PLoS ONE
Articles in this Issue
Correction: Redefining ‘normal’: A Canadian case study of cancer survivors’ experiences remaining and/or returning to work during the COVID-19 pandemic
Can participative leadership and LMX congruence promote collective organizational engagement?
Employee engagement has been widely recognized as an important indicator of organizational functioning and performance. While prior research has primarily examined engagement at the individual level,...
Sequencing complete plasmids on Oxford Nanopore Technologies sequencers using R2C2 and Chopper
Plasmids are ubiquitous tools in molecular biology which are used for a large variety of experiments within academic and commercial labs. Both new and old plasmids have to undergo sequencing-based ana...
Characterization of a C9orf72 Knockout Danio rerio model for ALS and cross-species validation of potential therapeutics screened in Caenorhabditis elegans
Intronic hexanucleotide repeat expansions in the C9orf72 gene represent the most common genetic cause of the neurodegenerative diseases amyotrophic lateral scle...
Effects of scapular-focused movement-based exercises on sports performance of athletes with scapular dyskinesis: A systematic review
Background Scapular dyskinesis is a common dysfunction among athletes, particularly in overhead sports, leading to pain, reduced range of motion (ROM), and impaired performance. Mo...
Development and external validity of a nurse-led intervention program to improve palliative care and quality of dying and death in intensive care unit
Introduction In Japan, end-of-life care in intensive care units (ICU) remains inconsistent and often suboptimal, contributing to variability in the quality of dying and death. This...
Effects of complex training on jump performance and neuromuscular activation in volleyball athletes: A controlled study
This study examined the integrated effects of complex training combining barbell back squats (BBS) and drop jumps (DJ) on jump performance and concentric-phase neuromuscular activation in volleyball a...
Motor planning, initiation and execution of shoulder abduction against gravity: Evidence from startReact
Stroke affects the sensorimotor control of the upper extremity, limiting functional movements which require coordination between the shoulder and distal joints. StartReact has been used to investigate...
Molecular identification and microbiome profiling of household casebearer, Phereoeca sp. (Lepidoptera: Tineidae) from Malaysia: Potential implications for human skin irritation
In Malaysia, anecdotal accounts have linked the household casebearer (Lepidoptera: Tineidae) to skin lesions and localized inflammation; however, scientific evidence is lacking, and the species’ taxon...
IGF1/IGF-1R promotes hepatocellular carcinoma progression by activating the Akt/GSK-3β pathway
The incidence of hepatocellular carcinoma (HCC) is increasing each year, with challenges such as increasing drug resistance and a high post-treatment recurrence rate. Therefore, investigating the nove...
Editorial Note: DNA persistence and relapses questions on the treatment strategies of Enterococcus infections of prosthetic valves
Inhibition of Chikungunya virus nsP2 protease in vitro by scorpion venom peptide pantinin-1
Climate change has facilitated the spread of arboviruses like the Chikungunya virus (CHIKV). CHIKV, a re-emerging virus from the Togaviridae family, has caused...
Estimating GPS-based social aggregation metrics using collar data
Understanding social aggregation patterns in ungulate herds is essential for gaining behavioral insights, optimizing resource use, reducing human-wildlife conflict, and managing disease risk. As chron...
Process performance and microbial community dynamics in semi-dry mesophilic co-digestion of crop residues and livestock manure
Semi-dry anaerobic co-digestion represents a promising strategy for efficient resource utilization of diverse agricultural wastes; however, its operational performance under mesophilic conditions and...
Scientific work and knowledge of scientific methods in local public health authorities (SCOPE) – wish or reality? Results of a semi-standardized cross-sectional survey of local public health authorities in Germany (Part 1)
In Germany, there are efforts to strengthen scientific work in local public health authorities (LHA) to improve efficiency and effectiveness and to ensure quality in the public health service (PHS). T...
An interpretable deep learning framework for predictive modeling of postoperative infections in ICU patients
A significant proportion of intensive care unit (ICU) patients undergo surgical procedures, and some may develop postoperative infections. Accurately predicting postoperative infection risk and identi...
First record of Sigmodon minor (Rodentia) in the early Blancan of central Mexico: Asymmetrical dispersal from the Great Plains and paleoecology inferences
In this study, we report the first occurrence of Sigmodon minor (Cricetidae, Rodentia) in Mexico, from the early Blancan of the Pliocene in the San Miguel de Al...
Reference gene selection for RT-qPCR normalization in the drone testis of honey bee (Apis cerana) during meiosis stages
Drones are the males in the honey bee population that provide high quantity and quality sperm to mate with the queen and ensure colony reproduction. To understand spermatogenesis in the drone testis a...
Hypoxia regulates epithelial to mesenchymal transition-associated genes in human trophoblast cells by modulating DNA methylation
Successful pregnancy is dependent on an aptly developed and functional placenta. During placentation, epithelial cytotrophoblast cells (CTBs) transdifferentiate into migratory extravillous trophoblast...
Prognostic risk model based on cholesterol metabolism–Associated gene module for idiopathic pulmonary fibrosis
Background Idiopathic Pulmonary Fibrosis (IPF) is a progressive and fatal lung fibrosis disease with a complex molecular mechanism that remains incompletely understood. Previous st...
Stress relaxation constitutive model of rock based on Hausdorff derivative
Stress relaxation is a key time-dependent response that governs the long-term stability of deep underground rock engineering. In this study, staged uniaxial and triaxial stress relaxation tests on san...
The impact on healthcare facilities of the 2024 IV fluids shortage after Hurricane Helene: A mixed methods study
Background In September 2024, Hurricane Helene damaged the Baxter International Factory in North Carolina as well as the surrounding infrastructure, causing the factory to shut dow...
ATEdrug: A reliable human-in-the-loop annotation scheme for aspect term extraction and polarity detection in drug reviews
Pharmacovigilance is vital for post-market drug safety monitoring. Traditional trials inadequately capture adverse reactions. Patient-generated opinions offer valuable insights but pose challenges due...
Comparison of the effects of different types of treatment protocols on the median and overall survival rates of non-small cell lung cancer patients: A real-world retrospective study
Lung cancer treatment presents a major challenge globally. The advent of monoclonal antibodies (mAbs) has ushered in a new era in the treatment of non-small cell lung cancer (NSCLC). This study aimed...
Adaptive Feature Fusion Gate and Gated Channel-Spatial Attention in CNN-Transformer Models for Music Genre Classification
With the rapid growth of music data, automatic music genre classification has become a critical task in music information retrieval. Traditional methods based on handcrafted features are increasingly...