PLoS ONE
Articles in this Issue
Research on the financial early warning models based on ensemble learning algorithms: Introducing MD&A and stock forum comments textual indicators
This study analyzes 284 publicly listed companies first designated as ST or *ST between 2015 and 2023. It utilizes two types of textual indicators: Management’s Discussion and Analysis (MD&A) and...
Boosting immune response against cervical cancer: A combined approach using oncolytic virus and targeted therapies
Background Cervical cancer remains a primary reason for cancer malignancy among women worldwide, primarily due to human papillomavirus (HPV) strains HPV16 and HPV18. Despite having access to vaccines,...
Identification of maternal allele sequences of IG-DMR that are essential for neonatal viability
The expression of imprinted genes in the Dlk1-Dio3 domain is regulated by Dlk1-Meg3 intergenic DMR (IG-DMR), which is methylated in a parental-of-origin-specific manner. An unmethylated 4.1-kb region...
Mental health and the role of social support in the lives of vulnerabilized sexual minority women
Introduction Sexual minority women (SMW; women who self-identify as lesbian, queer, etc., as well as heterosexually-identified women who experience attraction to romantic or sexual partnerships with w...
Relationship of urinary bisphenol A in childhood on thyroid hormone function in adolescents: a cohort study
Background Bisphenol A (BPA) is a type of endocrine-disrupting chemical utilized in the production of plastics like epoxy resins and polycarbonate polymers. BPA exhibits weak estrogenic and potent ant...
Occupational profile and prevalence of workplace accidents among beach workers
Background Workplace accidents (WAs) are acute, often preventable events that result in injuries or functional impairments, typically arising from occupation-related activities. In...
Effectiveness of thinner polyvinyl alcohol fibers on mechanical properties and cost effectiveness of office automation floor panels
Floor finishing is the final and crucial stage in building construction. Flooring materials must possess strength, insulation, durability, aesthetics, and comfort. Office buildings typically use raise...
Comprehensive safety assessment and therapeutic potential of Pediococcus acidilactici NMCC-B in attenuating arthritis progression
Dysbiosis of gut microbiota and loss of gut-barrier integrity contribute to the development and severity of rheumatoid arthritis (RA). The available treatments pose a burden of major adverse effects a...
Serum procalcitonin and procalcitonin clearance as a prognostic biomarker of sepsis in a pediatric critical care setting: A tertiary care experience 2016–2021
Background Sepsis remains one of the leading causes of morbidity and mortality in critically ill children worldwide. Identifying reliable prognostic markers is essential for improving risk stratificat...
New calculation model and application research on weak water-flushed zones distribution prediction in radial flow well patterns of heterogeneous oil reservoirs
After prolonged waterflooding development, the main integrated oil reservoirs in the X Oilfield have largely entered the late stage of waterflooding, with an average water cut reaching approximately 9...
Radio frequency interface quality assessment in 4G/5G: Effects of IQ imbalance, phase noise, and nonlinearities on error vector magnitude
Modern 4G/5G technologies aim to enhance data speeds, improve communication quality, and enable innovative services such as IoT and augmented reality. However, their efficiency depends on minimizing d...
The impact of diagnosis-related groups on medical costs, service efficiency, and healthcare quality in Meishan, China: An interrupted time series analysis
Background In January 2019, the Diagnosis-Related Groups (DRG) payment system was introduced in Meishan, China. Using the medical insurance records from 2017 to 2022, we evaluated the impact of the DR...
Stakeholders’ perspectives on the status of family planning integration into differentiated antiretroviral therapy service delivery models in Uganda: A qualitative assessment
Introduction Facility- and community-based differentiated antiretroviral therapy service delivery models (DSDM) for stable patients can offer a convenient platform for integrating self-care-oriented f...
Genome-wide association analysis and genomic selection for leaf-related traits of maize
Maize is an important food crop worldwide. The length, width, and area of leaves are crucial traits of plant architecture and further influencing plant density, photosynthesis, and crop yield. To diss...
Static network structure cannot stabilize cooperation among large language model agents
Large language models (LLMs) are increasingly used to model human social behavior, with recent research exploring their ability to simulate social dynamics. Here, we test whether LLMs mirror human beh...
Enhanced cadmium binding ability in response to novel modifications in a Paramecium cadmium metallothionein PMCd1
Metallothioneins (MTs) are low molecular weight cysteine rich proteins involved in detoxification of heavy metals. They are synthesized in response to metal exposure and can bind to various metals, th...
Performance of four newly released cassava varieties in a fallowed land over two cropping seasons
Cassava (Manihot esculenta Crantz) is an important crop for humans due to its staple and industrial values. Currently the demand is more than the supply as the current output falls below the expected....
An improved Red-billed blue magpie feature selection algorithm for medical data processing
Feature selection is a crucial preprocessing step in the fields of machine learning, data mining and pattern recognition. In medical data analysis, the large number and complexity of features are ofte...
Classification of fashion e-commerce products using ResNet-BERT multi-modal deep learning and transfer learning optimization
As the fashion e-commerce markets rapidly develop, tens of thousands of products are registered daily on e-commerce platforms. Individual sellers register products after setting up a product category...
Spatial patterns and clustering of dengue incidence in Mexico: Analysis of Moran’s index across 2,471 municipalities from 2022 to 2024
Dengue is an increasing public health challenge, with rising cases and expanding distribution. Its complex epidemiology is influenced by climate change, urbanization, and the circulation of multiple v...
Risk factors for multidrug-resistant and carbapenem-resistant Klebsiella pneumoniae bloodstream infections in Shanghai: A five-year retrospective cohort study
Background Multidrug-resistant Klebsiella pneumoniae (MDRKP) and carbapenem-resistant Klebsiella pneumoniae (CRKP) bloodstream infections (BSIs) account for significant mortality and healthcare costs....
Characterizing the particulate content of urine in healthy humans using flow cytometry
There is a notable scarcity of information concerning particulate matter in urine. This study presents an initial investigation that uses flow cytometry to determine the particulate content in the uri...
Correction: Impact of GnRH antagonist pretreatment on oocyte yield after ovarian stimulation: A retrospective analysis
To what extent does self-reported physical activity impact children’s wellbeing and mental health? Insights from school-aged children in Wales
There has been emphasis on the wellbeing of school-aged children amongst research, policy and practice in recent years, particularly during key developmental stages such as early childhood and adolesc...
Adapting COVID-19 research infrastructure to capture influenza and respiratory syncytial virus alongside SARS-CoV-2 in UK healthcare workers winter 2022/23: Results of a pilot study in the SIREN cohort
Introduction The combination of patient illness and staff absence driven by seasonal viruses culminates in annual “winter pressures” on UK healthcare systems and has been exacerbat...