PLoS ONE
Articles in this Issue
Cheminformatics-driven discovery of natural isoquinoline alkaloid inhibitors of Beta-secretase I for Alzheimer’s management
Alzheimer’s disease (AD) is characterized by the gradual deterioration of cognitive functions, speech impairment, and memory loss. It can potentially be treated by targeting the beta-site amyloid prec...
Psychosocial career preoccupation and organisational commitment at higher educational institutions in Ghana: The role of workplace friendship
Empirically, the study examined how psychosocial career preoccupation [PCP] directly affects organizational commitment [OC] and indirectly affects the same via workplace friendship [WF] among administ...
Cognitive impairment and depressive symptoms to predict renal outcome and mortality in older adult patients
Cognitive impairment and depressive symptoms are common in older adults, but their impacts on adverse renal and survival outcomes remain unclear. This retrospective cohort study examined associations...
Comparative analysis of the diversity within the B. bronchiseptica fimX locus
Bordetella bronchiseptica is a highly contagious veterinary bacterial respiratory pathogen with a broad host range that can cause a variety of clinical disease outcomes ranging fro...
Evaluation of peripheral intravenous line securement devices under clinically relevant loading and perspiratory conditions
Peripheral vascular access devices (PVADs) and their associated intravenous (IV) lines are widely used in clinical care. Securement devices are typically employed to prevent accidental dislodgement an...
Comparative outcomes of DSAEK and DMEK in eyes with prior Ahmed glaucoma valve implantation
Background To compare the outcomes of Descemet stripping automated endothelial keratoplasty (DSAEK) and Descemet membrane endothelial keratoplasty (DMEK) in eyes with prior Ahmed g...
Impact of timing from last dose of dexamethasone administration to delivery, different steroid courses, and fetal number on preterm neonatal outcomes
Objectives To evaluate the impact of the timing from the last dose of dexamethasone to delivery, different steroid courses, and the number of fetuses (singleton vs twin) on preterm...
Blood gas and lactate analysis in nesting loggerhead (Caretta caretta) and green (Chelonia mydas) sea turtles from southeastern Florida, USA
High-energy demands and transition to a catabolic state pose physiological challenges for sea turtles during the nesting season. The objectives of this study were to assess venous blood gas analytes a...
A comparative analysis of HIV status by sociodemographic and sexual behavior characteristics among men in Bexar county, Texas: An Ending the HIV Epidemic priority county
A combination of sociodemographic and sexual behaviors is associated with HIV status awareness. We collaborated with HIV service organizations to collect survey data from 389 men in Bexar County, Texa...