PLoS ONE
Articles in this Issue
The association between parental resilience and emotional/behavioural problems in children with autism spectrum disorders: The mediating role of parenting style
Parental psychological resilience plays a crucial role in addressing children's emotional and behavioral problems. However, the association between parental psychological resilience and emotional/beha...
Experimental and ANN-based analysis of performance, combustion, and emission characteristics of a CI engine fueled with waste plastic oil–diethyl ether–diesel blends
This study differs fundamentally from prior investigations on WPO–diesel and WPO–DEE blends by combining combustion-resolved experimentation with predictive modeling, thereby advancing WPO utilization...
GNSS/SINS/DVL integrated navigation algorithm based on adaptive differential Kalman filtering
The global navigation satellite system/strapdown inertial navigation system/doppler velocity logger (GNSS/SINS/DVL) integrated navigation system leverages the complementary advantages of its three sub...
Symptom burden, viral load, and antibody response to ancestral SARS-CoV-2 strain [D614G] in an outpatient household cohort
Background Early in the SARS-CoV-2 pandemic, description of COVID-19 illness among non-hospitalized patients was limited. Data from household cohorts can help reveal the full spect...
Visualizing vastness: Graphical methods for multiverse analysis
Multiverse analysis is an increasingly popular tool for improving the robustness and transparency of empirical research. Yet, visualization techniques for multiverse analysis are underdeveloped. We id...
Examining the impact of growth mindset and lifelong learning on teacher performance among university faculty: The mediating role of professional development
Based on social constructivist learning theory, this study constructs a structural model with teacher growth mindset and lifelong learning as independent variables, teacher professional development as...
A comparison of dynamic balance performance between non-dancers and amateur dancers across three distinct dance genres: A cross-sectional study
There is controversy regarding whether dance training improves balance performance. This study aims to compare the dynamic balance performance of non-dancers and amateur dancers, as well as to examine...
Spatiotemporal patterns of soil moisture in Shandong Province, China: An analysis using ERA5-Land datasets
Understanding the spatiotemporal variations of soil moisture (SM) is crucial for the timely identification of drought and the advancement of regional water resource management. This study utilized ERA...
Estimation of district-level fertility using age-structured census data and assessment of spatial–socioeconomic differentials in Botswana, 2022
Background Reliable subnational fertility estimates are critical for evidence-based demographic policy and planning. While Botswana’s national fertility decline is well documented,...
A biologically constrained agent-based model of cancer stem cell dynamics with reinforcement learning-guided adaptive radiotherapy
Cancer stem cells (CSCs) represent a rare but critical subpopulation within tumors, driving recurrence, resistance to therapy, and aggressive growth. To better understand CSC behavior in solid tumors,...
TGF-β1 relieves burn injury induced pain by alleviating inflammation in mouse
Burn injuries are severe traumas characterized by tissue damage and inflammation, and pain is the common symptom of burn patients. Transforming growth factor beta 1 (TGF-β1) is a multifunctional cytok...
Ursolic acid alleviates liver injury in diabetic mice induced by high-fat diet combined with streptozotocin via the NLRP3 signaling pathway
Non-alcoholic fatty liver disease (NAFLD) is a type of metabolic stress-induced liver injury that is closely related to type 2 diabetes mellitus (T2DM). Ursolic acid (UA), a natural pentacyclic triter...
Associations between canine temperament and salivary concentrations of cortisol and serotonin
Temperament influences canine behavior and helps determine a dog’s suitability as a companion or working animal. Although several temperament assessments exist, many rely on subjective evaluations, hi...
Coping mechanisms to drug stock-outs among patients seeking mental healthcare at outpatient department in Butabika National Referral Mental Hospital, Uganda: A cross-sectional study
Background Mental disorders are responsible for a significant proportion of global health burden especially in developing countries. In sub-Saharan Africa optimum care for mental h...
Determinants of return to HIV treatment after interruption on ART among HIV positive clients in Katakwi District, Uganda
Background Returning to treatment following interruptions is crucial for achieving optimal HIV care outcomes. In Uganda, despite a 20% treatment interruption rate, only 58% of clie...
Variation in food web reliance on green and brown energy pathways across ecosystem gradients
Aquatic food webs typically include highly coupled fast, ‘green’ energy pathways driven by algae or phytoplankton and slower, ‘brown’ energy channels driven by detritus and terrestrial plants. Quantif...
Exploring ideal scent detection dog characteristics for successful professional deployment as derived from face-to-face structured interviews with professional scent detection dog handlers
Scent detection dogs (SDDs) require certain behavioral characteristics for successful professional deployment. We aimed to provide insight into these characteristics by tapping into professional SDD h...
Spatiotemporal evolution of the thermal environment and influencing factors in Kashgar City’s Urban Expansion
Under the dual pressures of global warming and rapid urbanization, the mechanisms governing the evolution of high-temperature environments in arid-zone cities demand systematic analysis. This study in...
Performance evaluation and reference interval establishment of Abbott Alinity thyroid-stimulating hormone receptor antibody (TRAb) assay for diagnosing Graves’ disease
Objectives This study aims to evaluate the analytical and clinical performance of the Abbott Alinity TRAb chemiluminescent microparticle immunoassay and establish the reference int...
Feasibility and acceptability outcomes of the InMe trial - a randomised controlled trial in participants with subclinical eating and somatic symptom disorders
Dysregulations in interoception have been associated with mental health disorders including eating and somatic symptom disorders. The present study addresses the feasibility and acceptability of a nov...
MightyU – A portable sensor-based video game application for exercise training of children and adolescents with cerebral palsy
Introduction To prevent therapy fatigue and maintain motivation for daily home muscle training is important for children with cerebral palsy (CP). Therefore,...
A new molecular tool for detection of the highly invasive gecko, Hemidactylus frenatus
The Common House Gecko, Hemidactylus frenatus , also known as the Asian House Gecko (AHG), is the most significant invasive gecko globally. Detecting this speci...
Effect of stem cell therapies on tendon-bone healing after anterior cruciate ligament reconstruction in animal models: Protocol for a systematic review and meta-analysis
Introduction Anterior cruciate ligament (ACL) reconstruction is widely performed, yet insufficient tendon-bone healing remains a key contributor to graft failure. Stem cell-based i...
Visual security defense for industrial inspection based on computer vision
As intelligent manufacturing advances, computer vision-based defect detection systems have become essential components of industrial automation. However, this progress has also revealed new security v...
Caregiver-reported social impacts in down syndrome regression disorder
Background Down Syndrome Regression Disorder (DSRD) is an acute neurocognitive regression in individuals with Down syndrome (DS), causing a profound loss of acquired skills. DSRD i...