PLoS ONE
Articles in this Issue
The impact of sports participation on the psychological state of the Chinese population from the perspective of sports resources
Objective Against the backdrop of the Chinese people’s growing demand for health, it is of great significance to explore the impact of sports participation on different psychologic...
Impact of the 2024 Korean medical workforce crisis on transfers in a pediatric emergency center: including comparative analyses with adults
Background In February 2024, the South Korean government announced a substantial increase in medical school admissions, leading to the sudden departure of most junior doctors. This...
Multiplex profiling of 16 immune checkpoints identifies novel serum biomarker panels for breast cancer detection and TNBC stratification: A case-control study
Background Immune checkpoints (ICs) are key regulators of anti-tumor immunity, yet their diagnostic potential as blood-based biomarkers in breast cancer (BC) remains insufficiently...
Heterogeneous biological graph convolutional network for drug-target interaction prediction
Drug–target interaction prediction plays a critical role in drug discovery by identifying potential therapeutic targets and elucidating underlying molecular mechanisms. However, existing computational...
Distributions of Xenopus species and their helminth parasites in ecological zones of Nigeria
African clawed frogs ( Xenopus species) are distributed across sub-Saharan Africa, live in water, and are hosts to diverse parasites whose distributions and hos...
Performance evaluation of a novel fully-automated molecular diagnostics system Molecision R8
Objective To evaluate the functionality of key modules of a novel fully-automated molecular diagnostics system Molecision R8 and the performance of the integrated system....
Implicit bias in safety-aligned large language models: A multi-faceted evaluation of clinical decision-making and health equity
Background Large language models are increasingly integrated into healthcare for clinical decision support and patient communication. Although these models can pass explicit social...
Exploring the relationships between eco-anxiety, eco-guilt, eco-grief, and pro-environmental behavior in the Dutch and German population: A cross-sectional study
While experiencing individual eco-emotions, such as eco-anxiety, eco-guilt, and eco-grief, has been linked to pro-environmental behavior, no prior studies have jointly investigated these variables. Re...
Introduction of artificial plants has no detrimental or beneficial effects on laboratory zebrafish husbandry but limits available swimming space
There is a broad consensus that husbandry conditions of laboratory animals need constant improvement to guarantee optimal animal welfare and research data quality. Zebrafish ( Dani...
U-shaped association between waist-to-height ratio and microalbuminuria: A cross-sectional analysis conducted within the Chinese demographic
Background While previous studies have largely overlooked the potential correlation between the waist-to-height ratio (WHtR) and microalbuminuria in Chinese adults, this study aims...
A computational text analysis of recent African digital health strategies and their attention to vulnerable populations
Background Digital health offers opportunities to transform healthcare systems and improve access to care, particularly in low- and middle-income countries. However, there is conce...
Gravity compensation for leachate grid cleaning robots in waste-to-energy plants: A modeling and simulation study
Leachate grid clogging in waste-to-energy plants severely reduces combustion efficiency by up to 42% and may cause unplanned shutdowns, leading to substantial economic losses, necessitating automated...
The impact of new urbanization on “quantity increase and quality improvement” of urban green innovation
With the rise of new urbanization (NEU) as a major national strategy, a proposition with both theoretical and practical significance has been highlighted. Whether the implementation of this strategy c...
Optimizing bike-sharing station locations: A machine learning and artificial neural networks approach using geospatial and demographic data
In the modern world, public transportation amenities are noticeably on the rise, with urban bike-sharing systems becoming well-established in many major cities. However, not all cities have these syst...
Genomic diversity of Neisseria gonorrhoeae Isolates in Kenya revealed by MLST, NG-MAST, and NG-STAR typing
Background Surveillance of Neisseria gonorrhoeae strains, their antimicrobial resistance (AMR) profiles, and tran...
Shared autonomous HERV loci transcription identifies a unique circulating CD14+-xCR1+ mononuclear cell phenotype in a patient group with post-acute sequelae of COVID-19
The human genome contains approximately 3,200 near full-length autonomous human endogenous retroviral (HERV) loci capable of transcriptional activation through long terminal repeats. In our previous s...
Dielectric and physicochemical characterization of Creole chicken breast meat for quality classification in the radiofrequency range
Understanding the quality attributes of poultry meat is essential for food safety, consumer satisfaction, and value chain efficiency. This study presents a proof-of-concept assessment of the physicoch...
Inequality measures of the generalized gamma distribution with a practicable application tool
We introduce the inequality measures of the generalized gamma distribution. The Gini coefficient, Theil, Atkinson and Pietra indexes are considered as the inequality measures. The parameters of the ge...
Assessing empathy in adults: A Malay language validation and measurement invariance of the Empathy Quotient (M-EQ)
The Empathy Quotient (EQ) is one of the most frequently used scales to measure empathy in adults and has been translated into many languages. However, there is still much debate on its dimensionality...
What outcomes are important to families with a lived experience of stillbirth? A qualitative study to inform the development of a core outcome set for stillbirth care
Objective To identify outcomes that are important to families, to inform the development of a core outcome set for stillbirth care research....
Modelling the impact of larviciding as a supplementary malaria vector control intervention in rural south-eastern Tanzania: A district-level simulation study
Combining larviciding with insecticide treated nets (ITNs) can reduce malaria transmission. However, most modelling analyses use generalized scenarios rather than incorporating local epidemiological a...
Optimization and evaluation of venturi tube reactors for non-thermal milk pasteurization using CFD method
With growing demand for preserving food’s nutritional and sensory qualities, non-thermal pasteurization methods like hydrodynamic cavitation in Venturi tubes offer an effective alternative to heat-bas...
Evolution of intraocular pressure after cataract surgery in nonglaucomatous patients: A post-hoc analysis of PERCEPOLIS clinical trial data
Purpose Intraocular pressure (IOP) drops after cataract surgery, including in nonglaucomatous eyes, but the mechanisms and factors determining this change remain unclear. Thus, pos...
Association between obesity and medical expenditures among Japanese adults treated for diabetes: A secondary analysis
In Japan, where obesity prevalence is lower than in Western countries, few studies have examined the association between obesity and medical expenditures among patients with diabetes, distinguishing b...
The impact of integrative neuromuscular training on the physical fitness of elite male martial arts Sanda Athletes
Objective Integrative Neuromuscular Training (INT) is recognized not only for its potential in preventing sports injuries but also for enhancing athletic performance. Understanding...