtures modified with ZM additive

Yining Wang, Weishuai Ji Dec 01, 2025 pp. e0337535 10.1371/journal.pone.0337535

To enhance the high-temperature stability, low-temperature crack resistance, moisture susceptibility, and fatigue life of asphalt mixtures, this study systematically investigates the effects of Zhongm...

RETRACTED: Natural gas price prediction based on artificial intelligence models

Xuhui Liu, Meiqi Tang, Yu Feng et al. Dec 01, 2025 pp. e0336582 10.1371/journal.pone.0336582

The natural gas supply crisis triggered by the Russia–Ukraine conflict has laid bare the energy market’s extreme vulnerability in the face of geopolitical risk, highlighting the need for accurate mult...

Mechanistic insight into the antidiabetic effects of Ficus hispida fruits: Inhibition of intestinal glucose absorption and pancreatic beta-cell apoptosis

Nusaiba Jahan, Noimul Hasan Siddiquee, Rifayat Ara Khanom Riva et al. Dec 01, 2025 pp. e0337465 10.1371/journal.pone.0337465

The worldwide health impact of Type 2 diabetes mellitus (T2DM) is marked by the dysregulation of glucose metabolism caused by α-glucosidase-mediated carbohydrate degradation and pancreatic β-cell apop...

Distribution and characteristics of rearranged hopanes in the black shale of the Chang 9 member, the Upper Triassic Yanchang Formation in the Ansai area, Ordos Basin, North China

Han Yue, Yan Liu, Rongxi Li et al. Dec 01, 2025 pp. e0337076 10.1371/journal.pone.0337076

Shale samples from source rocks of the Upper Triassic Yanchang Formation (Chang 9 member) in the Ansai area, Ordos Basin, North China, were analyzed using gas chromatography – mass spectrometry (GC-MS...

Retraction: Exploring the impact of renewable energy on economic growth and carbon emissions: Evidence from partial least squares structural equation modeling

Dec 01, 2025 pp. e0337857 10.1371/journal.pone.0337857

Potential phosphorylation of Liprin-α1 at threonine 701 regulates integrin-mediated cell motility

Martina Ramella, Daniele Brambilla, Sara Surini et al. Dec 01, 2025 pp. e0337621 10.1371/journal.pone.0337621

A dynamic protein network at the leading edge of motile cells is needed to coordinate events required for efficient cell motility. Previous work has shown that the Ser/Thr kinase DYRK3 affects the ass...

Correction: Genomic and bioacoustic variation in a midwife toad hybrid zone: A role for reinforcement?

Johanna Ambu, Christophe Dufresnes Dec 01, 2025 pp. e0337571 10.1371/journal.pone.0337571

Identification of key genes associated with idiopathic pulmonary fibrosis and sarcopenia by bioinformatics analysis

Lanying Shen, Zihan Yi, Jiahao Liu et al. Dec 01, 2025 pp. e0335067 10.1371/journal.pone.0335067

Background Idiopathic pulmonary fibrosis (IPF) and sarcopenia significantly affect patients’ quality of life. The progression and worsening of these conditions are often associated...

Post-quantum-inspired scalable blockchain architecture for internet hospital systems with lightweight privacy-preserving access control

Lulu Hao, Ruoyu Wang, Xiaofeng Wang et al. Dec 01, 2025 pp. e0332887 10.1371/journal.pone.0332887

The increasing adoption of Internet hospital systems—enabled by the real-time data streaming capabilities of the Internet of Medical Things (IoMT)—has intensified the need for secure, scalable, and lo...

Expression of concern: Enhancement of auranofin-induced apoptosis in MCF-7 human breast cells by selenocystine, a synergistic inhibitor of thioredoxin reductase

Dec 01, 2025 pp. e0337853 10.1371/journal.pone.0337853

Innovative design and evaluation of medical nebulizer for preschool children: A user demand-driven approach

YanXiao Zhao, Tao Wang, Liming Zhang et al. Dec 01, 2025 pp. e0325199 10.1371/journal.pone.0325199

Aims To enhance the user experience and satisfaction of children’s medical nebulizers, and to improve adherence and the efficacy of nebulization treatments for children, this study...

Evolutions of partner-ruled surfaces with simultaneous inextensibility conditions

Kemal Eren, Soley Ersoy, Mohammad Nazrul Islam Khan Dec 01, 2025 pp. e0336149 10.1371/journal.pone.0336149

Ruled surfaces are a class of surfaces generated by a moving straight line and are used in various design and modeling applications, including kinematics, robotics, and computer-aided geometric design...

Integrated single-cell RNA-seq and bulk RNA-seq analysis to investigate key adipogenesis genes in adipose-derived stem cells

Tongtong Zhang, Zhongming Cai, Haoran Li et al. Dec 01, 2025 pp. e0335152 10.1371/journal.pone.0335152

Adipogenic differentiation of adipose-derived stem cells (ADSCs) is fundamental to both adipose tissue homeostasis and clinical applications, particularly fat grafting. However, the global and stage-s...

Retraction: Machine vision model for drip leakage detection of pipeline

Dec 01, 2025 pp. e0337862 10.1371/journal.pone.0337862

The effect of ergometer cycling and visual foraging on brain function: A pilot study

Tamara S. Dkaidek, Amelia Dingley, Justin Parsler et al. Dec 01, 2025 pp. e0336642 10.1371/journal.pone.0336642

Dual-task training comprising cognitive and physical components may enhance cognitive function, and increased prefrontal cortex activation may underpin these improvements. The aim of this pilot study...

Psychometric network analysis reveals how sensory processing relates to self-reflection traits in adolescence

Lisa Raoul, Marie-Hélène Grosbras Dec 01, 2025 pp. e0335259 10.1371/journal.pone.0335259

While recent research links sensory processing to mental traits, this has scarcely been explored in adolescence, a period characterized by changes in self-reflection and onset of mental disorders. Thi...

Protocol for a randomized controlled trial of a combined motivational interviewing and behavioral couples therapy intervention to reduce intimate partner violence and alcohol use in south India

Meghna Achar, Megan Ramaiya, Krishnamachari Srinivasan et al. Dec 01, 2025 pp. e0335332 10.1371/journal.pone.0335332

There is a strong association between alcohol use disorder (AUD) and intimate partner violence (IPV), both widely prevalent global health issues. However, few interventions target both IPV and AUD, in...

Demographic trends and disparities among NIH-funded medical school faculty in the US, 1970–2022

Alyssa Browne Dec 01, 2025 pp. e0337610 10.1371/journal.pone.0337610

Background Although gender and racial/ethnic trends and disparities are well documented among recipients of National Institutes of Health (NIH) research grant funding, little is kn...

Visit-to-visit glycemic variability is associated with lung function variables and lung function impairment in individuals with type 2 diabetes

Yi-Hua Wu, Chia-Ing Li, Chiu-Shong Liu et al. Dec 01, 2025 pp. e0337885 10.1371/journal.pone.0337885

Glycemic variability (GV) is an emerging biomarker of glycemic control and may be a predictor for lung function impairment in persons with type 2 diabetes mellitus (T2DM). However, the associations be...

From safety commitment to safety behavior: The mediating role of safety awareness

Shanshan Lu, Weiwei Zhu, Li Zhang et al. Dec 01, 2025 pp. e0332080 10.1371/journal.pone.0332080

To deeply analyze the mechanism of workplace safety climate on employee safety behavior, a conceptual model of employee safety behavior was constructed based on the theory of stimulus-organism-respons...

Integrated multi-omics analysis reveals necroptosis-related biomarker BIRC3 for early diagnosis and therapeutic targeting in preeclampsia

Qingxia Lin, Peifeng Huang, Youhong Kang et al. Dec 01, 2025 pp. e0337546 10.1371/journal.pone.0337546

Background Preeclampsia (PE) is a life-threatening pregnancy disorder lacking reliable early biomarkers. While apoptosis is implicated in PE pathogenesis, the role of regulated nec...

Exploring spatial variation and multilevel modeling of malaria prevalence among children aged 6-59 months based on RDT in Niger: Insights for public health decision-making

Solomon Sisay Mulugeta, Bezanesh Melese Masresha, Legesse Alamerie Ejigu Dec 01, 2025 pp. e0336022 10.1371/journal.pone.0336022

Background: Malaria is a life-threatening infectious disease caused by parasites of the genus Plasmodium transmitted through the bite of infected female Anophel...

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Journal Info

Publisher Public Library of Science
ISSN 1932-6203
Subject Health Sciences
Language English
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