PLoS ONE
Articles in this Issue
From hashtags to ballots: Conceptualizing political influencers and evaluating their impact on election outcomes
Social media influencers have evolved beyond lifestyle content, with a new subset - political influencers - rising to prominence in shaping political discourse. This paper seeks to highlight important...
A systematic analysis for disease burden, risk factors, and trend projection of Alzheimer’s disease and other dementias in China and globally
Background This study aims to provide improvement directions for aging societies by analyzing the disease burden, risk factors and trend forecasts of AD and other dementias (ADD) in China and globally...
Forecasting second-hand house prices in China using the GA-PSO-BP neural network model
While the traditional genetic algorithms are capable of forecasting house prices, they often suffer from premature convergence, which adversely affects the reliability of the forecasts. To address thi...
Association of albumin-bilirubin grade with survival outcomes in patients with cholangiocarcinoma
Background Numerous studies have reported the association between preoperative albumin-bilirubin (ALBI) grade and survival outcomes in patients with cholangiocarcinoma (CCA). However, the results are...
CLEFT-Q SwePsych protocol: A prospective observational study to investigate the psychometric characteristics test-retest reliability, responsiveness, and interpretability of CLEFT-Q
Objectives Patient perceived benefit of treatment for cleft lip and/or palate is of great importance since it is central to development of cleft care. CLEFT-Q is a cleft-specific questionnaire on heal...
Promiscuous structural cross-compatibilities between major shell components of Klebsiella pneumoniae bacterial microcompartments
Bacterial microcompartments (BMC) are submicrometric reactors that encapsulate dedicated metabolic activities. BMC-H hexamers, the most abundant components of BMC shells, play major roles for shell pl...
Diabetes service decentralization to primary healthcare unit in Tigray, Ethiopia: A pilot study
Background The prevalence of diabetes mellitus has been increasing in the past few decades. Mortality and morbidity have increased faster in low- and middle-income countries than in high-income countr...
Retraction: Applications of bioconvection for tiny particles due to two concentric cylinders when role of Lorentz force is significant
Plasma-based proteomics analysis of molecular pathways in canine diabetes mellitus after astaxanthin supplementation
The hyperglycemic state in diabetes mellitus induces oxidative stress and inflammation, contributing to diabetic tissue damage and associated complications. Astaxanthin, a potent antioxidant carotenoi...
Performance evaluation of machine learning techniques in surface morphology and corrosion prediction for A286 3D printed micro-lattice structures
The development of lightweight, corrosion-resistant metallic lattice structures has gained significant attention in aerospace, defense, and structural applications, where material durability and weigh...
Soft and hard tissue changes after compensatory treatment in skeletal class III malocclusion
Background The camouflage treatment of skeletal class III malocclusion can include both premolar extraction and mandibular third molar extraction-based approaches. This study aimed to compare an all f...
The individual and sequential effect of focused attention and open monitoring meditation on mindfulness skills
Mindfulness meditation has two components: focused attention (FA) meditation and open-monitoring (OM) meditation. Based on traditional Buddhist principles, it is recommended that FA meditation be prac...
Development and characterization of a 2D porcine colonic organoid model for studying intestinal physiology and barrier function
The porcine colon epithelium plays a crucial role in nutrient absorption, ion transport, and barrier function. However ethical concerns necessitate the development of alternatives to animal models for...
Climate: The dominant factor influencing the spatial distribution pattern of the leaf trait network of Populus euphratica along the main stream of the Tarim River
Leaves are the primary interface through which plants interact with the environment, their functional traits (morphology, anatomy, physiology) directly reflecting ecological strategies that mediate sp...
Zoom in on learning with a virtual microscope: A convergent parallel mixed-method study
Knowledge of histology is essential for many disciplines in professional health education. Virtual Microscopes (VMs) are increasingly becoming popular as a cost-effective teaching tool for histology....
Fracture damage and energy dissipation of granite based on continuous-discontinuous coupling
A three-dimensional continuous-discontinuous numerical model was established through FLAC3D-PFC3D simulation coupling to study the fracture damage and energy dissipation characteristics of granite und...
A protocol for the HEaring Impairment Data Infrastructure (HEIDI) study
Background Research suggests that early detection of hearing loss, coupled with prompt and appropriate treatment, can significantly alleviate its negative impacts. Routinely collected real-world data,...
Cohabitation in sub-Saharan Africa: Does women empowerment matter? Insights from the demographic and health survey
Background Cohabitation is increasingly challenging traditional family structures in sub-Saharan Africa (SSA), marking a significant cultural shift in the region. This rise in non-traditional unions p...
Uncovering bridging diseases in complex multimorbidity pathways: A network science approach
Multimorbidity, the co-occurrence of multiple chronic diseases, represents a significant challenge in healthcare, necessitating advanced analytical methods for a better understanding. Although numerou...
Passive vs. active warm-up combined with stretching on hamstring flexibility and maximal voluntary contractions
This study aimed to compare the effects of passive and active warm-up protocols combined with static or neurodynamic stretching on hamstring muscle function. Sixteen individuals (7 men and 9 women) pe...
A KAN-based hybrid deep neural networks for accurate identification of transcription factor binding sites
Background Predicting protein-DNA binding sites in vivo is a challenging but urgent task in many fields such as drug design and development. Most promoters contain many transcription factor (TF) bindi...
1H-MRS study of hippocampus in advanced prostate cancer patients: Relationship between hippocampal secondary damage and cognitive disorder following combined androgen blockade therapy
Objectives To determine whether 6 months of combined androgen blockade (CAB) treatment would result in metabolic changes of hippocampus and whether metabolic changes correlate with changes in cognitio...
Contextual factors matter: A two-year exploration into the impact of contextual factors on elite women’s rugby sevens match-play movement demands
Introduction and aims Women’s rugby sevens is a rapidly growing sport that imposes unique match-play movement demands on participants. This research investigated the effect of contextual factors on th...
Probing the intrinsic mechanism and evolution characteristics of online shopping customer satisfaction via text mining of online reviews
Prior research has tended to disregard the dynamic nature of customer satisfaction in online shopping and how it influences corporate marketing decisions. This study originally introduces a dynamic on...
Implementation of a surgical ward innovation: Telemonitoring controlled by healthdot [SWITCH-trial PROTOCOL]
Background Monitoring patients’ vital signs is important to detect abnormalities that may indicate a disturbed postoperative course. However, manual monitoring or so-called spot checks performed by nu...