PLoS ONE
Articles in this Issue
Scent of death: Emission and behavioral role of 1-nonene in entomopathogenic nematode Steinernema kraussei
Entomopathogenic nematodes (EPNs) provide a natural alternative to synthetic pesticides for pest control. Understanding how EPNs respond to volatile cues including those released by infected cadavers...
Vaccination status and its determinants among children aged 12–23 months in Tigray, northern Ethiopia: A zero-inflated Poisson regression analysis
Background In Tigray, immunization services have been severely interrupted, and cases with vaccine preventable diseases become rampant due to the conflict. However, there is limited evidence on the st...
The association between TyG index and hypertension in middle-aged and elderly Chinese patients: Data from CHALRS
Background The TyG index is thought to be a trustworthy substitute indicator of insulin resistance. Increasing research evidence shows the correlation between TyG and various cardiovascular and cerebr...
A multi-time scale rolling optimization framework for low-carbon operation of CCHP microgrids with demand response integration
Microgrid systems incorporating carbon trading mechanisms and demand response (DR) demonstrate significant potential for facilitating low-carbon societies and advancing sustainable energy development....
Non-linear association between life’s essential 8 score and depression in middle-aged and older adults with chronic obstructive pulmonary disease
Objective Relatively few studies have investigated the link between the Life’s Essential 8 (LE8) score and depression among individuals with Chronic Obstructive Pulmonary Disease (COPD). Our objective...
Intelligent surgical drainage - digitizing the analysis of drainage fluid in patients with surgical drains
Surgical drains are essential in post-operative care, where timely removal is critical to prevent complications. Early removal can result in seromas and hematomas, while delayed removal may lead to in...
Assessing biomarker trajectories for mortality risk in peritoneal dialysis: A focus on multivariate joint modeling
This study investigates mortality risk prediction in peritoneal dialysis (PD) patients through longitudinal biomarker analysis, comparing traditional and advanced statistical approaches. A retrospecti...
The pattern of lung function tests in children with sickle cell disease: A case-control study
Background Sickle cell disease (SCD) is major inherited disease linked to a pro-inflammatory state, with a widespread involvement seen in all organ systems with lungs being no different. This research...
The influence of digital professional development and professional learning communities in the relationship between school digital preparedness and digital instructional integration
Integration of digital tools and resources in STEM instruction has garnered significant attention due to its high potential. Digital professional development and professional learning communities are...
Recombinant human alpha-N-acetylglucosamine-6-sulfatase delivered to Sanfilippo D mice with repeated intracerebroventricular injections corrects CNS pathology
Mucopolysaccharidosis type IIID (MPS IIID; Sanfilippo D) is caused by biallelic pathogenic variants in N-acetylglucosamine-6-sulfatase (GNS), which participates in catabolism of heparan sulfate (HS) g...
Tooth ARcademy: A mobile app for teaching and learning of oral histology
m-Learning is gaining popularity in health professional education; however, reports on mobile apps targeting didactic teaching and learning are scarce, particularly in the context of health profession...
Quantitative assessment method for firefighting danger based on numerical simulation of forest fire spread in canyon wind fields
Forest firefighting incidents frequently occur in mountainous and canyon regions which are characterized by complex topography, primarily because of variable local wind patterns that create conditions...
Study on deformation characteristics and crack extension law of cement stabilized phosphogypsum materials under dry and wet cycles
The resource utilization of phosphogypsum has been a worldwide problem. Previous research was limited to mixing phosphogypsum with other materials (lime, gravel, red clay) to play an auxiliary role ra...
Evaluating the long-term strength of GGBFS-blended cement across various water-to-binder and superplasticizer ratios under heating/cooling cycles
The investigation is to understand the combined effects of ground granulated blast furnace slag (GGBFS) content, superplasticizer (SP) dosages, and water-to-binder (w/b) ratios on the fresh and harden...
Identification of glutathione transferase (GST P1) inhibitors via a high-throughput screening assay and implications as alternative treatment options for breast cancers
Glutathione S-transferase P1-1 (GST P1) is an important drug target as it is implicated in drug resistance. GST P1-1 inhibitors are typically non-productive analogues of glutathione which covers broad...
High acceptability of newborn screening for sickle cell disease among post-natal mothers in Western Kenya
Sickle cell disease is a genetically inherited blood disorder that manifests early in life with resultant significant health complications. Globally, nearly three quarters of all affected babies are i...
The role of advanced glycation end products (AGEs) and the receptor for AGEs (RAGE) in hypertrophic obstructive cardiomyopathy
Background Advanced glycation end products(AGEs)/RAGE(receptor for AGEs) play divergent roles in cardiovascular disease. Our study is to evaluate the correlation between AGEs/RAGE in circulation (solu...
Effects and predictors of intravenous lidocaine infusion for patients with fibromyalgia
Objective Fibromyalgia is a chronic pain condition characterised by widespread pain. The current treatment primarily focuses on self-management and symptomatic relief. IV lidocaine...
Polymorphisms in MTNR1A (rs2119882) and CLOCK (rs1801260) genes are associated with facial acne susceptibility in gas station workers
This study aimed to explore the relationship between circadian rhythm gene polymorphisms, specifically MTNR1A rs2119882 and CLOCK rs1801260, and the risk of acne in an occupational population. MTNR1A...
Mediation analysis of depressive symptoms in the relationship between pulmonary function (measured by peak expiratory flow) and cognitive function among older adults in Chinese
Background Population aging has led to accelerated decline in pulmonary function, rising prevalence of depressive symptoms, and cognitive impairment, posing significant public health challenges. Altho...
Human whole blood influences the expression of Acinetobacter baumannii genes related to translation and siderophore production
Acinetobacter baumannii is a major cause of bloodstream infections, yet its adaptation and survival mechanisms in human blood remain poorly understood. While previous studies focused on individual blo...
Diatom diversity and distribution in Neotropical karst lakes under anthropogenic stress
Lake degradation is an important environmental problem in the Neotropics, where rapid population growth is leading to increasing human impact. However, baseline studies in these lakes are still scarce...
Expression of Concern: Prevalence and associated factors of needle stick and sharps injuries among healthcare workers in Northwestern Ethiopia
From sole crops to strip cropping: Decision rules of frontrunner farmers in The Netherlands
Strip cropping, where several crops are grown in adjacent long and narrow multi-row strips, is an innovation niche that challenges monocropping by offering a greater range of ecosystem services, inclu...
Increased gut microbiota diversity in women with uterine fibroids: Insights from a pilot study on gut and reproductive tract microbiota
Uterine fibroids (UFs) are still mysterious lesions, they are influenced by hormonal imbalances and chronic inflammation, with recent emerging evidence suggesting a role for microbiota. While gastroin...