PLoS ONE
Articles in this Issue
Transcranial direct current stimulation with Bosu-ball training increases cortical activation and improves ankle-foot function among individuals with chronic ankle instability: A randomized controlled trial
Objectives This study explored the effects of High-definition transcranial direct current stimulation (HD-tDCS) with Bosu-ball training on cortical activation and ankle-foot functi...
Realizing self-sustained biomass gasification in a lab-scale downdraft reactor for compact CHP applications
Miniaturizing biomass gasifiers is key to enabling household-scale combined heat and power (CHP) systems integrated with solid oxide fuel cells (SOFCs), yet achieving self-sustained gasification at th...
Experimental investigation of tensile properties and fracture behavior of ophthalmic sutures under straight, knotted, and looped configurations: Vicryl, nylon, and polypropylene
The deformation and failure behavior of sutures play a vital role in the surgical outcomes of soft tissue encountered in ophthalmic surgeries. In the present study, the mechanical characteristics of o...
Association between pain, physical performance, and kinesiophobia in older women with low back pain: A cross-sectional study
Background Kinesiophobia is a psychological element that may contribute to persistent pain and functional decline in older women with chronic low back pain. Clarifying its role cou...
Annotation-free prediction of immunotherapy response in melanoma using single-cell transcriptomic data
Immune checkpoint inhibitors (ICIs) have transformed the advanced melanoma treatment landscape; however, a subset of patients achieve durable responses. Current biomarkers, such as PD-L1 expression an...
Rider education at Swedish riding schools: Comparing teachers' and pupils' perspectives
Previous research has highlighted a gap between scientific evidence and its application in equestrian practice, leading to concerns about horse welfare and human safety. Riding schools present an impo...
A conversational agent as a virtual therapist for patients diagnosed with schizophrenia: A preliminary study
Introduction Schizophrenia is a complex mental disorder characterized by disturbances in thinking, emotions, and behavior. Emotional dysregulation is a significant clinical issue....
A comparison of microbial community composition in two alpine springs in southern Nevada
Springs are intersections between the geosphere and hydrosphere where localized ecosystems form. Microbial communities play important roles in these aquatic ecosystems and can be identified using envi...
Predictive value of red cell distribution width to albumin ratio for acute kidney injury in patients with acute pancreatitis
Background Red blood cell volume distribution width (RDW) and albumin have been increasingly recognized for their roles in inflammatory diseases. However, the relationship between...
Anti-vibration method for sensing ring of fiber optical current transformer integrating structural design and adaptive signal processing
This paper presents an in-depth study on vibration resistance improvement and fault identification technology for fiber-optic current transformers (FOCTs). The research analyzes the working principle...
Quantifying segmentation sensitivity in OCTA: Device-specific profiles across three commercial platforms
Optical coherence tomography angiography (OCTA) enables quantitative assessment of the retinal microvasculature structure, but measurements depend on accurate layer segmentation. We quantified how sen...
Correction: PACT: A practice-driven predictive algorithm for customized transradial prosthetic socket design
Network pharmacology approach identifies novel anticancer botanicals: Experimental exploration of Falcaria vulgaris (Sickleweed) as a therapeutic candidate
Cancer remains a major global health challenge with limited therapeutic options. Medicinal plants have emerged as promising candidates for anticancer drug discovery. This study introduces an innovativ...
Design and evaluation of a prototype medical device for robotic and manual percutaneous dilatational tracheostomy
Percutaneous Dilatational Tracheostomy (PDT) is frequently performed at the intensive care unit bedside. Perioperative movements of instruments, especially inserting and removing the needle and dilato...
Research on the configurational paths for establishing high-level municipal industry-education consortiums in China: from the perspective of symbiosis theory
The municipal industry-education consortium(MIEC) is a crucial component of the development of education in China, and the provincial-level administrative regions (PARs) are committed to building high...
Evolution and structural resilience assessment of the frozen meat trade network
This study aims to reveal the spatiotemporal evolution patterns of the global frozen meat trade network from 2003 to 2023 and assess both its static and dynamic structural resilience. Based on UN comm...
Protocol for Head StART: A hybrid type II cluster randomized controlled trial evaluating community ART delivery for people newly diagnosed with HIV in refugee settlements in Uganda
Background Until recently, community-based antiretroviral therapy (ART) delivery was only available for people living with HIV on ART for ≥6 months with a suppressed viral load. Ho...
A data-driven analysis of spatiotemporal cues and experience accumulation effects for pitch type prediction
Conventional sports anticipation studies primarily rely on hypothesis-testing paradigms that target predetermined cues. However, such approaches risk overlooking unanticipated sources of predictive in...
Stability analysis of dam grouting reinforcement based on FLAC3D
Ill reservoirs have significant safety hazards, it is urgent to grout and strengthen the dangerous reservoir dams. In order to effectively evaluate the stability of the dam after grouting reinforcemen...
Fcer1g and St3gal1: Macrophage-associated angiogenesis biomarkers and therapeutic targets in sepsis-induced acute lung injury
Background Acute lung injury (ALI) involves the release of growth factors and inflammatory mediators from damaged pulmonary tissues, fostering endothelial cell proliferation, migra...
Evaluating cognitive depth of AI-generated multiple-choice questions with Bloom’s Taxonomy
Introduction While LLMs are used to generate medical and dental MCQs, their alignment with Bloom’s Taxonomy remains unexplored....
Association between hemoglobin/red blood cell distribution width ratio and acute kidney injury in sepsis and heart failure patients
Introduction The hemoglobin/red blood cell distribution width (Hb/RDW) ratio has emerged as a potential biomarker for acute kidney injury (AKI), particularly in patients with cardi...
Disposable non-enzymatic impedimetric biosensor using Mn-doped ZnS-chitosan nanocomposite for tetracycline detection
Monitoring antibiotic residues in aquaculture water is critical for food safety, environmental protection, and antimicrobial stewardship. Here, we present a proof-of-concept disposable, non-enzymatic...
Child training in the Child ViReal Support Program: Combining iVR-based cognitive training and CBT techniques in a pilot study
Introduction Attention deficits are common among school-aged children and affect their social, academic, and family lives, making it necessary to receive adequate support and inter...