PLoS ONE
Articles in this Issue
Characterization and bioactivity potential of marine sponges (Biemna fistulosa, Callyspongia diffusa, and Haliclona fascigera) from Kenyan coastal waters
Sponges have been reported as a rich source of bioactive compounds, which could potentially be developed into lead compounds for pharmaceutical use. The present study aimed to identify sponges and ass...
What makes a specialised emergency plan effective?—A case study of railway operation in 33 prefectural cities in China
Emergency response plans play a crucial role in mitigating safety risks associated with urban rail transport operations and effectively responding to emergencies in underground spaces. This study eval...
Integrating customer-based brand equity and the theory of planned behavior to predict electric vehicle adoption in China: The moderating role of perceived price
Despite burgeoning global sustainability efforts, the widespread adoption of electric vehicles (EVs) in China faces persistent hurdles, highlighting a critical need to unravel the intricate psychologi...
Enhancing tuberculosis treatment support: A thematic analysis of interactive messages in a digital adherence technology trial to identify needs, challenges, and strategies for improvement
Background Digital adherence technologies (DATs) offer promising solutions for monitoring and supporting adherence to complex treatment regimens, including tuberculosis (TB) treatment. However, better...
Association between albumin and short-term outcomes of unplanned early readmission emergency department patients: A retrospective cohort study
Objective This study was a post hoc analysis of data from a retrospective cohort population. The purpose of this study was to analyze the predictive value of albumin for the short-term survival of pat...
Effect of community-led total sanitation on open defecation in Uganda: A propensity score-matched analysis
A substantial proportion (7%) of people in Uganda practice open defecation. A Community-Led Total Sanitation (CLTS) project was started in 2011 to reduce indiscriminate disposal of excreta but the eff...
“The message hurts, but it would be worse if nothing was said” – Communicating severe illness and the imminence of death to patients with end stage heart failure and their families – A longitudinal interview study
Aims Discussions about severe illness and the coming death do not often take place with patients with heart failure and their family. We therefore aimed to investigate how patients with end-stage hear...
Genetic diversity and relationships of broomcorn millet based on trnT-trnL and GBSSI sequences
Broomcorn millet (Panicum miliaceum L.) is the oldest crop originating in China. The routes of transmission have been the focus of broomcorn millet research. This study evaluated genetic diversity and...
Latent class analysis of aggression in martial arts and combat sports: A cross-sectional study
Previous research on aggression in martial arts and combat sports (MA&CS) has shown mixed results. Some studies showed that MA&CS training lowers aggression levels, while other studies found i...
Effects of physical exercise during pregnancy on delivery outcomes: Systematic review and meta-analysis of randomized controlled trials
Background Pregnant women should engage in a range of physical activities as it is not only safe but also has many maternal benefits. This systematic review and Meta -analysis aimed to assess the pool...
Correction: StructuRly: A novel shiny app to produce comprehensive, detailed and interactive plots for population genetic analysis
Integrative analysis of co-expression networks and codon usage bias in maize under biotic stress
Understanding the complex networks underlying the biotic stress response in maize is crucial for developing effective approaches to improve tolerance. We identified 1449 differentially expressed genes...
Understanding the action of bamocaftor as a potential drug candidate against Cystic Fibrosis Transmembrane Regulator protein: A computational approach
Cystic Fibrosis (CF) is a hereditary condition and can cause permanent respiration problems leading to degraded life quality. The most common variation leading to CF is the F508del variation. CF can c...
A role for Myo-II zipper and spaghetti squash in Gliotactin-dependent Drosophila melanogaster wing hair planar cell polarity
Planar cell polarity, polarization in the plane of an epithelium, is critical for tissue development. The Drosophila melanogaster wing epithelium is an important model system for planar cell polarity...
It takes two to tango: A directed two-mode network approach to desirability on a mobile dating app
Using digital traces from online dating presents the opportunity to study the earliest stages of human mating. We focus on whether online dating app users are homophilic in terms of the desirability o...
Benthic biofilm structure and function under abrupt flow changes
Sediment accumulation reduces the capacity of dammed systems worldwide, therefore understanding sediment stability and transport within a reservoir is fundamental for sustainable management. Fluctuati...
The harmful effects of legislative restrictions on gender affirming hormone therapy in Florida and Missouri: Challenges for patients and providers
Among the recent surge of legislative restrictions on the provision of gender affirming care to youth in the United States, some legislation, such as bills passed in 2023 in Florida and Missouri, have...
Impact of climate change on Boro rice production in Bangladesh: Evidence from time series modeling
Bangladesh has three distinct rice-growing seasons: Aus, Aman, and Boro, each with its distinct climatic state. Climatic factors interacting with non-climatic factors impact seasonal rice yield. Howev...
Analysis of wet and dry encounters in the Yangtze River Basin based on the Copula function family and research on the probability of floods and droughts occurrence
As the largest river in China, exploring the evolution characteristics of rainfall in the upper, middle, and lower reaches of the Yangtze River and analyzing the frequency of wet and dry encounters pl...
The effect of government publicity and guidance on farmers’ ecological environment governance participation behavior—The mediating effect of environmental literacy and perceived value
As an important policy tool for rural ecological environment governance, it is crucial to clarify the mechanism through which government publicity and guidance affects farmers’ participation behavior,...
TunR2, a novel mode-of-action tunicamycin-type antibiotic: Pharmacokinetics in C57BL/6 mouse and Holstein cattle
We have investigated the pharmacokinetics of TunR2, a modified tunicamycin-type antibiotic, in mice and cattle. TunR2 has previously been shown to be effective in a mycobacterial disease model using z...
Naps, night-time sleep and cognitive function among middle-aged and older people in China
Background There is increasing interest in how sleep affects cognitive function; however, the combined impact of naps and night-time sleep on different cognitive domains is still not well understood....
The rise of open data practices among bioscientists at the University of Edinburgh
Open science promotes the accessibility of scientific research and data, emphasising transparency, reproducibility, and collaboration. This study assesses the Openness and FAIR (Findable, Accessible,...
Association of triglyceride-glucose index and estimated glucose disposal rate with outcomes in patients with acute myocardial infarction: Cumulative effect and mediation analysis
Background The triglyceride-glucose (TyG) index and the metabolic score for insulin resistance (METS-IR) are insulin resistance indicators based on different metabolic parameters. However, their cumul...
Statistical testing and spatio-temporal evolution characteristics of the coupling coordination between green agricultural production efficiency and food security
Under the requirements of developing new quality productivity, balancing green agricultural development with food security has become crucial for sustainable development, particularly in regions facin...