PLoS ONE
Articles in this Issue
Does competitive position matter: Investigating the impact of information risk on COE and corporate investment
Purpose The purpose of this study is to find out how firm’s competitive position plays the moderating role between the relation of information risk and COE. The study considers the effect of two diffe...
Exploring the level of metabolic reprogramming and the role of prognostic factor SF3A3 in hepatocellular carcinoma through integrated single-cell landscape analysis
This study aims to investigate metabolic reprogramming heterogeneity in hepatocellular carcinoma (HCC) cells and identify novel therapeutic targets for HCC treatment. Single-cell RNA sequencing data f...
Antiviral potential of proton-type zeolite
This study reports the potent antiviral ability of proton-type zeolites without the aid of any metal cations. Antiviral activities of zeolites with different topologies and chemical compositions are i...
The role of novel biomarkers in the early diagnosis of pancreatic cancer: A systematic review and meta-analysis
Background Early detection of pancreatic cancer is essential for improving survival rates. However, noninvasive diagnostic methods are lacking. Novel biomarkers, detectable through liquid biopsy, such...
Visual attention and response time to distinguish athletes from non-athletes: A virtual reality study
In recent years, cutting-edge technologies have been increasingly integrated into sports to assess physical and cognitive capacities. Virtual Reality (VR) technology has emerged as a powerful tool, of...
Bioinformatics and system biology approach to discover the common pathogenetic processes between COVID-19 and chronic hepatitis B
Introduction The ongoing coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), presents a significant global public health threat. C...
A multi-scale observation and crack statistics based method for analyzing failure mechanism of pre-flawed rock under true triaxial stress
Understanding the failure mechanism of the rock mass under the general stress state is of great importance for the safe constructions of the underground engineering. Here, a series of true triaxial fr...
Development and validation of mass reduction prediction model during torrefaction using biomass chemical composition analysis
Thermochemical processes employ heat to transform biomass into energy. In these processes, heat supply and biomass type can affect the products, therefore understanding them is critical. Confirming th...
Landslide hazard early warning method for rock slopes using a hybrid LSTM-SARIMA data-driven model
Rock slope landslides are characterized by their sudden onset and significant destructive power, posing a major threat to human life as well as the safety of equipment and infrastructure.Currently, re...
A multiscale comprehensive index for evaluating the development level of surface granite discontinuities
The Gansu Beishan area is a preselected candidate site for a high-level radioactive waste repository in China. The development of surface rock mass discontinuities in this region is crucial for ensuri...
Promoting the modal shift of freight from road to rail in China: An evolutionary game and simulation study
In the context of China’s road to rail policy, this study constructs a tripartite evolutionary game model to mathematically investigate the strategic interactions among local governments, railway tran...
A human antibody specific for SIRPα reprograms macrophages and promotes antibody mediated anti-cancer activity
Several T cell immune checkpoint blockade therapies have shown initial successes in multiple cancers. However, significant issues remain, including tumor relapse, severe toxicities, and a lack of effi...
Association between aspartate aminotransferase to alanine aminotransferase ratio and 28-day mortality of ICU patients: A retrospective cohort study from MIMIC-IV database
Background Prior studies have linked the aspartate aminotransferase to alanine aminotransferase ratio (AAR) with negative health outcomes in the elderly and specific populations. However, the impact o...
Involvement of community pharmacy pharmacists in fecal immunochemical test screening without government support in Japan
Colorectal cancer (CRC) is the third most common malignancy and second leading cause of death worldwide. However, the screening rate, which is a typical preventive measure, remains low. A community ph...
A lithium-ion batteries SOH estimation method based on extracting new features during the constant voltage charging stage and improving BPNN
Existing state of health (SOH) estimation methods for lithium-ion batteries predominantly extract health features (HF) from constant current (CC) and constant voltage (CV) charging phases. Nevertheles...
Shaping the future of medical education: A cross-sectional study on ChatGPT attitude and usage among medical students in Sudan
Background Artificial intelligence (AI) is revolutionizing education globally, yet its adoption in medical education remains inadequately understood. ChatGPT, a generative AI tool, offers promising ye...
Analysis of functional brain connectivity in patient with end-stage kidney disease undergoing peritoneal dialysis using functional near infrared spectroscopy
Introduction Neurological complications are common in patients with end-stage kidney disease (ESKD). However, the mechanisms underlying neurological complications of ESKD are poorly understood. Resear...
Bovine pain scale: A novel tool for pain assessment in cattle undergoing surgery in the hospital setting
Pain negatively impacts animal welfare and it is still neglected in ruminants. This original study aimed to develop and validate the Bovine Pain Scale (BPS) for acute pain assessment in hospitalized c...
Enzymatic saccharification of peat polysaccharides is limited by accessibility
Sphagnum peat bogs store a large fraction of biologically-bound carbon, due to a steady accumulation of plant material over millennia. The resistance of Sphagnum biomass to decay is poorly understood...
Probability-based adaptive capacity rental strategy on shared platform with unknown demand distribution
Capacity sharing presents a transformative strategy in manufacturing, driven by the increasing demand for flexibility and efficiency in a highly uncertain market. Shared platforms play a crucial role...
Continuous approximation and GIS-enhanced design optimization of feeder bus networks along rail corridors
As urbanization accelerates, urban public transportation systems are tasked with meeting the growing demand for travel. According to statistics, the regional rail transit network currently handles 60%...
Surgical techniques and outcome assessment of a novel vascularized orthotopic rodent whole eye transplantation model
Currently there are no surgical solutions to restore vision in the irreversibly blind. Whole eye transplantation (WET), is an appealing surgical approach for restoration, replacement, and reconstructi...
Clinical outcomes and management of tibial plateau fractures in Ethiopia: A prospective cohort study
Background Tibial plateau fractures, accounting for approximately 1% of adult fractures, are often associated with significant long-term complications such as pain, stiffness, and posttraumatic arthro...
Risk assessment of arteriovenous fistulas focusing on the relationships between the properties of shunted blood flow sounds and a medical/surgical history of hemodialysis patients
The global prevalence of end-stage kidney failure is increasing, with hemodialysis as the primary treatment. An arteriovenous fistula serves as a critical lifeline for patients undergoing hemodialysis...
Appropriate data segmentation improves speech encoding models: Analysis and simulation of electrophysiological recordings
Background: In recent decades, studies modeling the neural processing of continuous, naturalistic, speech provided new insights into how speech and language are represented in the brain. However, the...