Community awareness, perceptions, and management practices related to pre-eclampsia: An exploratory qualitative study in Mbale City, Eastern Uganda

E Enid Kawala Kagoya A Allan G. Nsubuga I Irene Atuhairwe P Prossy Nakattudde C Catherine Asiimwe C Chrispus Gidudu E Elizabeth Ajalo P Paul Waako J Julius Wandabwa L Lawrence Arach G Grace Mbabazi Atwakire M Milton Musaba R Ronald Kibuuka F Faith Nyangoma S Sheilla Mbanago J Joshua Mugabi V Violet Chemutai J Jesca Atugonza B Byron Jonathan Ewaala B Betty Nakawuka F Francis Okello R Richard Mugahi J Jackline Akello A Andrew Twineamatsiko M Moses Adroma K Kenneth Mugabe

Abstract

Background Pre-eclampsia and other hypertensive disorders of pregnancy are the second leading cause of maternal mortality globally, with 95% of deaths occurring in low- and middle-income countries. In Uganda, these conditions account for approximately 16% of maternal deaths. Despite their burden, little is known about women’s knowledge, perceptions, and management practices regarding pre-eclampsia in such settings, yet early recognition and care-seeking are critical to improving outcomes. Objective To explore community awareness, perceptions, and management practices related to pre-eclampsia in Mbale City, Eastern Uganda. Methods An exploratory qualitative study was conducted through face-to-face interviews with 81 women aged 18-49 years during a community outreach event on pre-eclampsia. Data was collected over six days (21 st -26th May 2024) by 28 trained research midwives stationed at various community sites. Interviews were audio-recorded, transcribed, and thematically analyzed using ATLAS.ti software. Results Participants exhibited limited and mixed understanding of pre-eclampsia, often associating it with symptoms such as swollen feet, headaches, body weakness, and high blood pressure, but also with misconceptions such as witchcraft, marital stress, and multiple pregnancies. Many lacked a local term for the condition. Women reported varied care-seeking responses, with some turning to traditional birth attendants and herbal remedies, while others sought biomedical care. Fear of death was a motivator for some to seek timely medical attention. Conclusion There was a critical gap in accurate knowledge and awareness of pre-eclampsia among women in Mbale City. Misconceptions and reliance on traditional remedies contribute to delayed care-seeking. Targeted, culturally appropriate educational interventions are urgently needed to improve early recognition, promote biomedical care, and enhance maternal and newborn outcomes.

Article Details

Journal PLoS ONE
Volume / Issue Vol. 21, Issue 3
Published March 04, 2026
Pages e0314674
ISSN 1932-6203
Publisher Public Library of Science

Journal Info

PLoS ONE

Public Library of Science

ISSN: 1932-6203 Open Access Health Sciences

Authors (26)

E

Enid Kawala Kagoya

A

Allan G. Nsubuga

I

Irene Atuhairwe

P

Prossy Nakattudde

C

Catherine Asiimwe

C

Chrispus Gidudu

E

Elizabeth Ajalo

P

Paul Waako

J

Julius Wandabwa

L

Lawrence Arach

G

Grace Mbabazi Atwakire

M

Milton Musaba

R

Ronald Kibuuka

F

Faith Nyangoma

S

Sheilla Mbanago

J

Joshua Mugabi

V

Violet Chemutai

J

Jesca Atugonza

B

Byron Jonathan Ewaala

B

Betty Nakawuka

F

Francis Okello

R

Richard Mugahi

J

Jackline Akello

A

Andrew Twineamatsiko

M

Moses Adroma

K

Kenneth Mugabe