PLoS ONE
Articles in this Issue
Nest attributes influence choice accuracy, but not decision latency in acorn ants
Decision making can have significant fitness consequences across various aspects of animal life. For acorn ants, Temnothorax curvispinosus , choosing a new nest...
MViT: A vision transformer with fractal path reordering and dynamic positional encoding
Vision Transformers have demonstrated remarkable performance in image classification and structural modeling; however, fixed patch partitioning and static positional encoding often disrupt spatial con...
Identification of empagliflozin-related hub genes in atherosclerosis and their correlations with immune infiltration: Network pharmacology and bioinformatics analyses
Background Atherosclerosis (AS) is by far the most frequent underlying cause of atherosclerotic cardiovascular disease. Recently, sodium-glucose cotransporter 2 (SGLT2) inhibitors...
Gamma irradiation crosslinked fluorescent nanocarbon based biodegradable hydrogel for controlled release of antibiotics
Controlled and sustained antibiotic delivery is critical for combating antimicrobial resistance while minimizing side effects. Herein, a novel biodegradable hydrogel system, synthesized via gamma irra...
The neutrophil-to-lymphocyte ratio as a predictor of all-cause mortality in individuals with anemia: A population-based study
Background This study investigates the association between the neutrophil-to-lymphocyte ratio (NLR) and all-cause mortality in individuals with anemia using the National Health and...
Comparison of chemo-mechanical and conventional caries removal methods in 6-to-12-year-old children: Randomized clinical trial
Background To address the discomfort associated with conventional drilling for caries removal in children, a minimally invasive approach such as chemo-mechanical caries removal was...
Insights into the pathogenesis and differential diagnosis of clival lesions in an individual from a 16th-century-CE mass grave at Mohács (Southwestern Hungary)
The aim of our paper is to present and discuss in detail the pathological lesions suggestive of tuberculosis observed in a skeleton ( MMG3–75 ) that was excavat...
The influence of lime type on the properties of traditional lime-soil materials
The conservation of historic earthen structures requires repair materials that are both high-performance and historically appropriate. While archaeological evidence indicates that the historical use o...
To what extent do people in malaria-endemic countries know asymptomatic malaria infections? A systematic review
Introduction Malaria is a parasitic disease caused by Plasmodium parasite and transmitted to humans by infected f...
Supporting mental well-being of healthcare workers using a mobile app: A mixed-methods feasibility study
Poor mental well-being is common among healthcare workers, affecting individual health, patient safety, and organisational performance. Mobile app-based self-care interventions are promising due to th...
To see or not to see the vet: A vignette-based study of decision-making by UK dog owners regarding seeking veterinary care for commonly presenting conditions
Barriers to accessing veterinary-care for dog-owners are diverse and dynamic, and widely accepted as major canine welfare threats because of potential non-, under- or delayed treatment. Owner knowledg...
“It’s a last straw situation”; Overdose response and preferences for seeking support from emergency services during overdose in rural Ohio
Objectives We assessed how people who use drugs in rural Ohio communities affected by the opioid epidemic respond to overdose, their preferences for seeking support from first resp...
The role of sex education in withdrawal use: Prevalence and correlates among a nationally representative sample of adolescents and young adults
Objectives Instances of withdrawal, the practice of removing a penis from a vagina before ejaculation to prevent pregnancy, have increased in some US populations over the past two...
Investigation of a viable but non-culturable state in Porphyromonas gingivalis and host cell invasion
Porphyromonas gingivalis ( P. gingivalis ) is a gram-negative, black-pigmented, anaerobic pathogen known for its biofilm formation and its c...
Effects of export sophistication on marine pollution: Evidence from Chinese coastal regions
Trade liberalization has accelerated export growth in China’s coastal regions, becoming a major driving force behind local economic development. However, this rapid expansion has also imposed severe e...
Mono-mix strategy enables comparative proteomics of a cross-kingdom microbial symbiosis
Cross-kingdom microbial symbioses, such as those between algae and bacteria, are key players in biogeochemical cycles. The molecular changes during initiation and establishment of symbiosis are of gre...
Drug-loaded nanoparticles for intra-articular injection
Drug loaded nanoparticles (NPs) were developed as a model intra-articular injection (IAI) formulation to mitigate early stage osteoarthritis (OA). Different types of celecoxib-loaded nanoparticles wer...
Exploring novel semi-inner product reproducing Kernels in Banach space for robust Kernel methods
Kernel methods are widely applied across various domains; however, structural limitations of reproducing kernels in Hilbert spaces pose significant challenges. Many challenges inherent to Hilbert spac...
Prevalence, risk factors, and viral load quantification of HBV infection among hospital patients: A cross-sectional investigation in Mogadishu, Somalia
Background Hepatitis B virus (HBV) remains a major public health challenge in sub-Saharan Africa. Somalia, with its fragile healthcare system and high-risk population, lacks up to...
End-of-life care stress in korean pediatric nurses: A cross-sectional analysis of related perceptions, attitudes, and self-efficacy
Pediatric end-of-life (EOL) care imposes a significant emotional burden on nurses, often leading to elevated stress. Psychological factors, such as perception, attitude, and self-efficacy, are known t...
Fusion of multi-scale geometric features and frequency domain decomposition for stereo matching network
In learning-based stereo matching methods, a feature information-rich and concise cost volume is crucial for achieving high-precision and high-efficiency stereo matching. Aiming at the problem that th...
Beyond the skin: Lived experiences and coping strategies of psoriasis patients in Malaysia
Background Psoriasis is a chronic autoimmune skin condition that significantly impacts an individual’s quality of life, resulting in physical discomfort, psychological distress, an...
Evaluation of the marginal and internal gaps in 3D-printed interim crowns using different finish line detection methods: An in vitro study
Objective This study aimed to evaluate the accuracy of the Dentbird crown software in automatically detecting the finish line for interim crowns....
Public participation in healthcare safety: A tripartite evolutionary game model with evidence from diverse international cases
As healthcare systems grow in complexity, ensuring medical safety requires moving beyond traditional top-down regulation. While public participation is increasingly recognized as a vital component, a...
Conjugation of a Cryptococcus neoformans-derived metalloprotease to antifungal-loaded PLGA nanoparticles treats neural cryptococcosis in an in vitro model
Overcoming the blood-brain barrier to deliver therapeutics is a major hurdle in treating diseases of the central nervous system. We engineered 4-arm carboxyl terminated poly(D,L-lactide-co-glycolide)...