PLoS ONE
Articles in this Issue
Cost-effectiveness of primary HPV genotyping and dual-stain or cytology reflex testing versus cytology-based screening for cervical cancer in Chile
Testing for high-risk human papillomavirus with genotyping for types 16 and 18 (HPV16/18) and triage by p16/Ki-67 dual-stain immunocytochemistry improves diagnostic performance in cervical cancer scre...
Retraction: FoxO3a Modulates Hypoxia Stress Induced Oxidative Stress and Apoptosis in Cardiac Microvascular Endothelial Cells
A longitudinal comparison of symptom-distress and person-centeredness between a fast-track programme for cardiac surgery and conventional care
Aim and design Impaired recovery in the post-operative phase after cardiac surgery predicts long-term recovery, making it important to identify and treat symptoms immediately. A fa...
Selective culinary uses of plant foods by Northern and Eastern European hunter-gatherer-fishers
Carbonised food deposits preserved in pottery vessels, often termed ‘foodcrusts,’ are frequently encountered on hunter-gatherer-fisher (HGF) pottery throughout Northern and Eastern Europe. While lipid...
Correction: Seroprevalence of diphtheria and tetanus antibodies among children and adolescents in high- and low-immunization coverage areas in the Lao People’s Democratic Republic
Description of the geographic distribution of excessive drinking across regional cultures in the United States: Framing an important health metric according to the cultural context of the American nations
Excessive alcohol drinking results in an increased risk for chronic diseases, and the rates of alcohol consumption have increased among U.S. adults in the past decade. The U.S. Surgeon General called...
Environmental changes and their effects on carbon isotope distribution in Lake Plateliai over the past 130 years: insights from sediment organic fractions and diatom assemblages
In this study, we investigated how anthropogenic activities have affected the carbon cycle and biological productivity in a mesotrophic lake over the past 130 years. We analysed the carbon isotope dis...
Shaping industrial spatial density: How floor area ratio varies across regions and sectors in Zhejiang, China
Spatial density plays a pivotal role in influencing land-use patterns and land consumption. To meet evolving industrial needs and maximize limited land resources, incorporating floor area ratio (FAR)...
Pay gaps in the National Health Service: Gender and sexuality
Studies investigating the relationship between gender, sexual identity and pay have increased in number and scope over the last three decades, enabling a greater understanding of the outcomes facing L...
MAAR-Net: Multi-scale attention-assisted residual neural network for renal microvascular structure segmentation
Renal disease represents a significant public health concern, with renal microvascular lesions playing a crucial role in disease progression. Accurate segmentation of this microvasculature is therefor...
Preoperative hypocalcemia predicts postoperative complications in older orthopedic patients: A multicenter cohort study
Background Serum calcium, a key biochemical marker in the body, plays a crucial role in maintaining bone health. Nevertheless, research exploring the link between preoperative seru...
Community awareness, perceptions, and management practices related to pre-eclampsia: An exploratory qualitative study in Mbale City, Eastern Uganda
Background Pre-eclampsia and other hypertensive disorders of pregnancy are the second leading cause of maternal mortality globally, with 95% of deaths occurring in low- and middle-...
Comprehensive analysis of mortality risk factors in low-grade B-cell lymphoma
Background Low-grade B-cell lymphomas (LGBCLs) account for approximately 40% of non-Hodgkin lymphomas with low progression. LGBCL is divided into subgroups, which share common comp...
Innate defense mechanisms against Nosema ceranae in hygienic honey bee (Apis mellifera) colonies
The honey bee colony ( Apis mellifera ) acts as a superorganism, with a dual immune system that operates at the individual and social level. However, the linkag...
Structural and phylogenetic insights from complete chloroplast genomes of seven Vicia species
The legume genus Vicia L. (Fabaceae) is of significant ecological and agronomic importance, comprising species widely utilized as forage crops, green manure, an...
The choice of corporate social responsibility strategies under rivalry: Whether to increase socially responsible product characteristics or enhance relationship with buyers
Corporate social responsibility (CSR) theory emphasizes both CSR characteristics in products and CSR activities to enhance relationships with buyers. However, there are theoretical gaps regarding the...
The dynamics of educational transformation: Empirical insights into how innovation, collaboration, and professional development influence digital resource usage across 81 countries
This study addresses a critical gap in understanding how teacher innovation drives the utilization of digital resources in education, mediated by teachers’ self-efficacy and collaboration, and moderat...
Academic integrity across educational levels: Exploring students’ engagement with grey-zone and non-compliant practices in four European countries
To foster academic integrity in students and future scholars, it is essential to understand how their integrity behaviours evolve throughout their educational trajectory and across various academic in...
Serum biomarkers for predicting Crohn’s disease activity: The role of bilirubin, uric acid, and the C-reactive protein/albumin ratio
Background Crohn’s disease is a chronic, progressive inflammatory condition of the gastrointestinal tract that requires long-term assessment of disease activity. There is a growing...
Combining transcranial direct current stimulation and computerized cognitive training for post-stroke cognitive recovery: Study protocol for a randomized controlled trial with optimized temporal intervention sequences
Background Post-stroke cognitive impairment is a common and severe complication of stroke, significantly affecting patients’ daily life and rehabilitation. Although transcranial di...
Accuracy of owner-reported diagnoses for dogs enrolled in the Dog Aging Project as compared to veterinary electronic medical records
The objective of this project was to evaluate the accuracy of owner-reported health diagnoses in dogs compared to veterinary electronic medical records (VEMRs) using data from the Dog Aging Project (D...
Identifying high-risk combinations of metformin during COVID-19
Background There is a lack of research addressing associations of antidiabetic drug combinations with COVID-19 deaths. We examined whether adding common second-line agents to metfo...
Association between intrinsic capacity trajectories and risk of stroke incidence in middle-aged and older chinese adults: Evidence from a nationwide prospective cohort study based on CHARLS
Background Stroke is a major public health concern and a leading cause of disability and death in aging populations. Intrinsic capacity (IC), a concept introduced by the World Heal...
The frequency, risk factors and spatial distribution associated with having a diagnosis of leishmaniosis in dogs in the UK in 2019
Background Leishmaniosis in dogs is an important zoonotic disease, endemic in southern Europe but is increasingly being recorded in other parts of Europe including the UK. This stu...
Exploring measures of sustainability in the WHO Joint External Evaluation and the WOAH performance of veterinary services tools—A qualitative assessment of perceived usefulness and acceptability to one health and global health security experts
Introduction Amidst global policy reforms including the 2024 amendments to the International Health Regulations (IHR) and the ongoing Pandemic Agreement negotiations, there is a re...