PLoS ONE
Articles in this Issue
Research on the evolution of physical teachers and physical teaching policy: A perspective from China
This study aims to comprehensively and profoundly explore the history of changes in China’s physical teachers and physical teaching policies. Focusing on policies related to physical teachers and teac...
Generalized FitzHugh-Nagumo equations with Caputo gH-differentiability: A novel fuzzy fractional approach to digital memristor networks
The fuzzy fractional generalized FitzHugh-Nagumo differential equations (FFGFH-NDEs) is a well-known and generalized model that plays a significant role in biological systems, including complex synchr...
Evaluation of a mobile-based remote aftercare application in cochlear implant users
Introduction Clinical follow-up for cochlear implant (CI) users is typically carried out in a face-to-face session in a clinical site. Users must travel to the site, which incurs b...
Regional political climate’s moderating role in the association between political conservatism and COVID-19 vaccine hesitancy in the United States
There is an emerging body of evidence linking political conservatism and conservative political climate in the United States to COVID-19 vaccine hesitancy and uptake. The goal of the present research...
The impact of simultaneous batch turn downs and targeted kidney utilization decisions on patient survival
In the US, Organ Procurement Organizations (OPOs) procure deceased-donor kidneys, whereas Transplant Programs (TxPs) make utilization decisions for candidates listed at their centers. For each donor,...
Association of tissue lymphocyte immunophenotype and clinical outcomes: A prospective study in patients with ulcerative colitis treated with vedolizumab
Introduction Vedolizumab binds to α4β7 integrin, thereby inhibiting lymphocyte migration into the gastrointestinal tract. It is used to treat moderate to severe ulcerative colitis...
Expression of Concern: Effects of Ramadan fasting on aspirin resistance in type 2 diabetic patients
Understanding contraceptive use in Pakistan: The role of individual and community contextual factors
Key findings from the PDHS 2017−18 indicate that the total demand for family planning among married women in Pakistan was 52%. Research is needed to understand the persistently low contraceptive use i...
Research on the power of non-state-owned shareholders in the board and state-owned enterprises’ innovation investment
In the deepening stage of the reform of mixed ownership of state-owned enterprises from “mixed equity” to “reform mechanism”, how to stimulate the vitality of enterprise innovation through effective r...
Machine learning for the diagnosis of fibromyalgia based on magnetic resonance imaging
The clinical diagnosis of fibromyalgia (FM), a syndrome characterized by generalized pain, is challenging due to its unknown etiology and frequent comorbidity with other diseases. As a noninvasive mod...
Thoracic surgeons’ practice and attitude towards surgical antimicrobial prophylaxis in VATS lung surgery: A survey within a large medical consortium
Background and objectives Surgical site infections (SSIs) are a significant post-surgery complication, impacting mortality, morbidity, and healthcare costs. Surgical antimicrobial...
A hybrid color emotional experience approach: Integrating the pleasure-arousal-dominance model with fuzzy grey relational analysis
Color schemes are a crucial component of modern product design and user experience, closely linked to users’ emotional needs. However, emotional experiences with product colors are inherently complex...
Skin-related adverse events and their associated factors among Diabetic patients on insulin therapy
Background More than 530 million individuals globally are afflicted with diabetes mellitus (DM), and the prevalence continues to escalate. Insulin remains the cornerstone of DM man...
Temporal trends and health inequalities in global, regional, and national years lived with disability of severe periodontitis from 1990 to 2021
This study evaluates changes in cross-national disparities in the burden of severe periodontitis between 1990 and 2021. All data on severe periodontitis used in this study were derived from the 2021 G...
Model-free prognostication of non-linear time series
Objective The COVID-19 pandemic has highlighted the importance of studying the course of infectious progression. Similar needs exist for time series of other origins. While models...
Virological failure and risk factors among people living with HIV taking second-line ART in Addis Ababa, Ethiopia
Background Virological failure (VF) presents significant challenges in the emergence of drug resistance, and elevated risk of transmission, higher mortality rates, and a diminished...
Making community-based health planning and services work: Staffing, accountability and digital integration for quality primary health care in Northern Ghana
Background Strengthening primary health care through Ghana’s Community-based Health Planning and Services (CHPS) strategy depends on functional community structures, responsiveness...
In-silico characterization of deleterious non-synonymous SNPs in the human S1PR1 gene reveals structural instability and altered ligand affinity
S1PR1 is a G protein-coupled receptor that plays a key role in regulating lymphocyte trafficking, immune response, cardiovascular system function, cell proliferation and survival, tumor angiogenesis,...
A fractional-order approach to predator-prey interactions: Modeling fear and disease dynamics with memory effects
The dynamical behaviors of a predator-prey model with fear effect and disease on prey are studied by employing the fractional-order derivative with a power-law kernel as the operator. The proposed mod...
Complex excitability and “flipping" of granule cells: An experimental and computational study
In response to prolonged depolarizing current steps, different classes of neurons display specific firing characteristics (i.e., excitability class), such as a regular train of action potentials with...
Evidence of prevailing practice of home slaughter in Iran revealed by bioeconomic modeling of small ruminants slaughtered in and outside registered abattoirs
Home slaughter seems to be a prevailing practice in developing countries, and presents a potential public health risk and animal welfare problem for the societies all over the world. Nevertheless, the...
The association between long-term opioid therapy and composite infection-related dental outcomes
Background The Food and Drug Administration’s warning that transmucosal buprenorphine, a partial opioid agonist used to treat opioid use disorder and chronic pain, may cause dental...
Study of element concentrations in blood serum of patients receiving parenteral nutrition using total reflection X-ray fluorescence analysis
Total reflection X-ray fluorescence (TXRF) analysis was used to determine element concentrations in blood serum samples of patients receiving parenteral nutrition. The concentrations of elements were...
Mediating effect of smoking abstinence self-efficacy on association between health literacy and nicotine dependence of smokers in Qingdao, China
Objective Research on the mediating effect of smoking abstinence self-efficacy (SASE) on the relationship between health literacy and nicotine dependence is limited. This study exa...
The novel mineralocorticoid receptor modulator balcinrenone protects against diet-induced cardiac microvascular dysfunction and plasma potassium elevation in mouse models
Overactivation of the mineralocorticoid receptor (MR) promotes tissue remodeling in patients with heart failure (HF) and/or chronic kidney disease (CKD). These patients may benefit from MR antagonists...