PLoS ONE
Articles in this Issue
Severe adverse reactions to benzathine penicillin G in rheumatic heart disease: A systematic review and meta-analysis
Background Fear of severe adverse reaction (SAR) and reluctance of health care providers to administer intramuscular injections are major contributing factors to poor adherence of benzathine penicilli...
Analysis and study of risk factors related to the progression of non-alcoholic fatty liver disease: A retrospective cohort study
Objective Non-alcoholic fatty liver disease (NAFLD) is becoming increasingly prevalent worldwide. This study aimed to analyze the risk factors associated with NAFLD progression by collecting and evalu...
What works, how and in which contexts when using digital health to support parents/carers to implement intensive speech and language therapy at home for children with speech sound disorder? A realist review
Purpose Digital health solutions to support parent-implemented interventions alongside direct speech and language therapist (SLT) input could help increase intervention intensity for children with spe...
OA-HybridCNN (OHC): An advanced deep learning fusion model for enhanced diagnostic accuracy in knee osteoarthritis imaging
Knee osteoarthritis (KOA) is a leading cause of disability globally. Early and accurate diagnosis is paramount in preventing its progression and improving patients’ quality of life. However, the incon...
The association between the triglyceride-glucose index with all-cause and cardiovascular mortality within the infertility population
Background The relationship between triglyceride-glucose (TyG) index and all-cause or cardiovascular mortality among infertile women remains unclear. In this study, we intended to utilize a national c...
Identification and validation of diagnostic markers and drugs for pediatric bronchopulmonary dysplasia based on integrating bioinformatics and molecular docking analysis
Background BPD is a prevalent chronic lung disease in infancy with lifelong impacts. Its early diagnosis and treatment are hindered by complex pathophysiology and limited mechanistic understanding. Th...
Genetic and ecological characterization of the giant reed (Arundo donax) in Central Mexico
Arundo donax (giant reed) is currently found in all tropical-subtropical and warm-temperate areas of the world. In Mexico, A. donax is a common introduced species, growing in a variety of climates and...
Retraction: An analysis of machine learning risk factors and risk parity portfolio optimization
Sentiment mining of online comments of sports venues: Consumer satisfaction and its influencing factors
In the context of consumer economics, it is imperative to consider the functionality of sports venues based on customer demand. However, traditional survey methods are time-consuming, resource-intensi...
Effects of underground coal mining disturbance on bacterial community diversity and its assembly processes
Vegetation restoration is an important indicator for evaluating the health of mining ecosystems. Soil microorganisms influence soil material cycling and play an important role in vegetation restoratio...
Assessing the efficacy and safety of different nonsteroidal anti-inflammatory drugs in the treatment of osteoarthritis: A systematic review and network meta-analysis based on RCT trials
Introduction Osteoarthritis (OA) as a degenerative disease, has seen a continuous rise in incidence and prevalence globally since 1990, imposing a significant disease burden. NSAIDs (Nonsteroidal anti...
Appraisal of groundwater conditions through hydrogeophysical and hydrogeological approach in Cholistan area, district Bahawalpur, Punjab, Pakistan
The sustainable groundwater supply has a prime importance for the development of an area. Unfortunately, the groundwater-related issues are heading towards terrible situation regionally and locally as...
The impact of suicide prevention training for nursing assistant students: Knowledge and willingness to intervene
Nursing assistants frequently encounter individuals at risk of suicidal behavior in various healthcare settings. This study aims to assess the impact of suicide prevention training materials on nursin...
“I would have said ‘bad news’ but now I say ‘different news”: Mixed methods evaluation of a communication skills training for healthcare professionals in the first 1000 days of life
Background Receiving a diagnosis of congenital anomalies in the first 1000 days of life can have significant implications for a family’s emotional and mental wellbeing. We refer to this as different n...
Comparative analysis of diagnostic performance in mammography: A reader study on the impact of AI assistance
Purpose This study evaluates the impact of artificial intelligence (AI) assistance on the diagnostic performance of radiologists with varying levels of experience in interpreting mammograms in a Malay...
Variable selection in mixture cure models using elastic net penalty: application to COVID-19 data
In survival analysis, it is often assumed that all individuals will eventually experience the event of interest if followed long enough. However, in many real-world scenarios, a subset of individuals...
Comparing visual outcomes of nAMD treatment during and after the COVID-19 restrictions period
Main objective Compare treatment outcomes of newly diagnosed neovascular age-related macular degeneration (nAMD) during and after the COVID-19 restrictions. Methods This retrospective study at the R...
Gene expression-based identification of prognostic markers in lung adenocarcinoma
Introduction Many studies have aimed at identifying additional prognostic tools to guide treatment choices and patient surveillance in lung cancer by assessing the expression of individual proteins th...
Retraction: Dynamic nonlinear CO2 emission effects of urbanization routes in the eight most populous countries
Use of virtual reality in the reduction of pain after the administration of vaccines among children in primary care centers in Central Catalonia: Randomized clinical trial
Background Pain and anxiety caused by vaccination and other medical procedures in childhood can generate discomfort in both the patient and their parents. Virtual reality is a non-pharmacological dist...
Quality assessment of medicinal material Daqingye and Banlangen from Isatis tinctoria Fort. reveals widespread substitution with Strobilanthes species
Background Isatidis Folium (Daqingye, DQY) and Isatidis Radix (Banlangen, BLG) are the leaf and root of the plant Isatis tinctoria Fort. (syn. Isatis indigotica Fort.), commonly prescribed for detoxif...
Predictive analysis of seismic damage to buildings near-surface faults under the influence of multiple factors
The investigation and analysis of building damage is the most direct and effective method to reveal its mechanism, but the statistics and analysis of building damage sample data near surface faults ar...
No acceleration of recovery from exercise-induced muscle damage after cold or hot water immersion in women: A randomised controlled trial
This study compared the effects of cold water immersion (CWI) and hot water immersion (HWI) on muscle recovery following a muscle-damaging exercise protocol in women. Thirty healthy women (23.3 ± 2.9...
Unveiling the mechanism of dodecylphosphorylcholine as an extremely promising drug delivery system: From self-assembly clusters to drug encapsulation pathways
Significant progress has been achieved in cancer treatment with Doxorubicin (DOX), yet its low toxicity and poor bioavailability have long troubled scientists. Dodecylphosphorylcholine (DPC), as a can...
Development of a multidimensional prediction model for long-term prognostic risk in patients with acute coronary syndromes after percutaneous coronary intervention: A retrospective observational cohort study
Background The aim of this study is to examine the critical variables that impact the long-term prognosis of patients with acute coronary syndrome (ACS) after percutaneous coronary intervention (PCI)...