PLoS ONE
Articles in this Issue
A pilot effectiveness study of a just-in-time micro-randomized controlled trial on the physical activity and sedentary time of young children and their parents: The active family m-health intervention
Background Parents play a critical role in influencing their young children’s physical activity (PA) and sedentary time (ST). Despite this, many young children (aged 3-4y) and thei...
Effects of plyometric jump training on measures of physical fitness and lower-limb asymmetries in male soccer players according to maturity: A randomized controlled trial
The purpose of this study was to determine the effects plyometrics on dynamic balance, muscle power and lower limb asymmetries in youth soccer players according to maturity. 43 youth soccer players (2...
Lethal effect of heterologous Haemonchus contortus α- and β-tubulin expression in Leishmania tarentolae
Benzimidazoles are widely used anthelmintics that target β-tubulin and disrupt microtubule formation, yet the precise mode of action and resistance mechanisms in parasitic nematodes remains incomplete...
Investigating the influence of the physical environment on psychiatric nurses wellbeing and professional interactions: A convergent parallel mixed-method study protocol
Nurses in psychiatric hospitals face demanding working conditions, where high emotional burdens, unpredictable patient behavior, and safety concerns contribute to stress. Research highlights the signi...
Lifestyle factors and prevalence of semen abnormalities among men undergoing infertility evaluation at oak specialist hospital: A retrospective cohort study
Background Male infertility constitutes a notable health burden in Sub-Saharan Africa, contributing to approximately 40–50% of all infertility cases, compounded by cultural stigma...
Global, regional, and national burden of hip dislocation, 1990–2021, and Bayesian age-period-cohort predictions: Systematic analysis of the Global Burden of Disease study, 2021
Background Hip dislocation is a severe, clinically rare trauma. The global incidence, trends, and causes of hip dislocation have not been precisely documented. We aimed to explore...
Impact of COVID-19 restrictions on thyroid cancer diagnoses in a comprehensive cancer center (2017–2023)
Introduction The Coronavirus 2019 (COVID-19) pandemic disrupted healthcare delivery across the United States, leading to a sharp decline in outpatient visits. Given that thyroid no...
Effects of an information shock on registry-based health indicators: Evidence from a Swedish PFAS crisis
This study investigates how the public announcement of very high levels of the toxic chemicals PFAS in the drinking water in Kallinge, Sweden, impacted the health of local residents. By leveraging the...
Inhibition of HER2 signaling and breast cancer cell growth with a novel antibody targeting HER2 ECD III/IV
Human epidermal growth factor receptor 2 (HER2), a ligand-independent tyrosine kinase receptor belonging to the EGFR family, serves as a key oncogenic driver in breast, gastric, and several other soli...
From law enforcement to public safety: Police officer experiences of naloxone administration to reverse opioid overdose in New York City
The overdose epidemic has reshaped law enforcement’s relationship with public health, as police increasingly adopt overdose response measures, including naloxone training and use. This study analyzed...
Concurrent coverage and determinants of vitamin A supplementation and deworming among children aged 12–59 months in 15 Sub-Saharan African countries
Background Vitamin A supplementation (VAS) and deworming (DW) are proven, cost-effective interventions that protect children against preventable morbidity, mortality, and the burde...
Study on radial fracture mechanism of saturated granite subjected to coupled static–cyclic impact loading: An experimental investigation
The rock failure mode under coupled static-cyclic impact loading is not unified, and the radial fracture mode is a distinct type. In this study, cyclic impact tests were performed using a modified Spl...
“You could get the best of both breeds or the worst of both”: UK public attitudes towards crossbreeding in dogs - with a specific focus on brachycephalic dogs
Extreme conformation and reduced genetic diversity are recognised to lead to severely reduced health, welfare and longevity in certain dog breeds. There is growing interest in applying strategic cross...
A shot in the dark: Comparative morphology of the bioluminescent tube organs in tubeshoulders (Platytroctidae)
Bioluminescence, visible light produced by a living organism, is a key innovation in the diversification of deep-sea fishes. It is useful for a myriad of behaviors and interactions in deep-sea organis...
The impact of school absence on mental health in children and young people: Analysis of an English national birth cohort
Background Given concerns the role of school closures in increasing mental health problems after the Covid-19 pandemic, we used pre-pandemic data to undertake a causal epidemiologi...
Faster but less accurate: An explorative study on the effects of three weeks of ketogenic diet on cognitive functions in undergraduate students
The ketogenic diet (KD) is a low-carbohydrate diet that induces and sustains a ketosis state and minimizes somatic glucose levels. Several psychological studies have described the positive effects of...
Health and lifestyle in the Iron Age Italian community of Pontecagnano (Campania, Italy, 7th-6th century BCE)
This study investigates health, dental development, diet, and human-environment interactions in individuals buried in the necropolises of Pontecagnano (Campania, Italy, 7th-6th century BCE), using an...
Anal HPV shedding assessed by self-sampling and multiplex real-time PCR among men who have sex with men in N’Djamena, Chad: a feasibility and acceptability study
Background High-risk (HR) human papillomavirus (HPV) infection remains a great concern in sub-Saharan Africa in men who have sex with men (MSM). The prevalence of anal shedding of...
Observations of marine animal interactions with a small tidal turbine
The risk of collisions between animals and operating tidal turbines remains a concern in the scientific and regulatory communities. A sensor package including optical cameras was deployed to monitor a...
Human emotional odours influence horses’ behaviour and physiology
Olfaction is the most widespread sensory modality animals use to communicate, yet much remains to be discovered about its role. While most studies focused on intraspecific interactions and reproductio...
Sexual and reproductive health challenges among street adolescents in Sylhet city, Bangladesh: A cross-sectional study
Background Street adolescents often engage in early sexual activity, have multiple partners, and are at high risk of sexual abuse and exploitation. Despite the significance of this...
Entrepreneurial intention of students: The role of digital tools and personal factors in entrepreneurship education
Education is changing due to digital transformation, which is especially significant for entrepreneurship since students’ readiness to start their own businesses may be assessed by their proficiency w...
Effects of breathing exercise and thoracic techniques on pain and disability in low back pain: A systematic review and meta-analysis
Purpose The objective of this study was to systematically review the effectiveness of thoracic-focused interventions, including breathing exercises and thoracic manual techniques (...
Mobile phone MIMO antenna array miniaturization-based low SAR research in the combined EMF
Due to the diversification of media functions of mobile phones, users can make calls and access the internet simultaneously, which has significantly increased the usage time of mobile phones. The expo...
Comparing snowball sampling and RDS: A methodology and case study
Both snowball sampling and Respondent Driven Sampling (RDS) are used to sample hard-to-reach populations. Snowball sampling was initially developed as a probability sampling method, but in practice, i...