PLoS ONE
Articles in this Issue
Dynamic complexity of Stackelberg-Bertrand game with one-way R&D spillovers, effective information and government subsidies
The phenomena of bounded rationality, asymmetric information, research and development (R&D) spillovers represent ubiquitous characteristics in economic systems, yet research simultaneously invest...
Optimal multi-objective energy management of decentralized demand response incorporating uncertainties
This paper presents a decentralized demand response (DR) framework that, incorporating optimal multi-objective energy management strategies, addresses uncertainties in power networks. The power indust...
Does tinnitus and emotional distress influence central auditory processing? A comparison of acute and chronic tinnitus in normal-hearing individuals
Objective Tinnitus is characterized by the perception of sound without an external source and can cause auditory difficulties even in individuals with normal hearing. Design This study compared the...
Enhancing functional motor outcomes in chronic stroke: A systematic review of the growing role of non-invasive brain stimulation
Introduction Non-invasive brain stimulation (NIBS) promotes functional recovery by enhancing neuroplasticity and reorganizing brain networks. It is hypothesized that transcranial magnetic stimulation...
On-treatment blood pressure and dose-dependent effects of ARNI in heart failure with reduced ejection fraction: Insights from a multicenter registry
Background Achieving target doses of angiotensin receptor-neprilysin inhibitor (ARNI) in heart failure with reduced ejection fraction (HFrEF) is often challenging due to concerns related to hypotensio...
Surgical preferences in anterior cruciate ligament reconstruction: A cross-sectional study in a low-middle income country
Introduction Anterior cruciate ligament reconstruction (ACLR) is one of the most common surgical procedures in sports orthopedics; however, there is a lack of literature related to this topic in Peru....
Protocol for the Redefining Maternal Anemia in Pregnancy and Postpartum (ReMAPP) study: A multisite, international, population-based cohort study to establish global hemoglobin thresholds for maternal anemia
Background Anemia affects one in three pregnant women worldwide, with the greatest burden in South Asia and sub-Saharan Africa. During pregnancy, anemia has been linked to an increased risk of adverse...
Speaker differences in volitional voice modulation reflected in empathy and functional activation patterns
How we use our voice is central to how we express information about ourselves to others. A speaker’s dispositional social reactivity might contribute to how well they can volitionally modulate their v...
Associations between the red blood cell distribution width-to-albumin ratio and 3-month outcomes in patients with acute minor ischemic stroke: A cohort study
Acute minor ischemic stroke (AMIS) patients may experience unfavorable outcomes despite mild initial symptoms. The ratio of red blood cell distribution width (RDW) to albumin (ALB) (RAR) has been asso...
Identification of risk factors and development of a predictive model in patients using cefmetazole for international normalized ratio elevation
Patient risk factors related to coagulopathy and bleeding when using cefmetazole (CMZ) have not yet been identified, and no models exist to predict side effects during CMZ treatment. Moreover, reports...
Response Gene to Complement 32 promotes cell proliferation and tamoxifen resistance in breast cancer via elevated FoxM1 expression
Despite the high sensitivity of estrogen receptor positive (ER+) breast cancer to endocrine therapy, many patients have primary resistance or develop resistance to endocrine therapies. Acquired resist...
Adsorption and desorption of methyl orange dye on environmentally aged polyethylene, polyethylene terephthalate and polystyrene microplastics in aquatic environment
This study investigated the adsorption of methyl orange (MO), an anionic dye, on environmentally aged polyethylene (PE), polyethylene terephthalate (PET), and polystyrene (PS) microplastics (MPs) to u...
The validity of mid-upper arm circumference as an indicator of underweight, overweight and obesity adults in Bangladesh
Background Mid-upper-arm circumference (MUAC), as a simple measurement, is an effective alternative to body mass index (BMI) for resource-limited countries such as Bangladesh. The present study aimed...
Aerobic minutes and step number remain low in inpatient stroke rehabilitation
Objective Rehabilitation is important for regaining mobility poststroke. Clinical practice guidelines suggest a high number of repetitive stepping activities to optimize subacute recovery especially w...
Innovation diffusion process of higher education informatization based on Lotka-Volterra model
In order to quantify the diffusion speed, influence scope and change trend of educational informatization innovation in colleges and universities, this paper studies the diffusion process of education...
Suicide prevention curriculum development for health and social care students: A scoping review
Background Suicide is a widely recognised public health concern. International evidence indicates that many individuals who die by suicide have had contact with a healthcare professional in the year p...
A cross-sectional study of early marriage among ever-married Somali women: Prevalence, regional differences, and sociodemographic determinants
This study aims to examine the prevalence of early marriage among ever-married Somali women aged 20−49, assess differences across age groups and regions, and identify the main sociodemographic and con...
AI-driven skin cancer detection from smartphone images: A hybrid model using ViT, adaptive thresholding, black-hat transformation, and XGBoost
Skin cancer is a significant global public health issue, with millions of new cases identified each year. Recent breakthroughs in artificial intelligence, especially deep learning, possess considerabl...
Research on the generation of food safety network public opinion—Taking the Chinese Mouse Head Duck Neck Incident as an example
In recent years, the frequent occurrence of food safety incidents has posed a serious threat to people’s lives and properties, and triggered heated discussions in the whole society. If the relevant de...
Diagnostic value of long noncoding RNAs as biomarkers for Ankylosing Spondylitis: A systematic review and meta-analysis
Introduction Ankylosing spondylitis (AS) presents as a debilitating form of arthritis with potential for severe damage. In chronic cases, patients may experience progression to ankylosis and spinal im...
Assessing cancer knowledge among pharmacy students in Jordan: Bridging the gap between theory and practice
Background Early detection of cancer is essential in improving patients’ clinical outcomes. As future first-line health providers, pharmacy students must possess strong knowledge and education regardi...
Evaluation of Streptococcus pneumoniae as a cause of acute otitis media in Colombia: A prospective study
Objective Since the introduction of the pneumococcal conjugate vaccine PCV-10 in 2011 its impact on acute otitis media (AOM) in children under five years of age in Colombia was unknown. We aimed to de...
Memory improving effect of silkworm larva on insulin resistance related cognitive impairment model
Hongjam (HJ) is the steamed and freeze-dried powder of larva-stage silkworm ( Bombyx mori ) rich in protein, unsaturated fatty acids, and minerals. Silkworm pro...
Hyperparameter tuned deep learning-driven medical image analysis for intracranial hemorrhage detection
Intracranial haemorrhage (ICH) is a crucial medical emergency that entails prompt assessment and management. Compared to conventional clinical tests, the need for computerized medical assistance for p...