PLoS ONE
Articles in this Issue
Oral creatine in hemodialysis patients increases physical functional capacity and muscle mass, an open label study
Background and hypothesis Individuals undergoing chronic hemodialysis represent a population with high morbidity and mortality, primarily due to poor nutritional status, chronic inflammation, and card...
Renal cancer survival in clear cell renal cancer compared to other types of tumor histology: A population-based cohort study
Introduction Renal cancer (RC) presents a challenge with increasing incidence and mortality. This study compares RC cancer-specific survival (CSS) and overall survival (OS) based on histological type....
The impact of demographic factors and personality traits on nurse compassion fatigue: A cross-sectional analysis
Background Compassion fatigue significantly impacts nurses’ work efficiency, care quality, and overall well-being. Consequently, the phenomenon of compassion fatigue among nurses has garnered consider...
Structure-based virtual screening, molecular docking, and MD simulation studies: An in-silico approach for identifying potential MBL inhibitors
The global rise of antibiotic-resistant infections has been driven in part by the spread of bacteria producing metallo-β-lactamase (MBL), particularly New Delhi metallo-β-lactamase-1 (NDM-1). Currentl...
PairReg: A method for enhancing the learning of molecular structure representation in equivariant graph neural networks
The 3D structure of molecules contains a wealth of important information, but traditional 3DCNN-based methods fail to adequately address the transformations of rigid motions (rotation, translation, an...
Effects of microbial-derived long-chain polyunsaturated fatty acids from Aurantiochytrium limacinum BCC52274 and Mortierella sp. on growth and immunity in Litopenaeus vannamei post-larvae
The rapid growth of the aquaculture industry has increased the demand for feed ingredients, resulting in a shortage of fishmeal and fish oil, the latter of which serves as a source of essential fatty...
Comparative evaluation of root canal morphology in mandibular first premolars with deep radicular grooves using direct vision, dental operating microscope, 2D radiographic visualisation and micro-computed tomography
Objectives The objective of this study was to evaluate the effectiveness of clinically applicable diagnostic methods such as Direct Vision (DV), Dental Operating Microscope (DOM), and two-dimensional...
Clinical and molecular characterization of hepatic glycogen storage disease in Saudi Arabia
Background and objectives The paucity of data on glycogen storage diseases (GSDs) from Arabs prompted us to report on hepatic GSD to characterize its clinical and molecular features and outcomes among...
Does an improved HDI trigger tourism outflows for China? New evidence from the ARDL cointegration approach
Extant studies have predominantly focused on understanding the effects of inbound tourism on economic growth. At the same time, it ignores the key factors that promote outbound tourism in a country. O...
Comprehensive analysis of molecular characteristic and clinical prognosis of CD8+ T cell related genes in idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a progressive, life-threatening interstitial lung disease whose pathogenesis remains unclear. There is evidence showing the possible role of CD8+ T cells in the...
An instrumented approach to quantify wrist and finger flexor spasticity: A study protocol
Spasticity in the upper limb is a common condition observed in individuals with Cerebral Palsy, post-stroke or following traumatic brain injury. Affected patients present with significant functional a...
Expression of Concern: Atm inhibition decreases lens opacity in a rat model of galactose-induced cataract
Effect of tillage system on epigeal and foliar insect predation in an organic cropping system in Pennsylvania, USA
Organic growers rely largely on cultural and biological control to manage pest populations and often use soil disturbance with inversion tillage to manage pests and weeds, incorporate crop residues an...
Synthesis, physical properties, and root canal sealing of experimental MTA- and salicylate-based root canal sealers
Objectives To develop and evaluate the physical properties and sealing ability within the root canal of three experimental sealers based on MTA and a salicylate resin. Materials and methods The expe...
Experience of clinical incivility and stress in nursing students: A mixed-method study
Nursing students often experience uncivil words or actions during clinical practice which can lead to significant stress. The purpose of our study was to quantitatively investigate the degree of clini...
Genetic diversity and evolutionary insights of Dali tea (Camellia taliensis) in the Lancang River Basin: Implications for tea breeding and resource conservation
Dali tea (Camellia taliensis), serving as a primitive wild species within the section Thea, represents a crucial genetic source for the domestication of Pu-erh tea (C. sinensis var. assamica) due to i...
Apparent differences between human and chimp proteomes are reduced when considering human population: Human specific variants are enriched in disordered and compositionally biased regions
Humans exhibit significant differences from other primates in anatomy, physiology, behavior, and culture, despite having similar genomes. Understanding the genetic basis of these unique human traits h...
Surgical workspace in porcine thoracoscopy with two-lung ventilation
In neonatal and pediatric thoracoscopy, two-lung ventilation is often used due to the size constraints of double-lumen tubes or selective bronchial blockers. Reducing the volume of both lungs to creat...
Iterative learning control of neuronal firing based on FHN and HR models
Neuronal firing patterns are fundamental to neural information processing and functional regulation, with abnormal firing closely linked to a range of neurological disorders. However, existing neuromo...
Evaluating the short-term effects of dance on motor and non-motor outcomes in people living with Parkinson’s: A crossover study
Purpose To investigate the short-term effects of a single dance class on motor and non-motor outcomes in people living with Parkinson’s. Methods A crossover design was used. Nineteen people particip...
Estimation of free-roaming dog populations using Google Street View: A methodological study
Controlling and eliminating zoonotic pathogens such as rabies virus, Echinococcus granulosus, and Leishmania spp. require quantitative knowledge of dog populations. Dog population estimates are fundam...
Care mobilities and associated contexts of hospital-based informal caregiving in Nigeria: Towards an explanatory framework
Hospital-based informal caregiving in Nigeria is shaped by care mobilities and contextual factors such as policy contradictions and normative care philosophies. This study explores how these factors i...
Spinal needles versus conventional needles for fine-needle aspiration biopsy of thyroid nodules—A multicenter randomized controlled trial
Objective Ultrasound-guided fine-needle aspiration biopsy (FNAB) is essential for evaluating thyroid nodules but often yields inadequate samples, leading to repeated procedures, increased discomfort,...
A long-term localization and mapping system for autonomous inspection robots in large-scale environments using 3D LiDAR sensors
Inspection mobile robots equipped with 3D LiDAR sensors are now widely used in substations and other critical circumstances. However, the application of traditional LiDAR sensors is restricted in larg...
Optimal Anisotropic Guided Filtering in retinal fundus imaging: A dual approach to enhancement and segmentation
Retinal vascular tree segmentation and enhancement has significant medical imaging benefits because, unlike any other human organ, the retina allows non-invasive observation of blood microcirculation,...