PLoS ONE
Articles in this Issue
Comparison of multivariable methods for determining cutpoints of biomarkers in the context of survival time analyses: A simulation study with practical applications to survival data
Introduction Survival time models are commonly employed in medicine and health sciences when analysing data. In these time-to-event analyses, it is often necessary to dichotomise v...
Existential aspects of fatherhood transition—A systematic qualitative review protocol using framework synthesis
Background Research on the experiences of parenthood transition has previously primarily focused on the mother/birthing woman. Even with an expanding interest in the existential as...
Impact of pregabalin reclassification as a controlled substance in Egypt on gabapentinoid and opioid utilization: A repeated cross-sectional study
Background Pregabalin is commonly used for treating pain but is also recognized for its misuse potential. In response to rising abuse, Egyptian health authorities reclassified preg...
Socioeconomic inequalities in overweight and obesity among adults: Results from the Indonesian Food Barometer study
Background Globally, overweight and obesity (OAO) are significant health concerns that have detrimental effects throughout an individual’s lifetime. This study examined socioeconom...
Red blood cell to platelet ratio and its trajectory as prognostic factors for patients with gastrointestinal tract perforation and abdominal sepsis
Background Sepsis after emergency gastrointestinal perforation surgery increases costs and hospital stay. Early diagnosis and management are vital. This study assesses the prognost...
A method for considering road curvature’s impact on aggressive turning
Addressing the current issue of not considering the influence of road geometry in the recognition of aggressive turning, a dangerous driving behavior, this paper proposes a method to eliminate the imp...
The flow experience: Polish adaptation and validation of the psychological flow scale (PFS)
Flow is an absorbing, effortless, and intrinsically rewarding state that unfolds over time. We adapted the nine-item Psychological Flow Scale (PFS) to Polish and evaluated it in a preregistered labora...
Potential distribution of Aedes vittatus as an invasive species in North America
The recent detection of populations of the mosquito Aedes vittatus in the Dominican Republic and Cuba has raised concerns over its potential for broader invasio...
The influence of type 2 diabetes and its metabolic correlates in middle-aged adults on cognition at mid and later life; A systematic review and meta-analysis
Introduction While previous studies have examined the link between Type 2 Diabetes Mellitus (T2DM) and cognitive function in middle-aged adults, no review has explored the long-ter...
Adeno-associated vector corneal gene therapy reverses corneal clouding in a feline model of mucopolysaccharidosis VI
Mucopolysaccharidosis VI (MPS VI) is a rare, autosomal recessive lysosomal storage disease caused by mutations in the arylsulfatase B gene ( ARSB ). Ocular mani...
Influencing factors and optimization paths of teachers’ fulfillment of school bullying governance responsibilities in China
The effective fulfillment of teachers’ responsibilities is crucial to the governance of school bullying. Guided by Grounded Theory and utilizing NVivo11 qualitative analysis software, this paper used...
Conditional deletion of Tmem63b does not impact mouse voiding behavior
The proper function of the lower urinary tract depends on its ability to sense and react to mechanical forces as urine is produced, transported, stored, and eliminated; however, our current understand...
Comparative effects of French Contrast Method vs. Complex Training on explosive power and its endurance in youth badminton athletes
Badminton players normally prioritize technical and tactical training over physical conditioning before competition, presenting a challenge in enhancing physical fitness within a constrained timeframe...
Lime-based supplement reduces calcium oxalate stone recurrence: A multicenter randomized controlled trial
Background Recurrent urolithiasis is a major clinical challenge, with more than 50% of patients experiencing recurrence within 5 years. While potassium citrate effectively reduces...
Political participation and grassroots governance: A social work perspective based on CGSS 2021 data
This study, based on the 2021 China General Social Survey (CGSS), examines how different forms of political participation–spanning behavior, attitude, and affiliation –shape perceptions of grassroots...
Assessing the impact of chemo-mechanical and soxhlet extraction techniques on cellulose nanofiber characteristics
The extraction of cellulose nanofibers (CNFs) from lignocellulosic biomass provides a sustainable alternative to synthetic materials due to their biodegradability, mechanical strength, and environment...
Accuracy of intraoral scanners for full-arch implant scanning in the Maxilla using horizontal scanbody
This laboratory study evaluated the accuracy of six intraoral scanner models (Primescan; Trios 4; Trios 5; Medit i700; i900; Itero Lumina) compared to a desktop scanner (E4) used as a control. Additio...
Efficient authentication system based on blockchain for E-government
With the rapid development of smart cities, e-government has emerged as a key application of information and communication technology (ICT). However, current e-government systems face challenges such...
Sense-checking the approach to quantitative sensory testing to detect chemotherapy-induced peripheral neuropathy
People with chemotherapy-induced peripheral neuropathy (CIPN) have abnormalities in Quantitative Sensory Test (QST) findings. However, the predictive utility of QST for the early detection of CIPN in...
Construction of the Node—place—Jobs-housing model: Analysis of employment-residential ratio in subway station areas of Shenzhen, China’s highest construction density zone
Transit-oriented development (TOD) is widely recognized as a land development mode designed to integrate residential and employment spaces, fostering a balanced distribution of jobs and housing while...
Knowledge, attitude and practices among Healthcare Workers towards Pulmonary Plague Infection following an outbreak in Madagascar, 2017: A pilot study
Objectives To assess training needs of healthcare workers (HCWs) on pulmonary plague (PP) control after the large PP outbreak in Madagascar 2017....
Radon exposure and COVID-19 mortality in pre-vaccination period: What links might exist?
Radon, a naturally occurring radioactive gas known for its health risks, has recently gained attention for its potential protective role against COVID-19 mortality. This cross-sectional ecological stu...
The combined influence of chronic kidney disease and peripheral artery disease on long-term all-cause and cardio-cerebrovascular disease mortality among middle-aged and elderly individuals: A nationwide cohort study
Background The National Health and Nutrition Examination Survey (NHANES) is a nationwide program that evaluates the health and nutritional status of individuals in the United State...
How wear, age, and sex relate to enamel chipping in Cayo Santiago rhesus macaques (Macaca mulatta)
In living primates, bite forces required to fracture hard-object foods can result in high frequencies of chipped teeth, providing a comparative basis for inferring hard-object feeding in the fossil re...
Patterns of substance use in people with severe mental illness: A case-control study in Ethiopia
Background Substance use disorders are increasingly prevalent in sub-Saharan African countries, with evident bidirectional risk for people with severe mental illness (SMI) resultin...