PLoS ONE
Articles in this Issue
ACMTF-R: Supervised multi-omics data integration uncovering shared and distinct outcome-associated variation
The rapid growth of high-dimensional biological data has necessitated advanced data fusion techniques to integrate and interpret complex multi-omics and longitudinal datasets. Shared and unshared stru...
Feasibility trial of a transdiagnostic individual lifestyle evaluation and intervention (Lev-i) for health behavior change
Purpose Individuals with disabilities face challenges in adopting and maintaining healthy behaviors. Existing interventions are often diagnosis-specific, profession-bound, and limi...
Cohort profile: The Bristol IVF Study- A longitudinal study of women, their partners and treatment outcomes following assisted reproductive technologies
Background The Bristol IVF Study (BRIST-IVF) is a longitudinal clinical cohort, established to determine factors related to successful live birth and other outcomes following conce...
Air pollution macro-regions identification using machine learning and spatio-temporal analysis
Air pollution caused by suspended particulate matter (PM) remains one of the key environmental challenges in Poland, particularly in the context of public health and spatial planning. This study prese...
ViSQA: A benchmark dataset and baseline models for Vietnamese spoken question answering
Spoken Question Answering (SQA) extends machine reading comprehension to spoken content and requires models to handle both automatic speech recognition (ASR) errors and downstream language understandi...
Adverse events following Synflorix vaccination reported to the Vaccine Adverse Event Reporting System (VAERS), 2010–2024
Background Synflorix is a conjugate vaccine targeting Streptococcus pneumoniae, effectively reducing pneumonia and invasive pneumococcal disease in children under five. To evaluate...
Sex differences in cachexia outcomes and branched-chain amino acid metabolism following chemotherapy in aged mice
Cachexia is a complex muscle wasting syndrome that affects the majority of hospitalized cancer patients receiving chemotherapy. It is often unresponsive to nutritional interventions, including provisi...
Data management for distributed computational workflows: An iRODS-based setup and its performance
Modern data-management frameworks promise a flexible and efficient management of data and metadata across storage backends. However, such claims need to be put to a meaningful test in daily practice....
Synergistic antifungal effects of botanical extracts against Candida albicans
Antifungal resistance is growing increasingly more common due to the widespread use of limited number of antifungal compounds classes. Plant extracts have been used and studied for thousands of years...
Isothermal real-time RT-RPA for Machupo virus detection: Field-adaptable sensitivity comparable with laboratory PCR
Isothermal nucleic acid amplification methods, such as recombinase polymerase amplification (RPA), are becoming increasingly vital as diagnostic platforms for neglected tropical diseases by enabling r...
The ‘shades of grey’ in research integrity—Researchers admit to questionable research practices that they do not perceive to be serious
Research misconduct practices like fabrication, falsification and plagiarism (FFP) are serious deviations from good research conduct, which have attracted attention in the literature due to the damage...
Elevated anti-apoptotic shift in primary human aniridia limbal stromal cells following 48 hours supraphysiological glucose exposure, in vitro
Purpose Previous work demonstrated that supraphysiological glucose remodels TGF-β1 and NF-κB signaling in human limbal stromal cells (LSCs) and congenital aniridia-derived LSCs (AN...
GermVersity: A free and user-friendly interface to enhance the visualization and analysis of genebank data
Genebanks are crucial for food security and industrial applications. However, their heterogeneous nature hinders effective utilization. To address this, the GermVersity platform was developed to integ...
Robust motion detection and classification in real-life scenarios using motion vectors
In dynamic settings such as security, autonomous driving, and robotics, effective motion detection and classification are crucial for accurate tracking amidst target and background movements. Traditio...
The Demodifier: A tool for screening modification-induced alternate peptide taxonomy in palaeoproteomics
In palaeoproteomic research, the accuracy of taxonomic matches is crucial, as research questions frequently hinge on which species were utilised by ancient people. However, protein modifications inclu...
A monoclonal antibody raised against Acinetobacter baumannii capsular carbohydrate exhibits cross-species in vitro binding against Pseudomonas aeruginosa
The emergence of extensively drug-resistant bacterial pathogens such as Acinetobacter baumannii and Pseudomonas aeruginosa...
A knowledge graph construction method for compliance review of water conservancy project reports
To break through the efficiency and accuracy bottlenecks of manual mode in the compliance review of water conservancy project reports and promote the digital transformation of “Smart Water Conservancy...
Impacts of gender disparities in mental health and quality of life: A cross-sectional study of Brazilian physicians
Background Physicians are a professional group at high risk of impaired quality of life (QoL) and mental health due to heavy workloads, exposure to suffering, and structural inequa...
Development and validation of the HPV-WAK questionnaire for assessing women’s awareness and knowledge in Iran
Background Evidence indicates that knowledge about Human Papillomavirus remains limited in Iran. This study aimed to develop and psychometrically validate the Human Papillomavirus-...
SkelFormer: An adaptive hierarchical transformer-based approach on skeleton graphs for human action recognition in video sequences
Human skeleton-based action recognition represents a pivotal field of study, capturing the intricate interplay between physical dynamics and intentional actions. Current research primarily focuses on...
Research on thermo-mechanical coupling behavior of plasma-sprayed mullite ceramic coatings on concrete surfaces
This study systematically investigates the thermo-mechanical coupling behavior of plasma-sprayed mullite ceramic coatings on concrete surfaces through integrated finite element simulation and experime...
Dynamic interdependence between consumer confidence and housing prices: Evidence from bootstrap rolling window causality tests
This paper examines the bidirectional relationship between consumer confidence (CC) and housing prices (HP) using a bootstrap sub-sample rolling causality test. The results show that CC and HP interac...
Redundancy of macrobenthic functional traits boosts resilience to a simulated heatwave
Climate change is affecting ecosystems worldwide. Ocean temperature is increasing, leading to more frequent and intense extreme weather events such as heatwaves (HWs) and marine heatwaves (MHWs). Thes...
Egg quality characteristics of South African Potchefstroom Koekoek and commercial Lohmann brown layer chickens: A comparative study
Egg quality is an important feature in egg production and is affected by many factors, including the genetic makeup of the bird. However, the influence of the chicken genotype on egg quality traits is...
Vinyl chloride oligomers: On the road to understand the potential toxicity of PVC nanoplastics
On the road to understand the toxicity of nanoplastics, it is important to determine their capacity to interact with other molecules, as this is the first condition that must be met. In particular, po...