PLoS ONE
Articles in this Issue
Virologic suppression among HIV-positive pregnant and lactating women receiving antiretroviral therapy in Africa: A systematic review and meta-analysis
Background The elimination of mother-to-child transmission of human immunodeficiency virus (HIV) is a key global public health priority. In Africa, virologic failure among people l...
Use of administrative data for evaluating trends in medically-attended Lyme disease, Manitoba, Canada, 2010–2021
While Lyme disease (LD) is the most common tick-borne disease reported to public health surveillance in North America and is increasingly recognized as a public health threat in Canada, it’s incidence...
Genetic, clinical, and biochemical profiling of Gilbert syndrome in a Nepali cohort: High prevalence of the UGT1A1 c.-3279T>G polymorphism and correlation with hematological parameters
Introduction Gilbert Syndrome (GS) is a common hereditary disorder characterized by intermittent jaundice. The pathogenesis is unconjugated hyperbilirubinemia due to reduced hepati...
A food-grade cell dissociation agent via regulatory pre-check framework
Advancements in cell-based foods require materials that meet the highest food safety standards. Conventional cell dissociation agents, such as animal-derived trypsin, pose significant risks including...
Productivity and quality-related traits of wheat germplasm affected by heat stress
Heat stress (HS) significantly impedes wheat production, making the development of heat-tolerant cultivars increasingly essential in the context of climate change. This study evaluated 153 elite sprin...
Retraction: A transcriptional signature associated with non-Hodgkin lymphoma in the blood of patients with Q fever
Understanding landowner preferences for traditional and nature-based solutions incentive programs in North Carolina, USA
Financial incentive programs, commonly administered by public institutions, have long supported sustainable land management practices in the United States, including soil conservation, water quality i...
Effect of impregnation with polyethylene glycols (PEGs) of different end groups on gas separation performance of cross-linked polyethylene oxide (PEO) membranes
Polymer membranes offer an extremely attractive solution for achieving sustainable carbon dioxide capture and have the potential for large-scale application. The authors prepared almost amorphous poly...
Combining CRP testing and patient information leaflets to safely reduce antibiotic use for acute respiratory tract infections in adults: Protocol for the 2CARE randomised controlled trial in Kyrgyz primary care
Background Antimicrobial resistance (AMR) is a major health challenge in Kyrgyzstan, where acute respiratory tract infections (ARTIs) are common and frequently treated with antibio...
DNA source and primer choice affect the reliability of metabarcoding for nematode community profiling in agricultural soils
The advent of metabarcoding has greatly advanced our understanding of nematode ecology by overcoming many limitations associated with traditional morphology-based methods. The NF1–18Sr2b (NF1) is the...
A computer vision approach for the grading of cotton base load ages in measuring the performance of washing machine
The performance testing standards for washing machines specify clear requirements regarding the age of the base load used. To enable non-contact detection of the service life of the test fabric and th...
Spatial and temporal pattern evolution and driving characteristics of rural settlements in Xilingol League from 1915 to 1980
Population migration and agricultural expansion have profoundly reshaped the rural characteristics of Xilingol League, a typical pastoral region in northern China. From the perspective of historical g...
Why do self-referent cues facilitate mathematical word problem-solving? Insights from eye tracking
Associating information with the self enhances processing of that information, with simple text cues like self-referent pronouns (i.e., ‘You’) increasing response speed and accuracy in processing task...
Sex- and nationality-based participation and performance trends in the Swissman Xtreme Triathlon (2019–2025)
Background Participation and performance trends are well investigated for the IRONMAN ® triathlon. For Xtreme Tri...
Privacy-preserving multimodal federated learning pipeline for cyber-resilient healthcare systems
The integration of Internet of Things (IoT) devices and electronic medical records (EMRs) has transformed healthcare delivery but has also created new vulnerabilities to cyberattacks that threaten bot...
Evolutionary game analysis of emergency medical supply production capacity reserves in nonprofit organizations: A theoretical perspective
Since the 21st century, global public health emergencies have occurred frequently, posing severe threats to the economic development and social stability of countries worldwide. Against this backdrop,...
Predicted meta-omics: A potential solution to multi-omics data scarcity in microbiome studies
Imbalances in the gut microbiome have been linked to conditions such as inflammatory bowel disease, diabetes, and cancer. While metagenomics and amplicon sequencing are commonly used to study the micr...
Examining the mediating effects of metabolic syndrome components on the relationship between dairy product consumption and nonalcoholic fatty liver disease in Korean adults
Objective Dairy products are known to improve blood lipid profiles and insulin sensitivity and to reduce risk factors for metabolic syndrome (MetS) and nonalcoholic fatty liver dis...
Integrative bioinformatics and machine learning identify shared molecular mechanisms and diagnostic biomarkers between Helicobacter pylori infection and atrial fibrillation
Background Helicobacter pylori ( H. pylori ) infection and atrial fibrillation(AF) are majo...
Inconsistent condom use and its associated factors among female sex workers in African countries: Systematic review and meta-analysis
Background Inconsistent condom use represents the most proximal behavioral risk factor for acquisition and transmission of sexually transmitted infections, including human immunode...
Genetic diversity of Schima superba based on physiological traits and SSR markers
Schima superba is an ecologically and economically valuable evergreen tree that plays a key role in reforestation, firebreak establishment, and urban landscaping in subtropical Chi...
Assessment of peak bone mineral density and its associated factors in Vietnamese adults: A cross-sectional study
Introduction Osteoporosis is a growing public health concern in Vietnam, yet population-specific reference data for peak bone mineral density (PBD) remain limited. This study aimed...
An automatic weighing device for measuring the consumption of cleaning agents in mechanical cleaning equipment
Objective This study aims to develop an automatic weighing device based on embedded technology for accurately monitoring the consumption of various cleaning agents during each clea...
Research on hybrid cloud resource scheduling optimization algorithm based on EMPA-ASA
Hybrid–cloud scheduling must balance cost, performance, and reliability; yet existing approaches often suffer from burdensome parameter tuning, a limited set of optimized QoS indicators, and high comp...
Prevalence, associated factors, and association of intimate partner violence and suicidal behaviors among women of reproductive age in Asia: Protocol for a systematic review and meta-analysis of cross-sectional studies
Intimate partner violence (IPV) is strongly linked to suicidal behaviors (ideation, plans, attempts), affecting 1 in 3 women globally, with prevalence varying across regions. Sociocultural and economi...