PLoS ONE
Articles in this Issue
U.S. trends of anti-vascular endothelial growth factor use from 2017–2023: An analysis of medicare, medicaid, and commercial insurance
Purpose Anti-vascular endothelial growth factor medications are a cornerstone in the treatment of many macular diseases in modern ophthalmology. These medications accrue significan...
Symptomatic chikungunya and chronic post-infection arthralgia in a highly endemic setting in Northeastern Brazil, 2018–2019: Clinical characteristics, prevalence and associated factors
Chikungunya, an Aedes -borne disease, poses a significant global health threat due to its substantial morbidity. The prevalence of symptomatic chikungunya virus...
Estimating actual striking forces using attenuation properties of Taekwondo protectors
Background: Protectors significantly attenuate impact forces, yet their quantitative characteristics remain poorly understood. While accurately measuring actual striking force is e...
A TGFB2/TNF-induced in vitro model of proliferative vitreoretinopathy (PVR) using ARPE-19 cells confirms nicotinamide as an inhibitor of EMT and VEGFA secretion
Proliferative vitreoretinopathy (PVR) is a vision-threatening fibrotic retinal disorder characterized by the epithelial-mesenchymal transition (EMT) of retinal pigment epithelial (RPE) cells. In this...
Drug price dynamics following changes in procurement method in the public healthcare setting in Malaysia
Pooled and segmented procurement are common in public health, but changing needs may prompt method shifts. Understanding their impact on drug prices is crucial for informed policy decisions. This stud...
RUL prediction method based on sequential health index evaluation with multidimensional coupled degradation data
Remaining Useful Life (RUL) prediction is crucial for implementing predictive maintenance strategies, however, RUL prediction is severely constrained by the lack of high-quality labeled life-cycle dat...
Research on missing value prediction of measured ERT data for coal mine based on a GRNN algorithm
In the process of long-term monitoring of the coal seam floor of a coal mining face using electrical resistivity tomography (ERT), the data loss caused by electrode disconnection adversely affects ear...
Using GDACS to anticipate clinical and operational burden after earthquakes: A global event-level analysis (2020–2024)
Global Disaster Alert and Coordination System (GDACS) alerts are widely used after earthquakes, yet their clinical relevance is uncertain. We performed a retrospective, global, event-level study spann...
Barriers and facilitators of tuberculosis treatment adherence among nomadic populations in Sub-Saharan Africa: A scoping review protocol
Introduction Tuberculosis (TB) is a notable public health issue in sub-Saharan Africa (SSA), disproportionately affecting vulnerable populations such as nomads. Their migratory lif...
Genotype distribution and risk factors of Toxoplasma gondii infection in animals of Trishal, Bangladesh
Toxoplasma gondii is a globally significant parasite with no genotyping data available from Bangladesh. This study aimed to determine the genotype distribution and associated risk...
Methamphetamine use disorder, perceived impacts, and associated factors among adults receiving care at Sri Lanka’s National Institute of Mental Health: An analytical cross-sectional study
Methamphetamine addiction poses a growing public health challenge in Sri Lanka, yet limited research explores its impacts on the addicted population. This study aimed to assess the severity, patterns,...
Biomechanical optimization of iliolumbar fixation strategies for unilateral vertical sacral fractures: Prioritizing stability-mobility balance via finite element analysis
Objective This study aims to optimize iliolumbar fixation strategies for unilateral vertical sacral fractures via finite element analysis, by comparing stability, implant stress, a...
When did you leave home? Reconstructing juvenile life histories of coastal Washington adult coho salmon (Oncorhynchus kisutch) using otolith structure and chemistry
Coho salmon ( Oncorhynchus kisutch ) can express a range of juvenile life history strategies and understanding how they contribute to adult returns is critical...
Impact of COVID-19 on colorectal cancer screening in a federally qualified health center: Provider and staff perspectives
The COVID-19 pandemic and associated policies discouraging routine-care visits dramatically affected cancer screening in the United States. Yet little is known about the perspectives of providers and...
Colorectal cancer incidence, survival analysis and predictions (Monastir, Tunisia: 2002–2030)
Background Colorectal cancer (CRC) ranks as the third most common cancer and the second leading cause of cancer death in Tunisia. The aim of this study was to describe the incidenc...
Correction: Understanding the role of Shroom3 in the developing mouse myocardium
The mediation effect of attitude on the association between knowledge and practices toward air pollution among commercial drivers and traders in South-Western Ghana: A cross-sectional study
There are extant studies on the knowledge, attitudes and practices of air pollution in sub-Saharan Africa and Ghana, however, studies among commercial drivers and traders in transport stations in Ghan...
Large gaps in monitoring urban air pollution in low- and middle- income countries associated with economic conditions and political institutions
Ambient air pollution has highly adverse effects on public health and the environment, particularly in urban areas of low- and middle- income countries (LMIC). Systematic air quality monitoring (AQM)...
Top food categories contributing to Canadian children’s energy and nutrient intakes at school
Introduction Understanding the foods and beverages that children consume at school can help inform the development of school food programs, which has become a priority in Canada fo...
Barriers and facilitators to establishing Early Psychosis Intervention (EPI) services in remote and rural communities across Canada
Aims There is a paucity of data on how Early Psychosis Intervention (EPI) services adapt to the challenges of rural practice, including geographical isolation and provider shortage...
Correction: Correction: A machine learning approach for estimating forage maize yield and quality in NW Spain
Consumer preferences for the development of new emulsion products based on vegetable and animal fats
The purpose of this paper was to determine consumer preferences for the acceptance of a new emulsion product containing interesterified fat based on mutton tallow and hemp oil. The survey concerned co...
Exploring the effects of arch support height on badminton sidestep cutting using musculoskeletal modeling
Sidestep cutting is a fundamental yet high-risk movement in badminton, often placing considerable biomechanical stress on the lower limbs. Arch support insoles are commonly used to improve foot stabil...
Research on road parametric modeling and dynamic lightweighting methods driven by BIM-GIS integration
Addressing the challenges of inflexibility and low modeling efficiency in the forward design of road building information modeling (BIM), as well as the performance bottlenecks within integrated BIM-G...
Laminin N-terminus α31 regulates corneal epithelial cell adhesion and migration through modifying the organization and proteolytic processing of laminin 332
Laminin N-terminus α31 (LaNt α31) is a netrin-like protein generated by alternative splicing of the laminin α3 gene. While previously shown to regulate vascular permeability in vivo, its role in epith...