PLoS ONE
Articles in this Issue
Hybrid 1D CNN-BiLSTM with focal loss for robust intrusion detection in in-vehicle CAN networks
The Controller Area Network (CAN) bus serves as the primary communication framework in modern vehicles, enabling reliable data exchange among Electronic Control Units (ECUs) for seamless interaction....
Rates and predictors of hospital visits after “Possible AF” alerts from a home ECG monitor in older adults with hypertension: A sub-analysis of the Omron Heart Study
Background Home ECG can detect atrial fibrillation (AF), but patients’ hospital visit behavior after “possible AF” alerts remains uncertain. We assessed the rates, timing, and corr...
Design and testing of a soil-dividing device for a pineapple strip-tillage furrower
To address issues such as high soil backfilling rates and difficulty in maintaining the trench shape during the operation of pineapple strip-rotary cultivators, we designed a V-shaped soil-dividing de...
Enhancing low-light images with MSHCDI-Net: A multi-scale hybrid cross-domain interaction approach
Low-light image enhancement aims to improve visual visibility and perceptual quality under challenging illumination conditions. However, conventional convolutional neural networks (CNNs) are inherentl...
YOLO11-FR: A bridge crack detection method based on frequency-domain fusion and an edge enhancement mechanism
Bridge cracks are important indicators of structural deterioration, and accurate crack detection is essential for bridge operation, maintenance, and safety assessment. However, crack detection remains...
Navigating resilience: Mental health self-care among middle-aged and older LGBTQ+ adults in Thailand
Introduction This study explores how middle-aged and older LGBTQ+ adults in Thailand engage in mental health self-care within complex social and cultural environments. While global...
Skin manifestations of primary COVID-19 infection with the omicron variant
Background Although cutaneous manifestations of COVID-19 have been increasingly documented across earlier variants, the dermatological characteristics specifically associated with...
Correction: Modelling Hepatitis B virus related hospital discharges in Spain: ARIMAX based liver disease forecasting tool for hospital workload and mortality progression
Adverse fetal/neonatal and obstetric outcomes in pregnant women with heart disease: Data from the Registry of Pregnancy and Cardiac Disease (ROPAC) of the Kermanshah, Iran
Background Pregnancy complicated by heart disease can pose serious risks and complications for both the mother and the fetus. Understanding the prevalence of these conditions durin...
Applying Brazilian front-of-pack nutrition labeling and PAHO nutritional criteria to digital food advertising: regulatory implications for protecting children and adolescents
Front-of-pack nutrition labeling (FoPNL) and restrictions on food advertising are regulatory strategies to support informed dietary choices and reduce exposure to unhealthy food. These measures are of...
Sensemaking at work: How rationalized knowledge hiding and communication patterns affect decision quality
This paper employs sensemaking theory to examine the relationships between rationalized knowledge hiding, communication patterns, and the quality of decision-making in information technology firms. Ad...
Herpesvirus reactivation is associated with mortality in critically ill ICU patients with COVID-19: Insights from a retrospective single-center analysis of 455 cases
Background Critically ill patients with COVID-19 frequently develop viral reactivation, yet the clinical significance of herpes simplex virus type 1 (HSV-1) and cytomegalovirus (CM...
Teaching persuasive essay writing online to first-year undergraduates: A phenomenological study of instructional design and learning experiences
The teaching and learning of academic essays faced difficulties in in-person classes. Challenges in academic essay instruction were exacerbated in online learning environments during COVID-19. Yet som...
Chemsex among men who have sex with men (MSM) in Yangon, Myanmar: Prevalence, practices, and associated risk factors
Introduction Chemsex is the intentional use of psychoactive substances to facilitate, enhance, or prolong sexual encounters. It is notably common among men who have sex with men (M...
New integrative methodology for the excavation and study of mass graves and partially commingled remains
The resolution of commingled human skeletal remains is a phenomenon increasingly encountered by archaeologists and anthropologists. Its difficulty is due to the complexity of the task itself, but also...
First-generation medical school applicants: A quantitative study designed to identify areas of educational support
First-generation (First Gen) students are unique medical school applicants. Due to their lived experience, they approach patient care by prioritizing trust, comfort and understanding. They have proven...
TBX20 promotes doxorubicin resistance in breast cancer cells through enhanced ABCC1 expression and inhibition of mitophagy
This study aimed to investigate the role and mechanism of T-box transcription factor 20 (TBX20) in doxorubicin resistance in breast cancer cells. RNA-seq data from breast cancer samples in the TCGA da...
Easy conic intersection with the common self-polar triangle
Intersecting two conics is a classical problem that is frequently encountered in many different areas of science, engineering, and art. For example, under perspective projection (e.g., in camera image...
Sequential administration of sclerostin antibody and parathyroid hormone differentially modulates fracture healing in a murine tibial osteotomy model
Anabolic agents such as parathyroid hormone (PTH) analogs and sclerostin antibody (Scl-Ab) enhance fracture healing through distinct mechanisms, but whether the order of administration affects healing...
A phase III double-blind, placebo-controlled, randomized withdrawal trial of 5‑aminolevulinic acid hydrochloride with sodium ferrous citrate for efficacy and safety in patients diagnosed as Leigh syndrome
Objective A phase III, double-blind, placebo-controlled, randomized withdrawal trial of SPP‑004 (5‑aminolevulinic acid hydrochloride and sodium ferrous citrate) was conducted to co...
Enhancing medical intern competence in urethral catheterization: Impact of simulation-based training on knowledge, self-efficacy, and clinical outcomes
Introduction Urethral catheterization is a common procedure, yet most related complications occur when performed by new medical interns. Studies have shown inadequate training and...
The pharmacist’s role in the periprocedural management of anticoagulation in Canada: A qualitative study protocol
Anticoagulants are crucial for both the immediate and ongoing management of thromboembolic disorders, including atrial fibrillation and venous thromboembolism, and for patients with mechanical heart v...
Energy localization and spatiotemporal pattern evolution mechanism of spatial thin-film structures under parametric excitation
This paper investigates energy localization and spatiotemporal pattern evolution in spatial thin-film structures subjected to parametric excitation. A nonlinear thin-shell model is established by comb...
Physical measures of physical functioning as prognostic factors in predicting outcomes for neck pain: Protocol for a prospective longitudinal cohort study
Introduction Neck pain is a common musculoskeletal condition that contributes to significant global burden. Evidence on physical measures of functioning as prognostic factors for n...
Incidence and risk factors of postoperative delirium in children with congenital heart disease
Background Postoperative delirium (POD) is an important neurocognitive complication following congenital heart disease (CHD) surgery in pediatric patients. While recognized for its...