PLoS ONE
Articles in this Issue
Virological investigation and comparative genomic analysis of elephant endotheliotropic herpesvirus 1B infection in an Australian captive herd of Asian elephants (Elephas maximus)
Elephant endotheliotropic herpesviruses (EEHV) pose a significant threat to the conservation of Asian elephants ( Elephas maximus ) worldwide, with a high morta...
Retraction: Determinants of correct knowledge on tuberculosis transmission and self-reported tuberculosis prevalence among general population aged 15–49 years in Myanmar
Temporal transcriptomic profiling of pulmonary thromboembolism reveals persistent NETosis- and ferroptosis-associated gene signatures and enhanced thrombolysis with adjunctive DNase I
Objective To investigate the dynamic pathophysiology of pulmonary thromboembolism (PTE), focusing on the roles of neutrophil extracellular traps (NETs) and ferroptosis, and to eval...
Drivers of sustainable practices in a developing country’s garment and textile industry: The role of sustainability challenges, limited material access, and economic constraints
Sustainable practices in small and medium-sized enterprises (SMEs) are critical for environmental resilience and economic viability, particularly in developing economies like Ghana’s garment and texti...
Work-life realities of doctors in Georgia and their impact on mental health and work-related well-being: A cross-sectional study
Background Physicians worldwide are exposed to high occupational demands, long working hours, and emotional strain, placing them at increased risk for stress, depressive symptoms,...
Predicting severe COVID-19 disease in adults: A single-centre cohort study during the first three pandemic waves in 2020–2021 in Vilnius, Lithuania
Background Since its emergence, the COVID-19 infection has led to significant morbidity and mortality worldwide. Early identification of patients at risk for severe disease is esse...
Determinants of knowledge and attitudes toward Mpox among medical students: A cross-sectional study from Kurdistan region of Iraq
Introduction and Objectives Mpox is a re-emerging zoonotic viral infection that has recently caused widespread outbreaks in previously non-endemic regions, becoming an internationa...
Comprehensive multi-omics analysis reveals prognostic, immune, and therapeutic signatures of TNFAIP family genes in breast cancer
Background Tumor necrosis factor-alpha-induced proteins (TNFAIPs) are key regulators of inflammation, apoptosis, and immune signaling, yet their integrated roles in breast cancer (...
Probiotics, synbiotics and berberine in Type 2 diabetes mellitus: A systematic review, meta-analysis, and molecular dynamics simulation study
Background Type 2 diabetes mellitus is characterized by impaired regulation of blood glucose. Probiotics, synbiotics, and berberine (BBR) have been proposed as adjunctive intervent...
Towards intelligent railway monitoring: A novel hybrid deep learning architecture for railway obstacle detection
Railways are among the most efficient modes of transportation, capable of moving large quantities of goods and passengers over long distances at relatively low cost. However, accidents frequently occu...
Adapting a medication adherence app for adolescents and young adults in Makurdi, Benue State: The Lu Dedoo Project
Introduction Adolescents and young adults living with HIV (AYALHIV) face persistent challenges with antiretroviral therapy (ART) adherence, a key determinant...
Body mass index change trajectories and gastric cancer risk: Effect modification by sex, age, smoking, and menopausal status in Korean adults aged ≥40 years
This study examined the association between body mass index (BMI) and gastric cancer risk and specifically evaluated effect modification by sex, age, smoking, and menopausal status. A nationwide cohor...
Survival disparities and competing mortality risks in offspring of consanguineous marriages in Yemen: A 26-year retrospective cohort analysis
Background Consanguineous marriage is prevalent in many global populations and increases the risk of autosomal recessive genetic disorders in offspring. However, long-term disorder...
GSEA and the coexpression network approach identify novel pathway connections of molecular processes affected in Porto-sinusoidal vascular disease
Background Porto-sinusoidal vascular disease (PSVD) is a complex, rare liver disease characterized by the absence of cirrhosis, with or without the presence of portal hypertension...
Correction: Cohort profile: The Bristol IVF Study- A longitudinal study of women, their partners and treatment outcomes following assisted reproductive technologies
The effect of moderate physical activity on NK cells populations and cytotoxic T lymphocytes in young, healthy women
Background Physical activity is a modifiable lifestyle factor known to reduce the risk of many diseases, including cancer, partly through improvement of immune function. Physical e...
Predictors of binge drinking among adults in Autonomous Province of Vojvodina, Serbia: Data from the population-based behavioral risk-factors surveillance system
Introduction Alcohol use has been linked to harmful health outcomes. In this study, we examined the association between binge drinking and sociodemographic characteristics as well...
Role for plant foods in kidney health among middle-aged individuals environmentally exposed to cadmium and lead
Plant food consumption has been associated with potential kidney health benefits; however, in polluted environments, such benefits may be diminished by exposure to toxic metals, notably, cadmium (Cd)...
Risk factors for post-induction hypotension in patients with end-stage renal disease undergoing general anesthesia
Background Patients with end-stage renal disease (ESRD) are at highly susceptible to hemodynamic instability during anesthesia induction. However, data specific to this population...
Phage-plasmid-like elements are found throughout diverse environments and encode niche-specific functional traits
Phage-plasmids are unique mobile genetic elements that function as plasmids and temperate phages. While it has been observed that such elements often encode antibiotic resistance genes and defense sys...
Effects of muscle-tendon mechanical properties and electromyographic activity patterns on individual differences in force-power relationship
This study aimed to examine the effects of muscle-tendon mechanical properties and electromyographic activity patterns on individual differences in the force-power relationship during jumping with and...
Three-dimensional shape cues affect human and artificial recognition systems differently
Humans and neural networks use shape and texture information differently. While humans weigh shape heavily in their ultimate classification decision, neural networks are more biased towards texture cu...
Multi-objective location-routing optimization of first-mile pre-cooling distribution center networks in the agricultural cold chain
China is both a major producer and consumer of fresh agricultural products, making cold chain logistics essential for preserving quality and reducing post-harvest loss. However, insufficient pre-cooli...
Key functions for the transferability of a French school-based health promotion intervention
The “ Alliance for Health ” intervention is a French evidence-based initiative targeting teachers and after-school care staff, aimed at supporting the developme...
The influence of job content and autonomy on psychological well-being through work identity and job crafting among pharmacists in Pakistan
Background Psychological well-being of pharmacists is necessary for safe and effective healthcare delivery, particularly in high-stress environments. The present study was aimed to...