PLoS ONE
Articles in this Issue
Comparison of respiratory muscle activities and cardiovascular function during different breathing types in healthy adults: Costal breathing, flow incentive spirometry, and volume incentive spirometry
Background Various breathing exercises are used to enhance lung function. However, many patients have reported experiencing breathlessness and an increased work of breathing during their use, but evid...
Neural network-based identification for scallops (Pecten maximus) in natural marine habitats
The Great Atlantic scallop, or King scallop (Pecten maximus), ranks third in value after mackerel and Nephrops in UK fisheries. Its landings have surged over recent decades, making it the UK’s fastest...
Pancreatoduodenectomy versus total pancreatectomy and simultaneous intraportal islet autotransplantation for periampullary cancer at high-risk of postoperative pancreatic fistula (XANDTX-trial): Protocol of a randomized controlled pilot trial
Introduction Pancreatic surgery remains associated with significant morbidity. Pancreatoduodenectomy (PD) with high-risk stigmata for postoperative pancreatic fistula (POPF) may delay or hinder admini...
The joys and frustrations of life as an embedded researcher: Findings from a diary study of researchers embedded within local authority public health teams in England
Embedded researcher interventions endeavour to facilitate culture changes in the production and use of research, so that research is contextually relevant for informing local policies and practices. H...
Potential impacts of 2.3.4.4b highly pathogenic H5N1 avian influenza virus infection on Snow Goose (Anser caerulescens) movement ecology
While wild waterfowl are known reservoirs of avian influenza viruses and facilitate the movement of these viruses, there are notable differences in the response to infection across species. This study...
Strategies for assessing and preventing cardiovascular disease risk in inflammatory bowel disease patients: A meta-analysis and meta-regression and bibliometric review
Objective To evaluate how inflammatory bowel disease in adults increases the risk of developing cardiovascular disease. Design Meta-analysis, meta-regression and bibliometric review. Data sources...
Astaxanthin and thiamine dynamics in the copepod Temora longicornis in response to ultraviolet radiation exposure
Several aquatic top predators suffer from deficiency in vitamin B1 (thiamine), sometimes combined with low levels of carotenoid pigments, e.g., astaxanthin. The mechanisms leading to correlations betw...
In vitro and in vivo characterization of wild type BMP9 and a non-osteogenic variant in models of pulmonary arterial hypertension
Endothelial dysfunction and the resulting vascular remodeling are hallmarks of pulmonary hypertension, a debilitating disease of high arterial pressure in the lungs and the right side of the heart. Mu...
Translation, cross-cultural adaptation, validity and reliability of the inaugural Albanian Roland-Morris Disability Questionnaire in Albanian population with low back pain
Background context To precisely evaluate the disability resulting from low back pain and the efficacy of interventions, it is essential to utilize a standardized instrument capable...
Geomagnetic disturbances and grid vulnerability: Correlating storm intensity with power system failures
Geomagnetic storms represent a critical yet sometimes overlooked factor affecting the reliability of modern power systems. This study examines the relationship between geomagnetic storm activity—chara...
Socioeconomic disparities in cognitive impairment, quality of life, and mortality among older adults in Germany
Background The global older population is increasing, leading to a rise in non-communicable diseases and disabilities, particularly in Western countries. With the aging population expanding and the nu...
The Dialogue study: Protocol for a randomized clinical trial evaluating the efficacy of virtual reality-based psychotherapy plus treatment as usual versus treatment as usual for eating disorders
Background: There is considerable interest in developing novel psychological interventions for eating disorders targeting characteristics potentially serving as maintaining factors in eating disorder...
Phosphatidylcholine suppresses inflammatory responses in LPS-stimulated MG6 microglial cells by inhibiting NF-κB/JNK/p38 MAPK signaling
Phosphatidylcholine (PC), a choline-containing phospholipid abundant in chicken eggs, is widely consumed as a dietary supplement. Epidemiological studies suggest that PC intake may improve cognitive f...
Outcomes of myasthenia gravis patients admitted to the Intensive Care Unit: Experience from a tertiary care center in Saudi Arabia
Background Myasthenia gravis is an autoimmune disorder that affects the neuromuscular junction resulting in muscle weakness and fatigue. The aim of this study was to investigate the indications for an...
Predictors of gestational weight gain in western India: Findings from a longitudinal study across rural and urban cohorts
Background Gestational weight gain-GWG is an important predictor of neonatal growth. However, there is dearth of literature from rural and urban India depicting longitudinal patterns and determinants...
Frailty Assessment for Risk prediction in Gynecologic Oncology patients undergoing surgery and chemotherapy (FARGO) study protocol: Rationale and design of a multi-centre prospective cohort study
Background There is considerable variability in how older adults with cancer tolerate and recover from surgery and systemic treatments. A greater understanding of individual trajectories is crucial in...
The association between Toxoplasma gondii infection and asthma in the United States: A cross-sectional survey analysis
The hygiene hypothesis proposes that declining exposure to microbial influences early in life is implicated in the rising trend of allergy and asthma in high-income societies. Approximately 8% of Amer...
A new Maxwell model and its application in researching the compressive creep properties of recombinant bamboo
Fiber-reinforced composite materials manufactured through gluing techniques, such as recombinant bamboo, usually exhibit obvious creep behavior during service. In this work, the compressive creep perf...
Mathematical bridge between epidemiological and molecular data on cancer and beyond
Background: At least six different mathematical models of cancer and their countless variations and combinations have been published to date in the scientific literature that reaso...
Digital insights: Analyzing the reproductive intentions and influencing factors among urban women in China through online platforms
Objective To explore how fertility-related sentiments expressed by urban Chinese women varied over time and were framed in online discourse between 2011 and 2024. Methods This study employed natural...
The disease burden of gout in Asian countries and regions from 1990 to 2021, risk factors and forecast analysis: A systematic study of Asian disease burden in 2021
Objective Use the Global Burden of Disease (GBD) database to obtain gout’s disease burden indicators, risk factors, 1990–2021 data in Asian countries/regions and 2050 forecast data for gout prevention...
Single cell transcriptomic analysis reveals transcriptome differences of different cells between eosinophilic chronic rhinosinusitis with nasal polyps and non-eosinophilic chronic rhinosinusitis with nasal polyps
Background Chronic rhinosinusitis (CRS) with nasal polyps is a heterogeneous chronic inflammatory disease generally divided into two phenotypes including eosinophilic CRS with nasal polyps (eCRSwNP) a...
Does social media information affect individual investor disposition effect? Evidence from Xueqiu
The irrational behavior of investors selling profitable assets too early while holding onto losing assets for too long is known as the disposition effect. Due to the development of the Internet, the i...
Addressing biodiversity knowledge shortfalls in New World Helicopsychidae (Insecta, Trichoptera): Potential distribution, environmental gradients, and identification of conservation and research priority areas
This study provides an integrative analysis of Helicopsychidae biodiversity in the New World (NW), examining their distribution patterns, environmental gradients, biodiversity hotspots, and biodiversi...
Effects of standard and low doses of estradiol on markers of endometrial receptivity in frozen-thawed embryo transfer cycles: Double-blind, randomized clinical trial
Background Endometrial receptivity biomarkers, specifically the regulatory proteins HOXA-10 and HOXA-11 as well as the integrin αvβ3, play vital roles in implantation during the window of implantation...