PLoS ONE
Articles in this Issue
The mind & muscles: Introducing a validated EEG/EMG protocol for recording cognitive-muscular interactions in experimental archaeology
Despite extensive research into the biomechanical and cognitive dimensions of early hominin material culture, no study has explored these aspects together in the context of stone tool production and u...
Determinants of gestational weight gain during pregnancy in a multiethnic UK-based population: Findings from the Born in Bradford cohort study
Introduction Unhealthy maternal weight gain during pregnancy is associated with deleterious outcomes to mothers and their offspring. Current literature on the determinants of gestational weight gain y...
Evaluating the effectiveness of data governance frameworks in ensuring security and privacy of healthcare data: A quantitative analysis of ISO standards, GDPR, and HIPAA in blockchain technology
Blockchain technology is widely used in almost every domain of life nowadays including healthcare sector. Although there are existing frameworks to govern healthcare data but they have certain limitat...
Development and validation of a questionnaire assessing pharmacists' knowledge and practice towards antimicrobial stewardship in oncology care
Background Cancer patients who receive immunosuppressive therapy are vulnerable to infections due to their compromised immune systems. Therefore, research in promoting the prudent use of antibiotics i...
LI-YOLOv8: Lightweight small target detection algorithm for remote sensing images that combines GSConv and PConv
In the domain of remote sensing image small target detection, challenges such as difficulties in extracting features of small targets, complex backgrounds that easily lead to confusion with targets, a...
Neuronal number and somal volume in calbindin-expressing neurons of the marmoset dorsal lateral geniculate nucleus are preserved during aging
Compelling evidence links age-related brain dysfunction and neurodegenerative processes to persistent disruptions in intracellular calcium (Ca2+) signaling, a central hypothesis in the Ca2+ theory of...
Carbonic anhydrase IX downregulation linked to disruption of HIF-1, NFκB and STAT3 pathways as a new mechanism of ibuprofen anti-cancer effect
Numerous studies have highlighted the anti-cancer effects of nonsteroidal anti-inflammatory drugs (NSAIDs), although the underlying mechanisms remain unclear. This study focuses on elucidating the imp...
A lightweight hyperspectral image multi-layer feature fusion classification method based on spatial and channel reconstruction
Hyperspectral Image (HSI) classification tasks are usually impacted by Convolutional Neural Networks (CNN). Specifically, the majority of models using traditional convolutions for HSI classification t...
Trends, geographic distribution, and disease burden of bipolar disorder in Ecuador (2011–2021): An analysis of hospital discharge data
This retrospective observational study aims to evaluate the incidence, disease burden, and geographic distribution of bipolar disorder based on hospital records in Ecuador over an eleven-year span. Ho...
Establishment of a neonatal resuscitation registry in the Democratic Republic of the Congo: An open cohort study
Improving neonatal resuscitation practices reduces neonatal mortality. In low- and middle-income countries (LMICs), granular details about provider actions during resuscitation are largely unknown; th...
Pupil responses to melanopsin-isolating stimuli as a potential diagnostic biomarker for glaucoma
Purpose To test whether differences in pupil responses to melanopsin-isolating spectral stimuli in glaucoma may be useful as a diagnostic biomarker. Methods Spectral stimuli were presented to 20 gla...
Forecasting monthly runoff in a glacierized catchment: A comparison of extreme gradient boosting (XGBoost) and deep learning models
Accurate monthly runoff forecasting is vital for water management, flood control, hydropower, and irrigation. In glacierized catchments affected by climate change, runoff is influenced by complex hydr...
Clinical profile of alcohol dependent paintents according to Lesch Typology one year after the Covid-19 pandemic-comparative study
Background The COVID-19 pandemics caused both physical and mental health problems raising global social tension, anxiety and discomfort which toghether lead to the increase in the consumption of psych...
Convolutional neural network using magnetic resonance brain imaging to predict outcome from tuberculosis meningitis
Introduction Tuberculous meningitis (TBM) leads to high mortality, especially amongst individuals with HIV. Predicting the incidence of disease-related complications is challenging, for which purpose...
Correction: Influences of atmospherics on customer satisfaction and behavioural intentions in the restaurant industry: Evidence from an emerging economy
Single immersion in cold water below 4 °C: A health hazard in young healthy men?
The circulatory system plays a significant role in the adaptation of the human body to varying environmental conditions and stress factors, such as cold water immersion. The aim of the study was to de...
Determinants of general health perception among individuals with chronic low back pain overtime: structural equation modeling
Background Low back pain (LBP) is a public health problem. General health perception is the best predictor of healthcare utilization and mortality. Identifying predictors of health perception helps un...
Serological evidence and factors associated to liver damage in malaria-typhoid infected patients consulting in two health facilities, Yaoundé-Cameroon
Malaria and typhoid fever remain major health issues in developing countries like Cameroon, with frequent co-infections. The potential liver damage caused by their respective causative pathogens is ov...
Mortality in severe serious adverse events following heterologous and homologous prime-boost vaccination strategies for SARS-CoV-2: A retrospective cohort study
The COVID-19 pandemic underscored the urgent need for widespread vaccination to achieve herd immunity and mitigate severe outcomes. To address vaccine supply constraints, heterologous prime-boost stra...
Differentiation of European yellow rust subraces within the ‘Warrior(-)’ genetic group
Wheat yellow rust is one of the most destructive and rapidly evolving wheat diseases worldwide, particularly in Europe. In 2011, the previously clonal European yellow rust races were replaced by a pre...
Risk formulation mechanism among top global energy companies under large shocks
Taking top global energy companies as the epitome, this paper investigates the risk formulation mechanism of the international energy market under the impact of large shocks. We first use the machine...
Optimization of the viability PCR for accurate detection of Staphylococcus aureus in food samples
Staphylococcus (S.) aureus is a prominent foodborne pathogen that can cause food poisoning due to its staphylococcal toxins. Controlling the viable levels of S. aureus is crucial for ensuring food saf...
Divergent impacts of glycemic control on mortality and complications in patients with early-versus late-onset type 2 diabetes: A retrospective cohort study
Aims To investigate whether optimal glycemic control is associated with all-cause mortality, cardiovascular disease mortality, diabetes-related mortality, cancer-related mortality, and complications a...
Impact of obesity on follicular fluid lipid composition and IVF/ICSI outcomes in Korean women: A lipidomic study
Background Obesity negatively affects reproduction and in vitro fertilization (IVF) outcomes. However, its effects on lipid metabolism during embryonic development remain unclear. We examined follicul...
Ferrofluid droplet generation on a zero-thickness nozzle by a magnetic field using a wedge-shaped functional surface
Digital microfluidics for ferrofluids enables the manipulation of discrete droplets on open surfaces and has garnered significant interest as an alternative to traditional continuous-flow microfluidic...