PLoS ONE
Articles in this Issue
Bioassay-guided fractionation and identification of wound healing active compounds from Khaya senegalensis leaves
This study investigated the wound healing potential of Khaya senegalensis leaves through a comprehensive approach, including phytochemical, antioxidant, cytotox...
Eight-Port millimeter wave MIMO antenna loaded with novel frequency selective surface for higher data rate transmission
In this research, an eight-port multiple-input-multiple-output (MIMO) antenna integrated with frequency frequency-selective surface (FSS) is presented for 28.0 GHz millimeter-wave (n257/n261) bands. T...
Comparative study on the kinetic model and effect of sludge protein dissolution under the synergistic action of acid-thermal and alkaline-thermal
Risk of prostatitis in patients with type 2 diabetes mellitus: An observational retrospective cohort study of canagliflozin versus other antihyperglycemic agents using propensity score matching
Purpose Prostatitis has been reported in patients with type 2 diabetes mellitus (T2DM) receiving antihyperglycemic agents (AHAs). This study was conducted to evaluate the risk of p...
ViT-Stain: Vision transformer-driven virtual staining for skin histopathology via global contextual learning
Current virtual staining approaches for histopathology slides use convolutional neural networks (CNNs) and generative adversarial networks (GANs). These approaches rely on local receptive fields, stru...
How digital transformation curb greenwashing: Insights from fraud risk factor theory
This study investigates how digital transformation influences corporate greenwashing and promotes genuine sustainable development, drawing on the framework of fraud risk factors. Based on panel data f...
Mining the FAERS database reveals new safety signals for 120 mg denosumab in oncology practice
Objective To detect and quantify adverse drug event (ADE) signals linked to 120 mg denosumab in the real world. Methods...
Genetic diversity, phylogeography, population structure, and demographic history of wild Catla catla at a transboundary scale across South Asia revealed by Mitochondrial COI sequences
This study presents the first assessment of mitochondrial cytochrome c oxidase I (COI) sequences from multiple countries to evaluate the genetic diversity, phylogeographic relationships, population st...
In sickness and health: A reflexive thematic analysis of ethical considerations and experiences of owners of cats treated for diabetes mellitus
Cats are widely regarded as beloved family members, with whom owners develop strong emotional bonds. When a cat is diagnosed with diabetes mellitus, many owners choose to pursue medical treatment desp...
Optimization, characterization and biological activity of siderophore produced by marine Streptomyces coelicolor
Two Streptomyces spp. were isolated from open ocean waters of the Gulf of Mannar. Of the two isolates, one was identified as...
The effects of human training data (HTD) explanation on purchase intention for artificial intelligence (AI) technologies
Consumers exhibit resistance to Artificial Intelligence (AI) technologies despite their widespread deployment. One common thread linking various reasons for this is the perceptions of AI technologies’...
Loss of IL1RA promotes prostate cancer growth and metastasis by activating Akt signaling pathway
Background. Interleukin-1 receptor antagonist (IL1RA) blocks the interaction between IL-1 and its receptors. It modulates inflammatory responses, cell proliferation, and the invasi...
Wall-L merge sort: A tunable and adaptive sorting algorithm for diverse computing environments
Sorting algorithms play a crucial role in computing, but most are designed with rigid structure that are only efficient under certain conditions. Although some sorting algorithms perform well in some...
Synergistic anti-icing and snow-melting performance of two-component road markings enabled by PCMs and slow-release salts
Conventional road marking coatings suffer significant performance deterioration under winter conditions, including frost coverage, reduced retroreflectivity, and low-temperature embrittlement. This st...
Predictors of exclusive breastfeeding among infants under-six months in rural Ethiopia
Background Exclusive breastfeeding (EBF) is the practice of providing infants with only breast milk for the first six months of their life, except for medically prescribed drugs or...
Relationships among fertility concerns, fear of cancer recurrence, social support, self-efficacy, and family resilience among Chinese adolescents and young adults with cancer: A structural equation modeling
Fertility concerns, fear of cancer recurrence, social support, and self-efficacy are key factors that influence family resilience in adolescents and young adults with cancer. However, their combined e...
Boosting brain tumor segmentation: A novel 3D pooling approach with U-net 3D
Brain tumor segmentation is a crucial task in medical imaging that has a significant impact on diagnosis and treatment planning. This study introduces a novel 3D pooling layer within the U-Net 3D arch...
Intratumoral spatial heterogeneity at non-contrast CT predicts histological grading of invasive pulmonary adenocarcinoma: a multicenter retrospective study
Objectives The International Association for the Study of Lung Cancer (IASLC) grading system is key to the prognosis and treatment of Invasive Pulmonary Adenocarcinoma (IPA). Howev...
Autapses enable temporal pattern recognition in spiking neural networks
Most sensory stimuli are temporal in structure. How action potentials encode the information incoming from sensory stimuli remains one of the central research questions in neuroscience. Precise spike...
Structural damage detection and safety assessment method based on machine vision and machine learning
Structural damage detection and health assessment are crucial for maintaining infrastructure safety and durability. This study presents a novel multi-scale vision-based framework that combines deep le...
Iodine increases pulmonary type I interferon responses and decreases covid-19 disease severity: Results from an open label randomized clinical trial
Objective To investigate whether oral treatment with 12.5 mg iodine additional to standard of care is effective in reducing mortality and clinical deterioration of patients hospita...
The between competition sprint profile of intercounty female gaelic football during training and match-play: An exploratory study
Female Gaelic football is an invasive field-based team sport but there are limited data on players’ sprint profiles. This study aimed to examine between-competition (league vs championship) difference...
Pharmacists’ perspectives on implementing pharmacist-managed anticoagulant clinics in Makkah Region Ministry of Health Hospitals: A qualitative study
Objectives This study aimed to identify the pharmacists’ perspectives on the barriers and facilitators to implementing pharmacist-managed anticoagulation clinics (PMACs) in Ministr...
Satellite-derived temperature measures miss key physiologically relevant thermal trends on Palauan reefs
Coral reefs are important both economically and culturally to over 1 billion people. However, reefs continue to be threatened by climate change, with some areas now experiencing mass coral bleaching a...
Mechanical power and short-term mortality in critically ill patients with ARDS on mechanical ventilation: Insights from the MIMIC-IV database
Mechanical power (MP), or an integrated measure of ventilatory stress, has been proposed as an important determinant of ventilator-induced lung injury and clinical outcomes. However, its prognostic si...