PLoS ONE
Articles in this Issue
Mechanisms responsible for the ability of enoxaparin sodium to inhibit inflammatory responses in the immune microenvironment of bone repair: A transcriptomic sequencing study
Enoxaparin sodium (ES), a low molecular weight heparin derivative, has recently been recognized for its diverse biological activities. In particular, the ability of heparin to modulate inflammation ha...
Comparative biocompatibility of hydrophilic vs. hydrophobic intraocular lenses following phacoemulsification in patients with uveitis
Purpose To evaluate and compare the biocompatibility of hydrophilic and hydrophobic intraocular lenses (IOLs) in patients with uveitis undergoing phacoemulsification, with particular focus on posterio...
Information sharing and channel structure in e-commerce supply chain considering data-driven marketing
E-tailers such as Amazon and Tmall can accurately recognize consumer interest in product categories and grasp current consumer trends through product recommendation algorithms and data-driven analysis...
A prospective, multicenter study of invasive fungal disease caused by molds in children and adults in Chile
Background Invasive mold diseases (IMDs) are a severe complication of immunocompromised subjects and an emerging problem among severely ill, apparently immunocompetent patients. The aim of this study...
Assessing mosquito dynamics and dengue transmission in Foz do Iguaçu, Brazil through an enhanced temperature-dependent mathematical model
Dengue fever remains a major public health concern, requiring continuous efforts to mitigate its impact. This study investigates the influence of key temperature-dependent parameters on dengue transmi...
Machine learning-based prediction model for 28-day mortality in acute kidney injury patients with liver cirrhosis: A MIMIC-IV database analysis
Background Acute kidney injury (AKI) in patients with liver cirrhosis represents a significant clinical challenge with high mortality rates. This study aimed to develop and validate a machine learning...
Dual-band mixed-mode bandpass filter based on dual-layer substrate integrated waveguide resonator loaded with A capacitive patch
To address the growing demand for compact and high-performance microwave filters in modern communication systems, a mixed-mode bandpass filter is proposed in the article. A dual-layer substrate integr...
Analysis of the characteristics of geography study tour program development in China
Using 730 winning entries in the 2023 “Kyushu Cup” National Study Tour Program Design Competition as examples, this article analyzes characteristics of geography study tour program development in Chin...
Suicide rates in Germany in lockdown and non-lockdown phases during the COVID-19 pandemic in 2020/2021
Contrary to the cautions of many, suicide rates during the first COVID-19 pandemic lockdown in Germany did not rise, but declined. With the accessibility of the 2021 weekly suicide data, it was possib...
Digital health technologies in Primary Health Care in rural territories: A protocol for scoping review
Aim To describe the protocol for a scoping review on digital health technologies in Primary Health Care in rural territories, with a view to evaluating their impact on the attributes of Primary Health...
AI-Driven quality assurance in mammography: Enhancing quality control efficiency through automated phantom image evaluation in South Korea
Purpose To develop and validate a deep learning-based model for automated evaluation of mammography phantom images, with the goal of improving inter-radiologist agreement and enhancing the efficiency...
The impact of fires on mosquito populations in Eastern Siberian forests
Forest fires have a significant impact on forest fauna, killing not only mammals and birds, but also less noticeable representatives of forest fauna – insects. Existing research have mainly studied th...
Healthcare providers’ knowledge on sickle cell disease and its management: A pre- and post-training test evaluation outcome
In resource-limited settings in Africa, which harbour the greatest burden of Sickle Cell Disease (SCD) globally, poor care outcomes are driven in part, by a lack of trained healthcare providers (HCP)...
Fostering culture of care for early career researchers—Building a trustful environment: Insights from a German perspective
Early-career researchers (ECRs) play a key role in conducting animal experiments in academic research. However, they face considerable challenges, including poor working conditions, and inadequate str...
Sex as a moderator of the relationship between hip abduction strength and muscle activation during single-leg stance
Background Single-leg stance requires pelvic stability, largely supported by the hip abductors. Differences in hip abductor activation between sexes and individuals with or without musculoskeletal con...
Resting vagal tone, alpha amylase and cortisol levels in women with eating disorders before and after psychotherapy
Background Eating disorders such as Anorexia Nervosa (AN) and Bulimia Nervosa (BN) were previously found to partly entail alterations in stress physiology including salivary cortisol (sC), and salivar...
Reducing emergency department length of stay for hematology patients of tikur anbessa specialized hospital: An improvement initiative
Introduction Prolonged Emergency Department (ED) stays, a global issue driving overcrowding, were exacerbated at our hospital by lab delays and extended waits, increasing patient stress. This study ai...
Causal associations between psoriasis and atopic dermatitis: A bidirectional Mendelian randomization study
Background Although previous studies suggested associations between psoriasis and atopic dermatitis (AD), the directionality and causality of these relationships remain controversial. This study emplo...
Targeting the Exon2 splice cis-element in PD-1 and its effects on lymphocyte function
T-cell therapies have proven to be a promising treatment option for cancer patients in recent years, especially in the case of chimeric antigen receptor (CAR)-T cell therapy. However, the therapy is a...
Correction: The effects of probabilistic context inference on motor adaptation
Biomechanical characteristics of swing techniques using different clubs in college male golfers
Background Golf is a sophisticated sport that integrates precision, skillfulness, and strategic thinking, with swing techniques of different clubs exhibiting distinct biomechanical characteristics. Th...
Propofol emulsification in Intralipid and SMOFlipid: A promising alternative in response to future shortages
Introduction The Covid-19 pandemic has intensified shortages in various pharmaceutical products, notably injectable propofol in lipid emulsion form. Its demand surged sharply due to its critical role...
Short-term costs and cost-efficiency of HPV triage strategies in a high HIV-prevalence setting: Evidence from Botswana
Cervical cancer remains the leading cause of cancer death among women in sub-Saharan Africa and is more severe in high HIV-burdened countries due to persistent high-risk human papillomavirus (hrHPV)....
Evaluation of mechanical ventilation modes in the laparoscopic perioperative period with electrical impedance tomography
Purpose Uncertainty persists regarding the optimal mode of mechanical ventilation for laparoscopic perioperative periods. Electrical impedance tomography (EIT) is an effective tool for monitoring and...
Drug-induced vitiligo: a real-world pharmacovigilance analysis of the FAERS database
Background In recent years, with the expanding use of novel therapeutics such as immune checkpoint inhibitors and monoclonal antibodies, reports of drug-induced vitiligo have been increasing. This stu...