PLoS ONE
Articles in this Issue
Impact of Diagnosis-Intervention Packet (DIP) reforms on inpatient services for low-income populations in central China: A multi-stage interrupted time-series analysis
As global healthcare costs continue to rise, concerns about health equity have become increasingly prominent. In response, China introduced the Diagnosis-Intervention Packet (DIP) reform in 2021 to op...
Awareness and willingness to utilize HIV pre-exposure prophylaxis and associated factors among men who have sex with men in Maanshan, China
Objective Men who have sex with men (MSM) are disproportionately affected by HIV and represent the primary target population for pre-exposure prophylaxis (PrEP) use. However, PrEP adoption in China re...
Exploring user experience: A qualitative analysis of the use of a physical activity support app for people with heart failure
Introduction Heart failure (HF) is a prevalent and debilitating global health issue, affecting approximately 65 million people worldwide. Physical activity is recommended for HF management, yet many p...
Canadian natural science graduate stipends lie below the poverty line
Despite the critical role of graduate students in the Canadian research ecosystem, students report high levels of financial stress. As a case study, we collected graduate minimum stipends and tuition...
EFCRFNet: A novel multi-scale framework for salient object detection
Salient Object Detection (SOD) is a fundamental task in computer vision, aiming to identify prominent regions within images. Traditional methods and deep learning-based models often encounter challeng...
Progression of keratoconus in the contralateral eye following acute corneal hydrops: A retrospective study
Keratoconus is a progressive eye disease characterised by thinning and bulging of the cornea, leading to distorted vision. Acute corneal hydrops, a rare and severe complication of keratoconus, occurs...
The role of product art design based on a fuzzy decision support system in improving user interaction experience
User interaction for product selection relies on its design and technical support to improve the quality of the experience. Decision support systems are incorporated to leverage user experience throug...
“It’s a kind of double-edged sword”: exploring the social media-related experiences of adults with visible differences using photo-elicitation interviews
Objectives Visible differences are associated with experiences of stigma, discrimination, anxiety, and social isolation. Social media provides a space to connect with others with the same condition, g...
Therapeutic potential of fisetin in hepatic steatosis: Insights into autophagy pathway regulation and endoplasmic reticulum stress alleviation in high-fat diet-fed mice
Non-alcoholic fatty liver disease (NAFLD) is a common condition with limited FDA-approved treatments due to its complex pathogenesis. Metabolic stress-induced lipotoxicity triggers the unfolded protei...
Environmental DNA illuminates the darkness of mesophotic assemblages of fishes from West Indian Ocean
The advent of environmental DNA (eDNA) represents a pivotal advancement in probing mesophotic communities, offering a non-intrusive avenue for studying marine biodiversity at greater depths. Using thi...
Rhus vulgaris Meikle fruit-mediated silver nanoparticles: Synthesis, characterization, and potential for sun protection, antioxidant and antibacterial applications
This study investigates the synthesis of silver nanoparticles (AgNPs) using Rhus vulgaris fruit extract (RVFE) and evaluates their antioxidant, antibacterial, and UV protection properties. R. vulgaris...
Comparative analysis of influenza healthcare disparities in the United States using retrospective administrative claims from Medicaid and commercial databases, 2015–2019
Background Influenza-related healthcare utilization among Medicaid patients and commercially insured patients is not well-understood. This study compared influenza-related healthcare utilization and a...
Correction: A natural history study to track brain and spinal cord changes in individuals with Friedreich’s ataxia: TRACK-FA study protocol
AntBot-EX: Enhancing robot search efficiency in complex post-disaster environments
In post-disaster scenarios, effective rescue operations hinge on deploying robots equipped with sophisticated path planning algorithms capable of navigating through complex and unknown environments, f...
β-glucan induced trained immunity enhances antibody levels in a vaccination model in mice
Trained immunity improves disease resistance by strengthening our first line of defense, the innate immune system. Innate immune cells, predominantly macrophages, are epigenetically and metabolically...
Utilizing Theory of Planned Behaviour to increase intention to participate in hepatitis C treatment therapy among Methadone maintenance therapy clients (MMT) in Malaysia: A cluster randomised control trial
Introduction The World Health Organization (WHO) has targeted eliminating viral hepatitis as a public health problem by 2030. Thus, high-risk groups such as Methadone Maintenance Therapy (MMT) clients...
A retrospective analysis of prenatal genetic results in fetal hydronephrosis
Objective To discuss the application value of technologies such as chromosome microarray analysis (CMA) in fetuses with hydronephrosis and pyelectasis. Methods Retrospectively collected the prenatal...
An unfortunate natural experiment in learning how to provide services to those in need: The case of Ukrainian war refugees with disabilities in Warsaw and Bucharest
When helping others, experience becomes important, especially in circumstances that involve interacting with different cultures—such as providing services to refugees. When disability is added to refu...
AISIM: evaluating impacts of user interface elements of an AI assisting tool
While Artificial Intelligence (AI) has demonstrated human-level capabilities in many prediction tasks, collaboration between humans and machines is crucial in mission-critical applications, especially...
Strategies to assess and promote the socio-emotional competencies of university students in the socio-educational and healthcare fields: A scoping review
This scoping review systematically analyses and synthesises empirical evidence on measures and intervention programmes aimed at promoting socio-emotional competencies (SECs) in university students in...
The structure of spontaneous speech changes in Alzheimer’s disease: Crosslingual evidence from English and Greek
Impairment in the semantic domain is prominent in Alzheimer’s Disease (AD). We analyzed spontaneous speech in English from 148 people with probable AD (pAD) and 143 controls, and aimed to replicate th...
Cytogenetic changes in Rosa spinosissima L. and Leymus angustus (Trin:) Pilg. growing under radioactive contamination conditions at the Semipalatinsk nuclear test site
In this study, we investigated the cytogenetic effects of exposure to chronic radioactive contamination on the populations of Rosa spinosissima L. and Leymus angustus (Trin.) Pilg. growing in fields a...
Transfer learning of neural operators for partial differential equations based on sparse network λ-FNO
When the solution domain, internal parameters, and initial and boundary conditions of partial differential equation (PDE) are changed, many potential characteristics of the equation’s solutions are st...
Clinical evolution and medical resource utilization in adult patients with respiratory syncytial virus infection at a community hospital in Argentina
Objective To describe the hospital medical resources used in adults hospitalized with respiratory syncytial virus infection and to evaluate the association of comorbidities with re...
Predicting the sport level in elite male motorcycle speedway riders based on physical profile and experience
The main objective of this research was to analyze the physical profile and experience of elite male motorcycle speedway riders, in order to develop a mathematical model to predict their level of spor...