PLoS ONE
Articles in this Issue
The wrapping Epanechnikov exponential distribution: A novel flexible model for asymmetric circular data
This study introduces the Wrapped Epanechnikov Exponential Distribution (WEED), a novel circular distribution derived from the Epanechnikov exponential distribution. The probability density function a...
Psychosocial predictors of mobbing and burnout in para-athletes: Insights for mental health
Para-athletes may experience psychological challenges such as mobbing and burnout, which can impair their performance, motivation, and well-being. Despite the inclusive goals of the Paralympic Movemen...
Cohort profile: The Multiethnic Lifestyle, Obesity and Diabetes Registry in Malaysia (MeLODY) retrospective cohort in a middle-income country in Southeast Asia
There is a lack of longitudinal data on type 2 diabetes (T2D) in low- and middle-income countries. We leveraged the electronic health records (EHR) system of a publicly funded academic institution to...
AHL-based QS signalling promotes uropathogenic Escherichia coli settlement through the de-repression of biofilm formation by SdiA
Uropathogenic Escherichia coli (UPEC) are among the first pathogens to colonise in catheter and non-catheter-associated urinary tract infections. However, these infections are often polymicrobial, res...
ICTUSCOG: Poststroke cognitive impairment following nondisabling stroke: Study protocol of a spanish multicentre prospective cohort study
Background Stroke is a leading cause of death and disability globally, with frequent cognitive sequelae affecting up to 60% of stroke survivors. Despite the high prevalence of post-stroke cognitive im...
Efficacy and mechanism of high-purity HAMCC combined with CGF in promoting the repair of radiation-induced skin and soft tissue damage
Radiotherapy, a prevalent and effective treatment for various malignancies, often causes collateral damage to normal skin and soft tissues in the irradiated area. To address this, we developed a novel...
Microbial quality assessment of Niger seed (Guizotia abyssinica (Linnaeus f.) Cassini) oil in Gondar city: A laboratory-based cross-sectional study
Foodborne diseases pose a significant public health challenge worldwide. The increasing availability of edible oils in the market, combined with Ethiopia’s lack of stringent quality control and regula...
Scenario simulation analysis of urbanization spatial pattern optimization promoting regional coordinated development: A case study of Guizhou, China
This research delves into the optimization of urbanization spatial patterns in Guizhou Province, China. The findings reveal that with regional coordinated development as the central objective and the...
Evaluation of diagnostic measurements in patients with non-specific complaints: A secondary analysis after implementation of a care-pathway in the emergency department
Background Older patients presenting with nonspecific complaints (NSC) in the Emergency Department (ED) pose diagnostic challenges. The lack of clear symptoms leads to high misdiagnosis rates, extende...
Prevalence and predictors of viral load non-suppression among adolescents on dolutegravir-based antiretroviral therapy: A cross-sectional study from three urban clinics, Soroti City
Background Despite advances in HIV care, viral load suppression (VLS) among adolescents living with HIV (ALHIV) in Uganda continue to lag behind that of adults, even with the introduction of dolutegra...
Nutritional supplement containing a nuclear fraction of bovine thymus gland increases the circulating levels of spermidine
Polyamines (PAs), including spermidine, spermine and their precursor, putrescine, are ubiquitous molecules that are vital for a variety of physiological processes. Recently, PAs gained research attent...
Social-ecological goals and outcomes of public engagement for recovery of endangered and threatened rockfishes (Sebastes spp.)
Natural resource management agencies commonly conduct outreach and engagement with the public, with the goals of raising awareness, educating constituents, encouraging compliance with rules, and suppo...
Medication multiple experiences of elderly patient with multiple chronic condition: A qualitative meta-synthesis
Purpose To determine the experience of medication multiple in elderly patients with multiple chronic condition by systematically reviewing, retrieving, and synthesizing data from qualitative studies....
Exploration of the social determinants of diarrhoea, rotavirus vaccine uptake, and vaccine ‘fatigue’ in Ethiopia, Kenya, and Malawi
Diarrhoea due to rotavirus remains a significant cause of child mortality in developing regions. Caregivers’ perspectives on the social determinants of gastroenteritis and childhood vaccination, inclu...
The experience of cerebral palsy stigma amongst adults living in the UK and Ireland: A qualitative co-designed project
Background There is evidence that cerebral palsy (CP) could be linked to stigma and discrimination, however current evidence is limited to small qualitative studies. The goal of this co-designed surve...
The flavonoid rutin protects against imidacloprid-induced osmotic and electric disruptions in Africanized honey bees
Honey bees (Apis mellifera) are essential pollinators threatened by sublethal effects of pesticides such as imidacloprid, a widely used neonicotinoid that disrupts the central nervous system. However,...
Development efficiency of green logistics in Guangdong province based on Super-SBM and GML index
Under China’s national sustainability strategy, the logistics industry is confronted with the imperative of high-quality green development. Given its status as the leading economic province and a nati...
Impact of digital technology on herders’ grassland leasing-in decisions in Inner Mongolia, China
Against the backdrop of grassland ecological degradation, grassland transfer has become a crucial pathway for optimizing livestock resource allocation and promoting sustainable pastoral development. B...
Minoritized students and their faculty research mentors view benevolence differently in the relationship
There are many benefits for students who participate in undergraduate research experiences, including increased retention and persistence in science, technology, engineering, and mathematics (STEM). B...
Cultural heritage of the Qin-Shu Ancient Road in Shaanxi: Spatial distribution characteristics and influencing factors
This study investigates the spatial and temporal distribution and the influencing factors of 579 cultural heritage sites along the Qin–Shu Ancient Road in Shaanxi Province, employing kernel density es...
Assessment of industrial fault diagnosis using rough approximations of fuzzy hypersoft sets
Reliable and timely fault diagnosis is critical for the safe and efficient operation of industrial systems. However, conventional diagnostic methods often struggle to handle uncertainties, vague data,...
Investigating the optimal reactive balance training intensity in people with chronic stroke: Study protocol for a randomized control trial
Stroke significantly contributes to long-term disability, one of the problems is with impaired balance control, increasing the risk of falls. The risk of falls may be mitigated using reactive balance...
Navigating Hepatitis C care: Knowledge gaps and access barriers among young women who inject drugs in rural Appalachia
Background Hepatitis C virus (HCV) and injection drug use among young women are dramatically rising in the rural United States. From 2004 to 2017, heroin use among non-pregnant women increased 22.4% b...
Kidney stone disease increases the risk of cardiovascular events
Introduction Kidney stone disease is associated with numerous cardiovascular risk factors. However, the findings across studies are non-uniformly consistent, and the control of confounding variables r...
Factors associated with prolonged hospitalizations for COVID-19 during the first three waves of the pandemic: Evidence from a Southeastern State of Brazil
A comprehensive understanding of the factors influencing the epidemiological dynamics of COVID-19 across the pandemic waves—particularly in terms of disease severity and mortality—is critical for opti...