PLoS ONE
Articles in this Issue
Bayesian spatio-temporal disease mapping of COVID-19 cases in Bangladesh
Background COVID-19 is a highly transmittable respiratory illness induced by SARS-CoV-2, a novel coronavirus. The spatio-temporal analysis considers interactions between space and time is essential f...
Impact of overwork on self-assessed health of rural-to-urban migrants: Limitations of work incentives moderation effect and industry heterogeneity
Overwork is widely recognized as harmful to workers’ physical and mental health, yet studies focusing on income-driven rural-to-urban migrants are lacking. This research aims to explore the effects of...
NPR1-like genes in Theobroma cacao: Evolutionary insights and potential in enhancing resistance to Phytophthora megakarya
Nonexpressor of pathogenesis-related 1 (NPR1) is crucial for activating the plant immune system through the signaling molecule salicylic acid (SA), which triggers systemic acquired resistance (SAR) in...
Photogrammetric approach to detect road pavement friction
This paper deals with evaluation of photogrammetric measurements of pavement macrotexture for the purposes of new non-contact method for determination of pavement skid resistance. The aim was to creat...
Effects of initial foot position on neuromuscular and biomechanical control during the stand-to-sit movement: Implications for rehabilitation strategies
Background Initial foot position (IFP) is one of the important movement strategies that influence neuromuscular and biomechanical control during sit-to-stand (STS) movements. Similarly, stand-to-sit (...
Disease trajectory and competing risks of patients with cirrhosis in the US
Background Cirrhosis is a dynamic disease process leading to liver-related death, which has increased by over 65% over the last decade. Unpredictable hepatic decompensation complications are a major s...
Mixed attention ensemble for esophageal motility disorders classification
Esophageal motility disorders result from dysfunction of the lower esophageal sphincter and abnormalities in esophageal peristalsis, often presenting symptoms such as dysphagia, chest pain, or heartbu...
Efficacy of Ginkgo biloba on parameters in glaucoma: A systematic review
Purpose This study aims to analyse the efficacy of GBE administration in patients with glaucoma and healthy volunteers. Methods This systematic review was performed according to the PRISMA 2020 guid...
Semi-rational evolution of a recombinant DNA polymerase for modified nucleotide incorporation efficiency
Engineering improved B-family DNA polymerases to catalyze 3′-O-modified nucleotide reversible terminators is limited by an insufficient understanding of the structural determinants that define polymer...
Adult male-specific inverse association between dry eye disease and intraocular pressure: KNHANES 2010–2012
Purpose To investigate the association between dry eye disease (DED) and intraocular pressure (IOP) in the general adult population of South Korea. Methods We enrolled 13,194 adults (age ≥19 years)...
Association between anthropometric indices and chronic kidney disease: Insights from NHANES 2009–2018
Introduction The strong association between obesity and chronic kidney disease (CKD) has been empirically validated, yet traditional measures like the Body Mass Index (BMI) fail to accurately assess t...
Hybrid-RViT: Hybridizing ResNet-50 and Vision Transformer for Enhanced Alzheimer’s disease detection
Alzheimer’s disease (AD) is a leading cause of disability worldwide. Early detection is critical for preventing progression and formulating effective treatment plans. This study aims to develop a nove...
Cultivating key disciplinary competencies among university students against the background of China’s new engineering education initiative
The development of students’ core disciplinary competencies is crucial to the quality of talent cultivation against the background of China’s New Engineering Education initiative. We condensed a liter...
Barriers to participation in Iran’s Integrated Geriatric Care Program: A qualitative study
Background A significant number of older adults still have unfulfilled needs related to healthcare and social services. Policymakers and health administrators can turn this challenge into a golden opp...
Cloning and bioinformatics analysis of key gene ShOMT3 of podophyllotoxin biosynthesis pathway in Sinopodophyllum hexandrum
Sinopodophyllum hexandrum (S. hexandrum) is an endangered traditional Chinese medicine as abundant podophyllotoxin with powerful anticancer activity. In this study, the rootstalks of S. hexandrum from...
Study on lean production management of new energy vehicle body painting based on the dual perspectives of digital transformation and VSM
The automobile body painting production system exists in the backward management concept of focusing on production and ignoring environmental protection, focusing on traditional technology and unwilli...
Evaluating elexacaftor/tezacaftor/ivacaftor (ETI; Trikafta™) for treatment of patients with non-cystic fibrosis bronchiectasis (NCFBE): A clinical study protocol
Background Non-cystic fibrosis bronchiectasis (NCFBE) is a disease that exhibits dilatation of airways, airflow obstruction, persistent cough, excessive sputum production, and refractory respiratory i...
A predictive model to assess the risk of developing hyperlipidemia in patients with type 2 diabetes
Background Type 2 diabetes (T2D) is increasingly recognized as a significant global health challenge, with a rising prevalence of hyperlipidemia among diabetic patients. Effectively predicting and red...
Risk and outcomes of healthcare-associated infections in three hospitals in Bobo Dioulasso, Burkina Faso, 2022: A longitudinal study
Background Healthcare-associated infections (HAIs) are one of the most common adverse events in healthcare and represent a major public health problem. The present study was conduc...
Research on the aesthetic sensitivity evaluation of tourism mascots based on semantic differential method
In order to better meet the emotional needs of consumers and enhance the design of mascots that integrate multicultural elements, this study uses sensory engineering theory to explore the correlation...
Academic writing challenges and supports for early-stage Chinese postgraduates: A mixed-methods study on teaching-research integration, supervisor engagement, and self-efficacy
Enhancing academic publication outcomes and writing skills in postgraduates is a key goal for higher education institutions, ideally through early intervention. This study examines the challenges and...
Anxiety among pregnant women in Addis Ababa, Ethiopia
Background Anxiety is one of the most prevalent mental health problems during pregnancy which result in various maternal and newborn complications affecting the health and well-being of the mother and...
RETRACTED: Fast fault diagnosis of smart grid equipment based on deep neural network model based on knowledge graph
The smart grid is on the basis of physical grid, introducing all kinds of advanced communications technology and form a new type of power grid. It can not only meet the demand of users and realize the...
Hydrothermal treatment of yeast cell wall generates potent anti-proliferative agents targeting MCF7 breast cancer cells effectively even under culture conditions separated by a plastic wall
Traditionally, the yeast cell wall (YCW) has limited applications because of its low solubility. To overcome this, a novel method was developed using a hydrothermal reaction to enhance its solubility...
Optimal dose and duration of iron supplementation for treating iron deficiency anaemia in children and adolescents: A systematic review and meta-analysis
Introduction Iron deficiency anaemia (IDA) accounts for nearly two-thirds of all anaemia cases globally. Despite the widespread use of iron supplementation, the optimal dose and duration for treating...