Use of administrative data for evaluating trends in medically-attended Lyme disease, Manitoba, Canada, 2010–2021

M Maria Major S Susan Horton N Natalie Nightingale K Kate Halsby F Frederick J. Angulo J James Stark H Holly Yu M Mark Loeb I Irene Wang S Saranya Nair C Calum S. Neish D Doneal Thomas C Chloe McDonald S Samuel Torres-Florez A Ana G. Grajales S Sarah J. Willis

Abstract

While Lyme disease (LD) is the most common tick-borne disease reported to public health surveillance in North America and is increasingly recognized as a public health threat in Canada, it’s incidence may be underreported. Our study aims to estimate medically-attended LD incidence in Manitoba, Canada, using administrative health data. We identified medically-attended LD cases in Manitoba from 2010 − 2021 in a claims database (Manitoba Population Research Data Repository), which contains the health records of >95% of the residents of Manitoba, using diagnostic codes, antibiotic dispensations, and laboratory results. The incidence of claims-based LD cases ranged from 8.4 to 28.5 per 100,000 population per year, 5.1 to 11.0 times higher than the incidence of surveillance-reported LD cases. The incidence of claims-based LD cases was particularly higher than the incidence of surveillance-reported LD cases in females and health regions with a low surveillance-reported incidence. Our study suggests that medically attended LD is more common than reported in surveillance. Further study is required to identify barriers to reporting. Interventions are needed to reduce the substantial burden of LD in Manitoba.

Article Details

Journal PLoS ONE
Volume / Issue Vol. 21, Issue 4
Published April 13, 2026
Pages e0342260
ISSN 1932-6203
Publisher Public Library of Science

Journal Info

PLoS ONE

Public Library of Science

ISSN: 1932-6203 Open Access Health Sciences

Authors (16)

M

Maria Major

S

Susan Horton

N

Natalie Nightingale

K

Kate Halsby

F

Frederick J. Angulo

J

James Stark

H

Holly Yu

M

Mark Loeb

I

Irene Wang

S

Saranya Nair

C

Calum S. Neish

D

Doneal Thomas

C

Chloe McDonald

S

Samuel Torres-Florez

A

Ana G. Grajales

S

Sarah J. Willis