PLoS ONE
Articles in this Issue
Effects of increasing molybdenum under low nitrogen input on yield, nitrogen-metabolizing enzymes and nitrogen use efficiency of winter wheat cultivars
In wheat production, improving resource utilization and grain yield has been a longstanding goal that researchers have been pursuing. This study aimed to investigate whether regulated nitrogen (N) and...
Chlorine dioxide flushing protocols for microbial reduction in dental chair units
Dental chair unit (DCU) waterlines are often microbiologically contaminated. This poses infection risks for patients and dental staff if they are not regularly rinsed and disinfected. This clinical hy...
Correction: Efficient authentication system based on blockchain for E-government
Correction: Adherence to intravenous chemotherapy and associated factors among patients with cancer at Hawassa University Comprehensive Specialized Hospital Cancer Treatment Center, Sidama Region, Southern Ethiopia
Disaggregating innovation for sustainable development in ASEAN: Panel evidence on the moderating role of government effectiveness
With progress toward the 2030 Agenda faltering, many see innovation as a key to sustainable development. The Association of Southeast Asian Nations (ASEAN) bloc represents a unique opportunity to exam...
Detection of spike protein in term placentas of COVID-19 vaccinated and/or SARS-CoV-2 infected women
Introduction COVID-19 (Corona Virus Induced Disease-19) caused by the SARS-CoV-2 coronavirus can be a serious in pregnancy. Therefore, vaccination with modRNA vaccines was recommen...
Gastrin ameliorates heart failure and suppresses myocardial remodeling via the JAK2/STAT3 and ERK1/2 pathways
Background Previous studies have indicated elevated serum gastrin levels in individuals with HF. However, the association and underlying mechanisms between gastrin and HF remain un...
Contraceptive use intention among women in Pakistan: Application of theory of planned behavior
Introduction Unintended pregnancies remain a major public health concern globally and in Pakistan, where family planning (FP) uptake continues to be hindered by entrenched social a...
MLGT: A multimodal graph attention network for virtual screening of anti—Uveitis drugs
Uveitis is a severe ocular inflammatory disease with complex immune—mediated pathogenesis, posing significant challenges for drug discovery. While artificial intelligence has accelerated virtual scree...
Understanding security challenges in the software supply chain through causal relationships
In recent years, the Software Supply Chain (SSC) has become a key target for cyberattacks due to its complex structure and dependence on third-party and open-source components. These attacks pose seri...
Chest drain REgular FLushing in ComplIcated parapneumonic EFfusions and empyemas: Study protocol for the RELIEF randomized controlled trial
Background Pleural infections are common and drainage of the pleural space, in addition to antimicrobial therapy, is often required for adequate treatment. Guidelines suggest flush...
Clinical outcomes in hospitalized patients with community-acquired pneumonia: A comprehensive analysis of associated factors
Background Community-acquired pneumonia (CAP) remains a significant cause of hospitalization and mortality globally. Optimizing clinical outcomes in CAP depends heavily on timely,...
Perspectives of military-affiliated women on lethal means safety: A systematic review
Background Women are the fastest-growing military cohort, with suicide rates rising faster than among veteran men and civilian women. Lethal means include firearms, used more often...
Geographical indications and health-conscious behaviors among nursing students: A mixed methods study
This study was conducted using a Sequential Explanatory Design, in which the quantitative phase was carried out first, followed by a qualitative phase to examine the influence of nursing students’ att...
Editorial Note: A survey of public attitudes toward uterus transplantation, surrogacy, and adoption in Japan
Expression of Concern: Dual-hybrid intrusion detection system to detect False Data Injection in smart grids
Visual intelligence for efficient human action recognition in human computers interaction applications
Human Action Recognition (HAR) is a pivotal area in computer vision, video surveillance, and human-computer interaction (HCI), driven by the need for efficient and accurate models to enhance HCI exper...
Understanding the direct and indirect impacts of disease response phenotypes on chicken coccidiosis epidemiology: A modelling approach
Coccidiosis, a widespread disease in poultry caused by protozoan parasites of the genus Eimeria, leads to significant economic losses. The increasing resistance of Eimeria species to anti-parasitics,...
High-performance eco-concrete beams with calcined montmorillonite, metakaolin pyrolyzed coffee grounds, and hybrid fibers for enhanced bending strength and microstructural refinement
This study investigates the flexural performance and microstructural evolution of reinforced concrete beams incorporating calcined montmorillonite (CMMT), metakaolin (MK), pyrolyzed coffee grounds (PC...
Global, regional, and national burden of nonalcoholic fatty liver disease among adults aged ≥ 45 years: A comprehensive analysis of epidemiological trends and projections to 2035
Background Nonalcoholic fatty liver disease (NAFLD) has emerged as the leading cause for chronic liver diseases around the globe, disproportionately affecting aging populations. Th...
Huanggan decoction ameliorates cholestatic hepatic fibrosis in rats via TGF-β1/Smad3 signaling pathway
Background Huanggan Decoction (HGD), as a special Chinese medicine preparation, has good effects in clearing heat, removing dampness, eliminating jaundice. HGD has been used in med...
Correction: Boomerang and bones: Refining the chronology of the Early Upper Paleolithic at Obłazowa Cave, Poland
In vivo evaluation of the antibacterial properties of a poly-ε-lysine and hyaluronic acid coated intramedullary implant in a New Zealand White rabbit model
Peri-prosthetic joint infection (PJI) is a severe complication that can arise following joint replacement surgery. PJI treatment is extremely complex due to the formation of bacterial biofilms and the...
Clinical outcomes with lower versus conventional dose polymyxin B regimens in dialysis dependent and non-dialysis patients with gram-negative sepsis: A real-world propensity-score matched cohort study
Background Polymyxin B remains a key treatment option for infections caused by multidrug-resistant gram-negative bacilli, particularly in critically ill patients. However, its opti...
War-related vicarious trauma among healthcare providers in the war-torn tigray, Northern Ethiopia
Background Tigray War, which started in November 2020, has doubled the burden on healthcare professionals, causing both direct violence and indirect effects as they care for trauma...