PLoS ONE
Articles in this Issue
Predicting mortality dynamics in cancer patients: A machine learning approach to pre-death events
Capturing the dynamic changes in patients’ internal states as they approach death due to fatal diseases remains a major challenge in understanding individual pathologies and improving end-of-life care...
Gaps in immunization coverage at school entry and after two years of school attendance among immigrant and refugee children in Ontario, Canada
Background Foreign-born children may face greater barriers to accessing routine immunizations in Canada or their country of birth, but provincial surveillance data on immigration status are lacking. U...
Influence of cold atmospheric pressure plasma treatment on germination and plant biomass of Trifolium pratense L.
Treatment of seeds with cold atmospheric pressure plasma (CAPP) is in its proof-of-concept phase with regard to its effect on germination and plant growth. To increase the germination of hardseeded re...
An agent-based model to advance the science of collaborative learning health systems
Improving the healthcare system is a persistent and pressing challenge. Collaborative Learning Health Systems, or Learning Health Networks (LHNs), are a novel, replicable organizational form in health...
Momentum, volume and investor sentiment study for u.s. technology sector stocks—A hidden markov model based principal component analysis
In this paper, we study the impact of momentum, volume and investor sentiment on U.S. tech sector stock returns using Principal Component Analysis-Hidden Markov Model (PCA-HMM) methodology. Price and...
Exploring the interplay between circadian rhythms and obesity: A Boolean network approach to understanding metabolic dysregulation
This study investigates the interaction between circadian rhythms and lipid metabolism disruptions in the context of obesity. Obesity is known to interfere with daily rhythmicity, a crucial process fo...
Physicochemical, microbiological, and microstructural changes in germinated wheat grain
This study investigates the physicochemical, microbiological, and microstructural changes in soft wheat grain during germination under varying moisture conditions: moderately dry, moist, and wet. Pre-...
Correction: Characteristics of the effects of Polygonati Rhizoma on gut microbiota and metabolites in vitro associated with poor dietary habits in pregnant women
Unprecedented 2020 coral bleaching reveals unexpected taxa-specific responses in the central Red Sea
Sea surface temperature of the Red Sea has increased by up to 0.45 °C per decade over the last 30 years, and coral bleaching events are becoming more frequent. A reef bleaching event was observed in O...
Enhancing fake news detection with transformer-based deep learning: A multidisciplinary approach
The widespread dissemination of fake news presents a critical challenge to the integrity of digital information and erodes public trust. This urgent problem necessitates the development of sophisticat...
Young women’s experience of personal recovery following acute myocardial infarction: A qualitative study
Background Rates of acute myocardial infarction (AMI) morbidity and mortality have increased in young women aged ≤55 years but little is known about their experience recovering from and living with AM...
Spatiotemporal disparities and dynamic transition characteristics of China’s national standard development contribution levels—Based on machine splitting and location assignment technology
This study examines China’s national standard development from 2001 to 2023. Using machine splitting and location assignment technology, the Dagum Gini coefficient and its decomposition methods, and t...
Catchment prioritization for freshwater mussel conservation in the Northeastern United States based on distribution modelling
Freshwater mussels are critical to the health of freshwater systems, but their populations are declining dramatically throughout the world. The limited resources available for freshwater mussel conser...
Intracellular lymphocyte protein biomarkers for early radiological triage in the human population
In the event of a large-scale radiological or nuclear emergency, a rapid, high-throughput screening tool will be essential for efficient triage of potentially exposed individuals, optimizing scarce me...
Prevalence and factors influencing drug-resistant tuberculosis in four regions of Ghana
Introduction The alarming rate of drug-resistant tuberculosis (DR-TB) globally is a threat to treatment success among positive tuberculosis (TB) cases. Studies aimed at determining the prevalence, tre...
Kinship verification via correlation calculation-based multi-task learning
Previous studies have demonstrated that metric learning approaches yield remarkable performance in the field of kinship verification. Nevertheless, a prevalent limitation of most existing methods lies...
Towards a definition of an existential approach in cancer patients: a co-produced scoping review
Background Attention to existential needs has become part of daily treatment. Studies have described the concepts of existential experiences and existential interventions. However, a consensus or conc...
Predictors of sexual satisfaction among Social Security and National Insurance Trust pensioners in the Greater Accra Region of Ghana
The population of pensioners remains on the rise in Ghana coupled with an intrinsic need for sexual activity and satisfaction. However, data on factors associated with sexual satisfaction among pensio...
Age does not improve the predictive ability of the Hospital Frailty Risk Score for length of stay
Background The Hospital Frailty Risk Score (HFRS) has been widely used to identify patients at high risk of poor outcomes and to predict poor outcomes for older people. Although poor health outcomes a...
The SURVIVE study (NCT05658172): Bringing breast cancer aftercare to the 21stcentury: Study protocol of a Phase III clinical trial comparing liquid biopsy guided vs. Standard of care surveillance for intermediate to high-risk breast cancer survivors
Background Current aftercare in breast cancer survivors aims to detect local recurrences or contralateral disease, while the detection of distant metastases has not been a central focus due to a lack...
A volumetric modulated arc therapy-based dynamic conformal arc technique with limited monitor units (VMATliMU) to reduce multileaf collimator interplay effects: A computational phantom study for stage I non-small-cell lung cancer
Volumetric modulated arc therapy (VMAT) for lung cancer involves complex multileaf collimator (MLC) motion, which increases sensitivity to interplay effects with tumour motion. Current dynamic conform...
Comprehensive analysis of disulfidptosis-related genes in pulmonary hypertension through machine learning and immune infiltration: Spotlight on USP32 and ZNF655 as key regulators
Background Disulfidptosis, a novel cellular death manner, has yet to be fully explored within the context of pulmonary arterial hypertension (PAH). This study aims to identify genes implicated in PAH...
Tuneable multidirectional mechanical attributes of novel sectionally nonlinearly functionally graded femur and cranial bone implants with triply periodic minimal surfaces
Sectionally nonlinearly functionally graded (SNFG) structures with triply periodic minimal surface (TPMS) are considered ideal for bone implants because they closely replicate the hierarchical, anisot...
Interprofessional education: A recognized necessity, a persistent challenge - Perspectives from a longitudinal study
Background Interprofessional Education (IPE) is widely recognized as essential for fostering collaborative healthcare practices and improving patient outcomes. Despite its acknowledged importance, the...
No evidence for increased habitual or decreased goal-directed action control after acute stress
Previous studies suggested that acute stress can impair flexible goal-directed action control in favor of habitual action control. In addition, there is evidence that acute stress differentially affec...