PLoS ONE
Articles in this Issue
Exploring the limits of exercise capacity in adults with type II diabetes
Objective This study investigates the mechanisms behind exercise capacity in adults with type 2 diabetes mellitus (T2DM), focusing on central and peripheral components, as described by the Fick equati...
CaOx crystal nuclei are formed in rat outer cortex proximal tubules by a potential fibrinogen-dependent mechanism
Calcium oxalate (CaOx) stones are prevalent in urinary tract stone disease. While their formation can be induced in rats by administering ethylene glycol and vitamin D, the initial nucleation and form...
Understanding financial hardship in families of people living with dementia: Protocol for a scoping review to identify subjective self-report measures that evaluate financial hardship
Background Financial hardship (including financial stress, financial strain, asset depletion, and financial toxicity) is a highly relevant construct among the 6.9 million people living with Alzheimer’...
Synergistic antibacterial action of AgNP-ampicillin conjugates: Evading β-lactamase degradation in ampicillin-resistant clinical isolates
Objectives Antibiotic resistance towards penicillin has been attempted to counter by chemically modifying ampicillin through the conjugation with silver nanoparticles (AgNPs). The current study optimi...
Long sequence temporal knowledge tracing for student performance prediction via integrating LSTM and informer
Knowledge tracing can reveal students’ level of knowledge in relation to their learning performance. Recently, plenty of machine learning algorithms have been proposed to exploit to implement knowledg...
Characteristics of a tattooed population and a possible role of tattoos as a risk factor for chronic diseases: Results from the LIFE-Adult-Study
Tattoos and permanent make-up (PMU) gain increasing popularity among the general population. There are indications that pigments or their fragments may translocate within the body, however knowledge a...
Evaluating antibody mediated opsonophagocytosis of bacteria via lab protocol: RAW 264.7 cell phagocytosis assay
Assessing the phagocytosis of microbes by macrophages is an important component of studies of novel immunotherapeutics, antimicrobial drugs, immune effectors, or any immunology related research. Here...
Lead yourself to the zone and be happy: The effect of self-leadership development on flow and happiness
Background Self-leadership has been associated with several positive organizational outcomes (e.g., performance and innovation). Yet, individual subjective well-being constructs have seldom been explo...
KG-MACNF: A nonlinear cross-modal fusion model for predicting drug-target interactions via multi-relational embedding and fine-grained structure
Drug-target interaction (DTI) prediction is essential for the development of novel drugs and the repurposing of existing ones. However, when the features of drug and target are applied to biological n...
DXA-derived visceral adipose tissue reference values and metabolic syndrome risk threshold in an Algerian adult population
Background Visceral adipose tissue (VAT) is associated with several cardiometabolic risk factors, particularly metabolic syndrome and insulin resistance. Reference values for VAT vary across populatio...
Prediction of modal parameters for thin-walled blade milling process considering material removal effect
Accurate prediction of time-varying dynamic parameters during the milling process is a prerequisite for chatter-free cutting of thin-walled parts. In this paper, a matrix iterative prediction method b...
A nonlinear decomposition analysis of the rural-urban disparities in tobacco use among women in sub-Saharan Africa
Background Tobacco use remains a major public health challenge in sub-Saharan Africa, with significant gendered dimensions. Place of residence is an important determinant, as rural and urban contexts...
Smart load balancing in cloud computing: Integrating feature selection with advanced deep learning models
The increasing dependence on cloud computing as a cornerstone of modern technological infrastructures has introduced significant challenges in resource management. Traditional load-balancing technique...
How data assets influence enterprise persistent innovation: Evidence from China
This study investigates the impact of data assets on enterprise persistent innovation using panel data from Chinese A-share listed firms from 2011 to 2022. The results indicate that data assets signif...
Lie symmetry approach to the dynamical behavior and conservation laws of actin filament electrical models
This research explores the dynamical properties and solutions of actin filaments, which serve as electrical conduits for ion transport along their lengths. Utilizing the Lie symmetry approach, we iden...
Competency of triage nurse in the emergency department: A scoping review protocol
Introduction Triage is an essential strategy to mitigate crowding and guarantee patients’ safety in emergency departments. To improve the quality of triage in emergency departments, Nurses should be e...
Integrative network toxicology and molecular docking reveal 4-Nonylphenol’s multifaceted mechanisms in breast cancer pathogenesis
Objective This study employs integrated network toxicology and molecular docking to investigate the molecular basis underlying 4-nonylphenol (4-NP)-mediated enhancement of breast cancer susceptibility...
Optimizing international trade: Strategies for retaining or taking over transport remit in Poland’s import and export landscape—A case study of Company X
This study explores the economic implications of transport remit management in Poland’s international trade landscape, with a particular focus on the operations of a medium-sized Polish forwarding com...
Validation of the German Emotional Contagion Scale and development of a mimicry brief version
The susceptibility to emotional contagion has been psychometrically addressed by the self-reported Emotional Contagion Scale. With the present research, we validated a German adaptation of this scale...
American black bear (Ursus americanus) as a potential host for Campylobacter jejuni
The Gram-negative bacterium Campylobacter jejuni is part of the commensal gut microbiota of numerous animal species...
Do chimpanzees (Pan troglodytes) attribute preferences to virtual competitors?
Many animal species live in multi-level societies regulated by complex patterns of dominance. Avoiding competition with dominant group-mates for resources such as food and mates is an important skill...
1p-Enh-regulated CYP4B1 alleviates NNK-induced heart failure and lung cancer via the STAT3 pathway
Heart failure (HF) and lung cancer (LC) often coexist, yet their shared molecular mechanisms are unclear. We analyzed transcriptome data from the NCBI Gene Expression Omnibus (GEO) database (GSE141910...
Predictors of health care utilization in patients with post-acute sequelae of COVID-19 (PASC)
Background Research on Post-acute sequelae of COVID (PASC) has focused on the prevalence of symptoms, leaving gaps in our understanding of predictors of health care seeking. Objective To identify cl...
Construct prediction models for low muscle mass with metabolic syndrome using machine learning
Background Metabolic syndrome (MetS) and sarcopenia are major global public health problems, and their coexistence significantly increases the risk of death. In recent years, this trend has become inc...
Shaping resilient flood control system design through net present value assessments
Designing sustainable Flood Control Systems (FCSs) requires considering both the resiliency of the system and the long-term viability of investments. In this regard, our research aimed at integrating...