PLoS ONE
Articles in this Issue
Behavioural analysis of multi-year satellite telemetry data provides insight into narwhal (Monodon monoceros) winter prey selection in Baffin Bay
Narwhals (Monodon monoceros) are deep-diving Arctic cetaceans that migrate seasonally between summering and wintering grounds. The Baffin Bay population overwinters in southern Baffin Bay and Davis St...
Association between hemoglobin glycation index and 28-day all-cause mortality in acute myocardial infarction patients: Analysis of the MIMIC-IV database
Acute myocardial infarction (AMI) substantially fuels the worldwide escalation in both morbidity and mortality. The hemoglobin glycation index (HGI) is linked to a range of undesirable outcomes, but i...
Antimalarial and neuroprotective effects of ethanolic extracts of the five-flower remedy in an experimental cerebral malaria model
Cerebral malaria (CM), a life-threatening consequence of Plasmodium falciparum infection, is associated with a high fatality rate and long-term brain impairment in survivors. Despite advances in malar...
Evaluation of flow control using PID versus fuzzy logic in an electropneumatic circuit for pulmonary ventilation applications
High-tech mechanical ventilators are engineered to deliver precise and consistent airflow, which is critical for effective respiratory therapy. This study evaluates flow control performance in a custo...
Expression of Concern: ChainAgile: A framework for the improvement of Scrum Agile distributed software development based on blockchain
Deep momentum networks with market trend dynamics
Time-series momentum (TSMOM) trading strategies manage positions based on the persistence of return trends. Although long short-term memory (LSTM) deep neural architectures can enhance TSMOM, their pe...
Epidemiological trends and projections to 2035 of hepatitis B burden in China, 1990–2021
Background Hepatitis B virus (HBV) remains a major cause of liver disease and premature death globally, with China bearing a significant share of the burden. However, long-term trends and future proje...
Associations of self-reported hearing problems with long-term trajectories of mental and functional health in middle-aged and older adults: The role of self-perceptions of aging
Impaired hearing is a frequent stressful experience in later life. However, not all individuals affected by hearing problems exhibit restrictions in mental or functional health; there may be psychosoc...
The perception of individuals with low back pain regarding reassuring information: Insights based on physiotherapists messages
Background Clinical guidelines for the management of low back pain (LBP) emphasize the importance of reassuring patients, as this reduces concern and increases confidence in recove...
Phytochemical and pharmacoinformatics analysis of a traditional antipsoriatic oil formulation for its potential against proinflammatory cytokines TNF-α and IL-17A
Psoriasis, a persistent inflammatory condition with a complex origin, lacks a definitive cure despite the availability of diverse treatments. Vetpalai thailam (VT), a Siddha formulation, is commonly u...
Enhancing glioma immunohistochemical image classification through color deconvolution-aware prior guidance
Glioma diagnosis and prognosis heavily rely on immunohistochemistry (IHC), particularly CD34-stained images which highlight tumor vascular endothelial cells. However, traditional image analysis method...
Retraction: Maintenance of Stemness in Oxaliplatin-Resistant Hepatocellular Carcinoma Is Associated with Increased Autocrine of IGF1
The second survey of the Saudi Acute Myocardial Infarction Registry Program: Main results and temporal changes in care (STARS-2 program)
Background The Saudi Acute Myocardial Infarction Registry (STARS) program aims to evaluate the clinical characteristics, management, and outcomes of a representative sample of patients with acute myoc...
AA-Amyloidosis in the Eurasian stone-curlew (Burhinus oedicnemus)
Amyloidosis is a group of protein misfolding diseases and a well-recognized disorder in avian species. However, the knowledge of wild avian amyloid proteome is scarce. We report here gross, histopatho...
An intelligent diagnosis method for cardiovascular diseases based on the CNN-CBAM-GRU model
Early diagnosis of cardiovascular diseases (CVDs) is essential for improving patient outcomes. As a primary diagnostic modality, electrocardiogram (ECG) signals pose challenges for automatic classific...
Assessing the potential of seaweed extracts to improve vegetative, physiological and berry quality parameters in Vitis vinifera cv. Chardonnay under cool climatic conditions
Seaweed extracts are promising plant biostimulants for viticulture, but their effects on white winegrape cultivars grown under cool climates remain fairly undocumented. Furthermore, information is lim...
Charantin targets HMGCR-PCSK9 axis and activates PPAR-α signaling to ameliorate hyperlipidemia: Mechanistic insights from bioinformatics and in-vivo studies
Plant-derived compounds have recently gained attention owing to their better safety profile and multi-targeted actions. Charantin, a plant-based natural compound known for its diverse pharmacological...
Willingness to use long-acting injectable pre-exposure prophylaxis (LAI-PrEP) among black cisgender women in the Southern United States
Background Long-acting injectable pre-exposure prophylaxis (LAI-PrEP) for HIV prevention may improve adherence for those with concerns with daily pills. Limited data exist on LAI-PrEP acceptability am...
Ethical implications of neurotechnology in industry-academia partnerships: Insights from patient and research participant interviews
Background Neurotechnologies often advance through industry-academia (IA) partnerships and offer insight into brain and nervous system functions, bringing improved diagnosis and treatment options to p...
Psychometric evaluation of the Persian nursing students’ learning self-efficacy instrument
The preparedness of the nursing workforce is a critical determinant of patient safety and healthcare quality, with academic performance serving as a key contributor to this preparedness. Self-efficacy...
Analysis of global, regional, and national burden and attributable risk factors of acute lymphoblastic leukemia and acute myeloid leukemia from 1990 to 2021
Background Acute Leukemia (AL) is a prevalent subtype of leukemia, mainly including acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). The disease burden of acute leukemia has signif...
A machine learning approach for detecting WPA3 downgrade attacks in next-generation Wi-Fi systems
This paper presents a hybrid adaptive approach based on machine learning (ML) for classifying incoming traffic, feature selection and thresholding, aimed at enhancing downgrade attack detection in Wi-...
Cyclic assisted cloning of arbitrary unknown single-particle states in amplitude damping channel
In this paper, two conclusive three-party cyclic assisted cloning protocols in amplitude damping (AD) channel are put forward that, respectively clone three arbitrary unknown single-qubit states and s...
Defining metabolic abnormalities in acute human traumatic brain injury with cerebral microdialysis and multimodality monitoring
Objective We aimed to compare the prevalence and multimodal associations of mitochondrial dysfunction as defined by published cerebral-microdialysis-based criteria versus our novel multimodality-monit...
Improving adherence to physical activity in treatment-resistant depression: Protocol for a pilot randomized controlled trial of a remotely delivered program
Background At least 30% of individuals with major depressive disorder do not respond to conventional treatments (i.e., they meet the criteria for treatment-resistant depression [TRD]). Alternative the...