PLoS ONE
Articles in this Issue
Prognosis of extracolonic findings on clinical computed tomographic colonography: A single-center experience
Computed tomographic colonography (CTC) is crucial for colorectal cancer screening and secondary examinations, often revealing extracolonic findings with unclear significance. This study retrospective...
Barriers to and facilitators of rehabilitation according to socio-economic status, after acute respiratory distress syndrome due to COVID-19: A qualitative study in the RECOVIDS cohort
Background The COVID-19 pandemic may have compounded social disparities in access to healthcare, with possible deleterious consequences on the functional prognosis of patients after a stay in the inte...
Needs, rationale, and outcomes of leadership education in neurosurgery
Background Surgeons are expected to lead teams/organizations to achieve optimal patient outcomes; however, few receive formal education in leadership. The goals of the study were to: 1) assess the un...
Incidence and factors associated with SARS-CoV-2 infection and re-infection among people experiencing homelessness in Toronto, Canada: A prospective cohort study
People experiencing homelessness are at elevated risk of SARS-CoV-2 infection, yet estimates generally exclude re-infections and rely on data sources affected by testing policies or study timing. In t...
Nanoencapsulation of amitriptyline enhances the potency of antidepressant-like effects and exhibits anxiolytic-like effects in Wistar rats
Depression poses a significant global health challenge, affecting an estimated 300 million people worldwide. While amitriptyline (Ami) remains one of the most effective antidepressants, its numerous s...
Impact of COVID-19 on In-Patient and Out-Patient services in Bangladesh
Introduction The global Coronavirus disease (COVID-19) pandemic disrupted healthcare systems, reducing access to medical services. In Bangladesh, strict lockdowns, healthcare worker shortages, and res...
Effects of cochlear implantation on gait performance in adults with hearing impairment: A systematic review
Background Previous systematic reviews evaluated the effect of hearing interventions on static and dynamic stability and found several positive effects of hearing interventions. Despite numerous revie...
A two-factor scale of perceived power
Power-the capacity to influence outcomes-manifests in two distinct forms: social power, defined as the perceived ability to control others’ behaviors and decisions, and personal power, characterized b...
Ethiopian antimicrobial consumption trends in human health sector: A surveillance report 2020–2022
Background Antimicrobial resistance (AMR) poses a severe global health threat, driven by the overuse and misuse of antimicrobials across the human, agricultural, and veterinary sectors. To combat thi...
Molecular screening and dynamics simulation reveal potential phytocompounds in Swertia chirayita targeting the UspA1 protein of Moraxella catarrhalis for COPD therapy
Chronic obstructive pulmonary disease (COPD) is a global health burden, with Moraxella catarrhalis significantly contributing to acute exacerbations and increased healthcare challenges. This study aim...
Factors influencing disaster preparedness behaviors of older adults
This study examines the heterogeneity in disaster preparedness behaviors among older adults and the factors that influence them, with the aim of offering policy recommendations to mitigate casualties...
Exploring the narrative landscape: The discursive construction of identity for Chinese enterprises in Africa
This study investigates the construction of corporate identities by Chinese enterprises in Africa, employing the Three-dimensional Model of Fairchough in conjunction with the corporate communication s...
Why are critical event checklists not always used in the perioperative setting?: A retrospective survey
Introduction During surgery and anesthesia, life-threatening critical events, including cardiac arrest, may occur. By facilitating recall of key management steps, suggesting diagnostic possibilities,...
Restoration of angiogenic capacity in senescent endothelial cells by a pharmacological reprogramming approach
Senescent endothelial cells (EC) are key players in the pathophysiology of cardiovascular diseases and are characterized by a reduced angiogenic and regenerative potential. Therefore, targeting these...
Contribution of health system governance in delivering primary health care services for universal health coverage: A scoping review
Background The implementation of the primary health care (PHC) approach requires essential health system inputs, including structures, policies, programs, organization, and governance. Effective healt...
Development and application of a binary medium bond contact model for calcareous sands
In the construction process of islands and reefs in the South China Sea, calcareous sand, as an important foundation and building material, has been widely used in engineering practice. It is crucial...
How can a top-down government program can be sustainable: A case study of horticulture village program in South Sulawesi Province
The horticulture village program is one of the activities in increasing sustainable vegetable production. The activity was carried out in 2021 and one of the provinces that carried it out was the prov...
A tale of be(com)ing a Sport Nutritionist: Reflexive insights from a researcher-practitioner entering the field
Qualitative research can facilitate an understanding of the richness and complexity of human experience, shedding light on multifaceted relationships that exist within sporting environments. Within th...
Enhancing nutritional value and quality of cookies through pumpkin peel and seed powder fortification
Background Recently, the pumpkin by-products such as peels and seeds become more and more interesting for confectionary sector, because of the nutritional and bioactive composition. The study was cond...
Expression of Concern: Peptides of presenilin-1 bind the amyloid precursor protein ectodomain and offer a novel and specific therapeutic approach to reduce β-amyloid in Alzheimer’s disease
Predominance of extensively-drug resistant Acinetobacter baumannii carrying bla OXA-23 in Jordanian patients admitted to the intensive care units
Background and Aim The global emergence of Acinetobacter baumannii is of great concern, especially inside intensive care units (ICUs). This study investigated the prevalence, antibiotic resistance, bi...
The effects of restraint stress and orthodontic tooth movements on the intestinal epithelial structure and metabolic function in rats
Chronic stress and orthodontic treatment have been revealed to trigger systemic stress responses in rats. This study aimed to investigate the effects of restraint stress and orthodontic treatment on t...
Incidence of macular hole in patients undergoing pars plana vitrectomy for submacular hemorrhage
Purpose To investigate the incidence of macular hole (MH) during pars plana vitrectomy (PPV) for submacular hemorrhage (SMH) due to either retinal arterial macroaneurysm (RAM) rupture or age-related m...
The effects of plyometric training with speed and weight overloads on volleyball players’ strength, power, and jumping performance
Background The principle of gradual overload is crucial in improving sports performance, yet the effects of combining speed and weight overloads in plyometric training remain understudied. Objective...
Risk factors for osteoporosis in elderly patients with type 2 diabetes: A protocol for systematic review and meta-analysis
Background Osteoporosis is a prevalent chronic result of diabetes. Osteoporosis susceptibility is raised by unstable blood glucose levels, oxidative stress, hormonal abnormalities, and other factors....