PLoS ONE
Articles in this Issue
Real-world management, resource use, patient-reported outcomes and adherence in patients receiving direct oral anticoagulants for first stroke attributed to non-valvular atrial fibrillation in secondary care: A UK mixed-methods observational study
This real-world study investigated the patient-related factors, characteristics, and outcomes of adult patients with non-valvular atrial fibrillation (NVAF) receiving a direct oral anticoagulant (DOAC...
The differences of muscle activation in forehand serve-receiving technique of male tennis players at different skills
The purpose of this study was to analyze differences in muscle activation of the right upper limb and part of the trunk and differences in stroke performance of forehand receiving in male tennis playe...
Controlling factors for shale gas enrichment and their implications for favorable exploration areas: Insights from the Wufeng–Longmaxi Formations, Southern Sichuan, China
The exploration and development of shale gas in the Wufeng-Longmaxi Formations (WF-LMX FM) of the Southern Sichuan Basin exhibit pronounced spatial heterogeneity with 3–5 fold gas content variations i...
Factors associated with health decision-making autonomy on own healthcare among Tanzanian women: A 2022–2023 demographic health survey study
Background Women’s health decision-making autonomy is fundamental for the health and well-being of women and their children. It empowers women to make health decisions and exercise...
Characterization of blood microbial population in beef calves with clinical signs of sepsis using 16S rRNA gene sequencing
Sepsis, a dysregulated host response to infection, severely affects calf health. To date, sepsis diagnosis relies on clinical examination and positive blood culture. Differently, in humans 16S rRNA ge...
Health-related quality of life in Brazilian patients with cutaneous leishmaniasis using EQ-5D
Cutaneous leishmaniasis (CL) is a neglected infectious disease with a global distribution and a known health-related quality of life (HRQoL) impact. However, no utility-based HRQoL assessments for CL...
The impact of psychological distance on preferences for prenatal screening and diagnosis for chromosomal abnormalities: A hierarchical Bayes analysis of a discrete choice experiment
Introduction Hypothetical bias continues to be a primary challenge for stated preference methods. The source of hypothetical bias might be approached from the conceptual framework of “psychological di...
Transfer learning for mortality risk: A case study on the United Kingdom
This study introduces a transfer learning framework to address data scarcity in mortality risk prediction for the UK, where local mortality data is unavailable. By leveraging a pretrained model built...
Mortality rates in a cohort of infants attending immunization clinics in Uganda (2017–2019)
Background Uganda reported a significant reduction in the mortality rate of children under 5 years of age, from 146/1,000 live births in 2000–42/1,000 live births in 2021. With the rollout of Option B...
The impact of authentic leadership on the work engagement of primary and secondary school teachers: The serial mediation role of school climate and teacher efficacy
Background Teachers’ work engagement significantly impacts the overall teaching quality and educational effectiveness of a school. Previous research has identified authentic leadership, school climate...
Trends in Parkinson’s disease medication prescribing patterns in the UK: An interrupted time series analysis (2019–2024)
This study aimed to examine prescribing trends for Parkinson’s disease (PD) medications in the United Kingdom from 2019 to 2024, focusing on the impact of guidelines from the American Academy of Neuro...
Transmissible antimicrobial resistance in Escherichia coli isolated from household drinking water in Ibadan, Nigeria
Contaminated household water in peri-urban communities is a reservoir for virulent Escherichia coli , but its role in the environmental transmission of antibiot...
Real-world safety assessment of Ixekizumab based on the FDA Adverse Event Reporting System (FAERS)
Background Ixekizumab, a monoclonal antibody targeting IL-17A, is approved for psoriasis (PsO) and psoriatic arthritis (PsA). While clinical trials demonstrate its efficacy, real-world safety insights...
Identifying what matters to adults with mobility limitations regarding their experiences with medications: A concept mapping study
Background Despite the high prevalence of medication use among persons with mobility limitations, there are currently no patient-reported measures that have been co-developed to assess the experiences...
Social context influences Toxoplasma gondii and Trichinella spp. infection in Alberta free-roaming wild pigs (Sus scrofa)
The increasing spread of wild pigs across Canada is concerning due to their potential role as reservoirs for zoonotic diseases, including trichinosis and toxoplasmosis. Trichinosis is caused by the pa...
The accuracy of three-dimensional facial scan obtained from three different 3d scanners
This study aimed to compare the accuracy (trueness and precision) and reproducibility of three 3D facial scanning systems: a laser scanner (Planmeca Proface), a dual-structured light scanner (EinScan...
Prolonged secondary hyperparathyroidism in adenine-induced CKD leads to skeletal changes consistent with skeletal hyporesponsiveness to PTH
High circulating parathyroid hormone (PTH) leading to secondary hyperparathyroidism is proposed to be a key driver of the skeletal phenotype of chronic kidney disease-mineral bone disorder (CKD-MBD) l...
Chinese economic development difference factors empirical study
This article provides a detailed analysis and empirical support for the fiscal decentralization system, exploring its mechanisms in regulating the imbalance and insufficiency of regional economic deve...
Chemical composition and in vitro nutritional assessment of watermelon (Citrullus lanatus) plant silage as a forage option for Murciano-Granadina goats
Climate change is exerting significant negative impacts on various sectors, with livestock farming being particularly affected. One of the most pressing challenges in this context is the growing short...
Detecting eavesdropping nodes in the power Internet of Things based on Kolmogorov-Arnold networks
The rapid proliferation of the Power Internet of Things (PIoT) has given rise to severe network security threats, with eavesdropping attacks emerging as a paramount concern. Traditional eavesdropping...
Protocol for Japan–acute retinal necrosis (J-ARN) registry: A combined prospective and retrospective cohort study
Background Acute retinal necrosis (ARN) is a rare but vision-threatening viral retinitis that can lead to severe visual impairment or blindness if not diagnosed and treated promptly. However, due to i...
Leveraging transformers and explainable AI for Alzheimer’s disease interpretability
Alzheimer’s disease (AD) is a progressive brain ailment that causes memory loss, cognitive decline, and behavioral changes. It is quite concerning that one in nine adults over the age of 65 have AD. C...
Empirical analysis of COVID-19 confirmed cases, hospitalizations, vaccination, and international travel across Belgian provinces in 2021
In the absence of definitive treatments or vaccines, the primary strategy to mitigate the COVID-19 pandemic relied on non-pharmaceutical interventions. By the end of 2020, COVID-19 vaccines had been d...
Identification of risk factors for supra-therapeutic vancomycin trough levels in ventilator-assisted critical care patients based on integrated modeling and multi-criteria decision analysis
To explore the risk factors influencing vancomycin trough concentration (Cvg−min) overexposure in critically ill patients with mechanical ventilation and rank the factors, the medical records of 194 m...
The motivation and consequence of fact-checking behavior: An experimental study
In a series of online experiments, we asked people to evaluate news veracity and varied two experimental conditions: (1) the opportunity to receive fact-checking results and (2) bonus payment for accu...