PLoS ONE
Articles in this Issue
Defining frailty using a modified Fried’s Frailty Phenotype in a Southern African context
Introduction Frailty leads to disability, morbidity, and mortality in older persons. The Fried’s Frailty Phenotype (FFP), derived in the American Cardiovascular Health Study (CHS),...
Retraction: Interpretable machine learning framework for predicting Urban air quality
Identification of common genes and biomarkers between Dermatomyositis and rheumatoid arthritis through integrated bioinformatics
Background Dermatomyositis (DM) and rheumatoid arthritis (RA) share immuno-inflammatory features, yet mechanisms underlying their comorbidity remain unclear. We aimed to define sha...
Expression patterns of bone morphogenetic protein 7 (BMP7) and its prognostic roles in neuroblastoma: An integrated bioinformatics analysis
Background Bone morphogenetic proteins (BMPs) are associated with the prognosis of various types of adult cancers. However, the expressions and prognosis of BMPs in pediatric neuro...
Effects of fermented Rosa roxburghii Tratt pomace on growth performance, lipid metabolism, antioxidant activity, and amino and fatty acid profile in goats
Rosa roxburghii Tratt pomace, is a juice extraction rich in polyphenols with strong antioxidant activity. The objective of this study was to evaluate the effect of fermented...
Effects of digital game-based learning as a tool for laparoscopy training in surgical nursing
Background The present study aimed to (1) develop a digital game focusing on the roles of surgical nurses (scrub and circulator nurses) in laparoscopic surgeries, (2) conduct a ran...
Correction: Delayed hepatic response and impaired cytokine dynamics in aged mice following burn injury: Implications for elderly patient care
Spatial analysis of mortality due to congenital syphilis in Brazil from 2008 to 2022
The objective of this study is to analyze spatial distribution of mortality due to congenital syphilis in Brazil from 2008 to 2022. This is an ecological study that considered congenital syphilis deat...
Correction: Recovery and partial isolation of α-mangostin from mangosteen pericarpsvia sequential extraction and precipitation
Disproportionality analysis of drug-associated progressive multifocal leukoencephalopathy using spontaneous reports: A 20-year signal detection study based on the FAERS database
Background Progressive multifocal leukoencephalopathy (PML) is a rare, often fatal demyelinating disease caused by JC virus reactivation in immunocompromised patients. With the inc...
Diet and stones: Associations from a large, population-representative study of urolithiasis and renal colic-like pain symptoms in Poland
Introduction Urolithiasis and renal colic-like pain symptoms are prevalent conditions influenced by many factors, including diet. Regional assessments, particularly in culturally d...
Pigs and pasture: Drivers and characteristics of outdoor systems on the island of Ireland
Outdoor systems offer benefits to pig welfare but they also pose challenges and are less well researched than indoor. This study characterized, for the first time, current husbandry and management pra...
Maternal knowledge and practice of safe infant sleep position in South Ethiopia: Implications for preventing sleep-related infant deaths
Background Safe infant sleep position practice is crucial for infants from birth to 12 months of age. One of the most important interventions in infancy is choosing the right sleep...
A multidimensional procurement literacy instrument: Development and validation among undergraduate procurement students in Ghana
Procurement remains one of the central functions in public- and private sector governance, yet relatively little attention has been given to how procurement capabilities develop during undergraduate e...
Machine learning-based prediction of acute and complicated appendicitis using readily available data in low-resource settings
Background Acute appendicitis often presents diagnostic challenges, especially in pediatric and elderly patients. Delays can cause serious complications. While imaging aids diagnos...
The influence of stigma on PrEP uptake among adolescent girls and young women in Johannesburg, South Africa and Mwanza, Tanzania: Qualitative findings from the EMPOWER study
Background Adolescent girls and young women (AGYW) in sub-Saharan Africa need HIV prevention options. Stigma may impede uptake and consistent use of oral pre-exposure prophylaxis (...
Correction: Impact of frailty and its change on urinary incontinence: A longitudinal analysis from two prospective study of ageing
Ischemic preconditioning enhances energy supply during frequency speed kick test in Taekwondo athletes: A randomized crossover study
Purpose This study aimed to examine the effect of ischemic preconditioning (IPC) on energy supply during sport-specific tests in male taekwondo athletes. To our knowledge, this is...
Facilitators and barriers of physical activity, sedentariness and exercise adoption among healthcare professionals in Lagos State, Nigeria – A qualitative review
Physical inactivity is a major global public health concern, identified by the World Health Organization as the fourth leading cause of mortality worldwide and associated with an estimated 3.2 million...
Overweight and obesity association with mortality in patients with heart failure and reduced or preserved ejection fraction-a cohort study
Background Obesity is a risk factor for incident heart failure, but patients with excess weight and heart failure have lower mortality. This “obesity paradox” may be explained eith...
Path planning for UAVs in complex terrain based on the PGD model: Algorithmic improvements combining feature extraction and reinforcement learning
This paper proposes the PGD model for UAV path planning in complex terrain, addressing key challenges such as high-dimensional state processing, blind path exploration, and poor cross-scene adaptabili...
Exploring phonological complexity in statistical learning of artificial words
Purpose This study examined whether phonological complexity enhances auditory word learning within a statistical learning framework. Specifically, we tested if exposure to phonolog...
Soil environment effects on the occurrence of black sesame spot and clubroot disease in Chinese Cabbage
Chinese cabbage is a popular leafy vegetable widely consumed in Asian cuisine, particularly in China. However, it is susceptible to various diseases, including clubroot and black sesame spot, which ca...
An intelligent control algorithm for gas precise drainage problem based on Model Predictive Control
Intelligent extraction of coal seam gas constitutes a crucial development direction for managing underground gas disasters. Building on an established mathematical model, this study develops an intell...
Impact of African swine fever emergency on the mental health of first responders in the Dominican Republic
African swine fever (ASF) has become a global pandemic, affecting nearly 2 million pigs since 2022 alone and causing significant disruption to food security and trade. The Dominican Republic (DR) has...