PLoS ONE
Articles in this Issue
Transmission status of lymphatic filariasis in hotspots of filarial infection, persistent districts of nepal during post-MDA surveillance
Background The lymphatic filariasis (LF) elimination program in Nepal was launched in 2003, three years after the implementation of a global program to eliminate lymphatic filarias...
The role of age and gender in the relationship between personality traits, quality of life, and decision-making about orthognathic surgery—A cross-sectional study
Objective To explore how age and gender shape the relationship between personality traits, quality of life (QoL), and a patient’s decision to undergo surgery for correction of dent...
Retraction: Phospho-Aspirin-2 (MDC-22) Inhibits Estrogen Receptor Positive Breast Cancer Growth Both In Vitro and In Vivo by a Redox-Dependent Effect
Custom foot orthoses for chronic metatarsalgia: Study protocol for a participant- and assessor-blinded superiority randomized controlled trial
Background Chronic metatarsalgia (CM) causes significant pain and disability, affecting quality of life. Foot orthoses (FOs) including medially wedged designs with a metatarsal pad...
Increasing the working hours of nurses and teachers: Evidence from a discrete choice experiment
The healthcare and education sectors suffer from shortages of nurses and teachers. Extending their working hours has often been proposed as a solution to reduce shortages. In this study, we conduct a...
A note on a generalized double series
By employing contour integration the derivation of a generalized double finite series involving the Hurwitz-Lerch zeta function is used to derive closed form formulae in terms of special functions. We...
Lack of social support associated with major depressive disorder in middle-aged and older adults from the United States: A propensity score-matched cohort study
Background and objective Current widely used depression assessment criteria may not accurately reflect the true prevalence of depression, and previous studie...
A practical optimization method for enhancing drilling efficiency in panel furniture manufacture
Drilling is one of the most complex processes in the manufacturing of panel-type furniture and has a significant impact on both production efficiency and takt-time stability. With the growing demand f...
Machine learning and network pharmacology identify keloid biomarkers (AMPH, TNFRSF9) and therapeutic targets (IL6, HAS2) for aloe-derived quercetin
Objective This study aimed to identify diagnostic biomarkers for keloid and explore potential therapeutic agents from traditional Chinese medicine (TCM) by integrating network phar...
Development and evaluation of a modular smoke evacuator for surgical smoke control
Background Surgical smoke generated during energy-based operations is a known hazard containing particulate matter (PM), volatile organic compounds (VOCs), and biological debris, w...
SmUDo (Smart Unit-Dose): Redefining efficiency, quality, and staffing strategies for optimized processes
Background The implementation of unit-dose dispensing systems (UDDS) in hospital pharmacies represents a major milestone in the digital transformation of medication therapy managem...
Preparation and in vivo effectiveness evaluation of heparin-loaded PLGA@PCL core-shell fiber small-diameter vascular grafts
Cardiovascular disease has become the leading cause of death. It is the common goal for researchers worldwide to develop small-diameter vascular grafts (SDVGs) which could meet clinical needs. In this...
Relationships among social support, decision self-efficacy, and decision regret in colorectal chemotherapy cancer patients: A mediating model
Objective This study aims to identify the factors associated with decision regret among colorectal cancer patients undergoing chemotherapy in China and to determine whether decisio...
The mediating role of internal motivation on the relationship between ethical leadership and employee performance in hospitals in Northern Jordan
Objective The study’s main aim is to investigate the influence of ethical leadership (EL) on employee performance (EP) through internal motivation (IM) from the perspectives of cli...
Mapping ActEarly: Using a child health map to evaluate a City Collaboratory programme on early promotion of good health and wellbeing
Background Public health is increasingly being viewed as the result of numerous interrelated elements within intricate systems. A systems mapping approach highlights the potential...
Identification of cell senescence-related genes in spontaneous preterm birth based on bioinformatics analysis and machine learning
Spontaneous premature birth (SPTB) is a common pregnancy complication; however, few studies have explored cell senescence-related markers in SPTB. Bioinformatics and machine learning approaches were u...
Association between mink coronavirus (MCoV), Campylobacter spp., and diarrhea in farmed mink (Neogale vison)
Diarrhea outbreaks significantly affect the health and growth of farmed mink, posing economic and welfare challenges. While various pathogens have been linked to mink diarrhea, the causes during the w...
A phenomenological study of differentiated instruction experience in an Ethiopian middle school: The case of grade 7 students in Hawssa city, Ethiopia
This phenomenological study investigates middle school students’ and their English language teacher’s experience with differentiated instruction in a writing classroom. The aim was delving into the li...
Prevalence of illicit alcohol consumption and associated factors among adolescents in selected communities of Lusaka, Zambia
Introduction Illicit alcohol (illegally brewed alcohol) consumption among adolescents is an increasing public health problem worldwide, with major impacts on individuals, families,...
A cross-sectional survey to explore healthcare providers’ experiences and attitudes toward HIV pre-exposure prophylaxis for women in family planning centers of Greater Paris
Despite representing a disproportionately high percentage of new HIV diagnoses in France annually, women who have migrated from Sub-Saharan Africa (WMSSA) remain underserved by HIV prevention strategi...
Effects of glycyrrhizin on healing and prevention of recurrent aphthous stomatitis in hamster models
Recurrent aphthous stomatitis (RAS), a major type of stomatitis, can significantly impair quality of life. The therapeutic and preventive effects of glycyrrhizin (GL), a compound known for its anti-in...
Correlation between self-regulatory fatigue and physical activity in lung cancer patients undergoing comprehensive treatment
Background Self-regulated fatigue is often assessed in studies of chronic diseases. Research is needed on the self-regulation of fatigue and physical activity in lung cancer patien...
Integrative GC-MS, network pharmacology, and molecular dynamics elucidate synergistic anti-diabetic mechanisms of Chongqing Citrus reticulata ‘Dahongpao’ volatile oil via multi-target stabilization
Background Diabetes mellitus involves complex pathogenesis requiring multi-target interventions. Citrus reticulata...
Jingfang granules inhibiting LPS-induced acute lung injury via regulating linoleic acid and arachidonic acid metabolism pathway
Acute lung injury (ALI) is a severe clinical syndrome with high mortality. Jingfang Granules (JFG), a modern formulation of the traditional Chinese medicine (TCM) compound Jingfang Baidu Powder, has b...
Prevalence and predictors of preconception medical and behavioral risks among soon-to-be married couples: A quantitative cross-sectional survey in Rwanda
Background Maternal and neonatal morbidities and mortality remain a global public health concern. Although preconception risk assessment has been found to enhance maternal, fetal,...