PLoS ONE
Articles in this Issue
An optimization scheduling model of multi-energy virtual power plants considering uncertainty constraints and multi-energy coupling characteristics
Existing research on virtual power plants (VPPs) has not fully integrated the coupling relationships among electricity, heat, hydrogen, and carbon, and scheduling strategies under uncertainty conditio...
Tonsil-derived mesenchymal stem cells alleviate skin inflammation by modulating neutrophil extracellular trap formation and T cell migration
Skin inflammation arises from complex interactions among immune cells, particularly T cells and neutrophils. Mesenchymal stem cells (MSCs) exhibit potent immunomodulatory properties, but the specific...
The role of prehabilitation in improving brain health and cognition after chemotherapy in patients with colorectal cancer: Study protocol of the Chemo Brain Prehab Project
Introduction Regional disparities in the incidence of colorectal cancer remain a concern within the United Kingdom, particularly in the North West of England, with 37% higher incid...
Protocol for a systematic review and meta-analysis of pharmacological and non-pharmacological interventions for chronic pain management in chronic kidney disease
Background Chronic pain affects up to 60% of people with chronic kidney disease (CKD), yet remains under-recognised and under-treated. Pain management in this population is complic...
COVID-19 knowledge, attitudes, and practices among people vulnerable to HIV in Uganda: A cross-sectional cohort analysis
Background People with behavioral vulnerability to HIV face barriers to healthcare engagement that may impede uptake of non-pharmaceutical and other interventions to prevent COVID-...
Integrating sequence-based GWAS and comparative genomic analysis reveals conservation and species-specificity of putative functional variants influencing tail length and tail abnormalities in pigs and sheep
Long tails trigger tail biting in pigs and increase the risk of flystrike infections in sheep. Tail docking has been a common management practice in both species for decades, but increasingly conflict...
Retraction: Induction of heat shock protein expression in SP2/0 transgenic cells and its effect on the production of monoclonal antibodies
Class switching toward IgG4 six months after primary mRNA-based COVID-19 vaccination in kidney patients
Background Class switching toward spike (S)-binding IgG4 antibodies after mRNA-based COVID-19 vaccination has been observed, an antibody subclass with strong neutralizing but limit...
Mental health help-seeking intentions among health workers in the east coast of peninsular Malaysia: Perceived barriers and predictive factors
Introduction Mental health problems among health workers are a growing concern globally, including in Malaysia. Despite the availability of mental health services, some health work...
The 30-year evolution of motor vehicle road injuries: Can the future come from the shadows?
Background This study examines temporal changes from 1990 to 2021 in the burden of vertebral fractures (VFs) attributable to motor vehicle road injuries (MVRIs), with a particular...
A biologically plausible decision-making model based on interacting neural populations
We present a novel decision-making model with two populations. Each population is composed of Regularly Spiking (excitatory) and Fast Spiking (inhibitory) cells in cortical layer 2/3. Each population...
UHPLC-QTOF-MS/MS-based metabolomic discovery of anticancer compounds in ethanolic extracts of Ficus hispida L. f.
Ficus hispida L. f. ( F. hispida ) is commonly used in traditional medicine for various health problems. No comprehensive analysis of all it...
Computational frameworks for automated detection and quantification of paroxysmal sympathetic hyperactivity among traumatic brain injury patients
Paroxysmal sympathetic hyperactivity (PSH) is a syndrome that occurs in a large subset of critically ill traumatic brain injury (TBI) patients and is associated with complications and poor recovery. P...
Correction: Children’s outdoor play at early learning and child care centres: Examining the impact of environmental play features on children’s play behaviour
Protocol for the establishment of the Pediatric Registry for Stroke as a Multidisciplinary Approach to healthcare research (PRiSMA) study
Background Childhood stroke is a rare but potentially life-threatening event that can occur at any age. It requires prompt diagnosis and appropriate treatment, and, in view of the...
Socioeconomic priorities and stunting in rural indonesia: A mixed-method study
As part of the plan to lower the stunting rate by up to 14% in Indonesia in 2024, a nutritional intervention program for stunted children was implemented in 2023. The program, which ran for four month...
Person-centered practice in the Portuguese healthcare system: A documentary study
Background Person-centered practice has increasingly become a key structural component of health systems, driving the progressive reformulation of public health policies internatio...
Post-hospital physical rehabilitation for physical function recovery among community-dwelling survivors of critical illness: A systematic review protocol
Introduction Many survivors of critical illness experience lasting physical disability. Post-hospital rehabilitation has the potential to reduce this physical disability; however,...
Exploratory study on the impact of Ganoderma australe extract on gut microbiota and immune gene expression in honey bees exposed to Vairimorpha ceranae
The microsporidium Vairimorpha ( Nosema ) ceranae is an emerging threat to honey...
“The system is a bit broken…” a qualitative exploration of barriers in the pathway for diagnosing Developmental Coordination Disorder
Background Approximately 5% of children are affected by a neurodevelopmental disorder of their sensorimotor skills. DSM-V and ICD-10, the two most widely used diagnostic systems, d...
Hybrid lightweight vision transformers with attention mechanism for feature extraction and classification of product designs
In modern consumer markets, product packaging strongly influences customer attention and buying decisions. Attractive and informative designs help brands stand out in competitive environments. Recentl...
Integrated light and electron microscopy workflow for morphological, molecular and ultrastructural analysis of spheroids
Traditional two-dimensional cell cultures are limited in their ability to accurately model cancer progression and treatment response, which has prompted researchers to develop three-dimensional...
RETRACTED: A novel method based on clustering and decision-making for construction project portfolio selection
Nowadays, the problem of project portfolio selection is one of the important tasks in many construction organizations, especially project-based ones. On the other hand, project portfolio selection usu...
Calculation of ultimate bearing capacity and analysis of bearing characteristics for pile group foundation to underlying offset cave
Based on the pile group effect and the principle of limit analysis, a equation is derived for calculating the ultimate bearing capacity of pile group foundations under the condition of offset karst ca...
Designing and evaluating the acceptability of a psychosocial and socioeconomic support package for people with drug-resistant tuberculosis in Johannesburg, South Africa
Drug-resistant tuberculosis (DR-TB) is a global health problem that presents multifaceted challenges to people living with the disease. These challenges lead to sub-optimal adherence in some DR-TB pat...